Benyi Li, Ph.D.

Associate Professor
Director of Basic Science Research
Department of Urology

M.D., Tongji Medical University, China, 1992
Ph.D., Fukui Medical University of Japan, 1997
Postdoctoral, Moffitt Cancer Center, 1998-2000
Postdoctoral, Baylor College of Medicine, 2000-2001


bli@kumc.edu

Critical to the prevention and treatment of urologic cancers is basic science research. In the Urologic laboratory at Kansas University Medical Center we are investigating the various causes of cancer. Dr. Benyi Li, M.D., PhD. received training in molecular biology and prostate cancer research in China, Japan, and Baylor College of Medicine,  Houston, TX. His interests focus on molecular pathways which cause prostate cancer to grow and metastasize. In addition, he has created an inducible Akt system to allow further study of the molecular mechanisms behind prostate cancer.

Selected Publications

Liu J, Youn H, Yang J, Du N, Liu J, Liu H, Li B. G-protein alpha-s and -12 subunits are involved in androgen-stimulated PI3K activation and androgen receptor transactivation in prostate cancer cells. Prostate. 2011 Feb 9.

Zhu Q, Yang J, Han S, Liu J, Holzbeierlein J, Thrasher JB, Li B. Suppression of glycogen synthase kinase 3 activity reduces tumor growth of prostate cancer in vivo. Prostate. 2010 Oct 28.

Li C, Ford ES, Li B, Giles WH, Liu S. Association of testosterone and sex hormone-binding globulin with metabolic syndrome and insulin resistance in men. Diabetes Care. 2010 Jul;33(7):1618-24.

Gao X, Pang J, Li LY, Liu WP, Di JM, Sun QP, Fang YQ, Liu XP, Pu XY, He D, Li MT, Su ZL, Li B. Expression profiling identifies new function of collapsing response mediator protein 4 as a metastasis-suppressor in prostate cancer. Oncogene. 2010 Aug 12;29(32):4555-66.

Yang J, Takahashi Y, Cheng E, Liu J, Terranova PF, Zhao B, Thrasher JB, Wang HG, Li B. GSK-3beta promotes cell survival by modulating Bif-1-dependent autophagy and cell death. J Cell Sci. 2010 Mar 15;123(Pt 6):861-70.

Sun A, Tang J, Terranova PF, Zhang X, Thrasher JB, Li B. Adeno-associated virus-delivered short hairpin-structured RNA for androgen receptor gene silencing induces tumor eradication of prostate cancer xenografts in nude mice: a preclinical study. Int J Cancer. 2010 Feb 1;126(3):764-74.

Saleem M, Murtaza I, Tarapore RS, Suh Y, Adhami VM, Johnson JJ, Siddiqui IA, Khan N, Asim M, Hafeez BB, Shekhani MT, Li B, Mukhtar H. Lupeol inhibitsproliferation of human prostate cancer cells by targeting beta-catenin signaling. Carcinogenesis. 2009 May;30(5):808-17.

Li H, Ruan G, Li Z, Liu Z, Zheng X, Zheng H, Cheng G, Li B, Zhan M. The calcimimetic R-568 induces apoptotic cell death in prostate cancer cells. J Exp Clin Cancer Res. 2009 Jul 14; 28:100.

Pi M, Chen L, Huang MZ, Zhu W, Ringhofer B, Luo J, Christenson L, Li B, Zhang J, Jackson PD, Faber P, Brunden KR, Harrington JJ, Quarles LD. GPRC6A null miceexhibit osteopenia, feminization and metabolic syndrome. PLoS One. 2008;3(12):e3858.

Last modified: Oct 11, 2011

Benyi Li, M.D., PhD.

Contact

Benyi Li, Ph.D.
Associate Professor
Director of Basic Science Research

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