Yu Lab Publications

  1. Yu ASL, Enck AH, Lencer WI, Schneeberger EE: Functional expression of claudin-8 reveals a role in the paracellular cation barrier. J Biol Chem 278:17350-17359, 2003.
  2. Li WY, Huey CL, Yu ASL: Expression of claudins 7 and 8 along the mouse nephron. Am J Physiol Renal Physiol 286:F1063-F1071, 2004.
  3. Huey CL, Riepe FG, Sippell WG, Yu ASL: Genetic heterogeneity in autosomal dominant pseudohypoaldosteronism type I: Exclusion of claudin-8 as a candidate gene. Am J Nephrol 24:483-487, 2004.
  4. Yu ASL, McCarthy KM, Francis SA, McCormack JM, Lynch RD, Schneeberger EE: Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells. Am J Physiol Cell Physiol 288:C1231-C1241, 2005.
  5. Angelow S, Kim KJ, Yu ASL: Claudin-8 modulates paracellular permeability to acidic and basic ions in MDCK II cells. J Physiol 571:15-26, 2006.
  6. Van Itallie CM, Rogan S, Yu ASL, Seminario L, Holmes J, Anderson JM: Two splice variants of claudin-10 in the kidney create paracellular pores with different ion selectivities. Am J Physiol Renal Physiol 291:F1288-1299, 2006.
  7. Angelow S, Schneeberger EE, Yu ASL: Claudin-8 expression in renal epithelial cells augments the paracellular barrier by replacing endogenous claudin-2. J Memb Biol 215(2-3):147-59, 2007.
  8. Angelow S, El-Husseini R, Kanzawa SA, Yu ASL: Renal localization and function of the tight junction protein, claudin-19. Am J Physiol Renal Physiol 293(1):F166-77, 2007.
  9. Selvam S, Thomas PB, Gukasyan HJ, Yu AS, Stevenson D, Trousdale MD, Mircheff AK, Schechter JE, Smith RE, Yiu SC. Transepithelial bioelectrical properties of rabbit acinar cell monolayers on polyester membrane scaffolds. Am J Physiol Cell Physiol 293:C1412-9, 2007.
  10. Scheiermann C, Meda P, Aurrand-Lions M, Madani R, Yiangou Y, Coffey P, Salt TE, Ducrest-Gay D, Caille D, Howell O, Reynolds R, Lobrinus A, Adams RH, Yu ASL, Anand P, Imhof BA, Nourshargh S. Expression and function of junctional adhesion molecule (JAM)-C in myelinated peripheral nerves. Science 318:1472-5, 2007.
  11. Sabath E, Negoro H, Beaudry S, Paniagua M, Angelow S, Shah J, Grammatikakis N, Yu ASL, Denker BM. Ga12 regulates both maintenance and assembly of tight junctions through Src and the Hsp90 heat shock protein complex. J Cell Sci 121:814-24, 2008.
  12. Yu ASL, Kanzawa SA, Usorov A, Lantinga-van Leeuwen IS, Peters DJM. Tight junction composition is altered in the epithelium of polycystic kidneys. J Pathol 216(1):120-128, 2008.
  13. Yu ASL, Cheng, MH, Angelow S, Günzel D, Kanzawa SA, Schneeberger EE, Fromm M, Coalson RD. Molecular basis for cation selectivity in claudin-2-based paracellular pores: Identification of an electrostatic interaction site. J Gen Physiol, 133: 111-127, 2009.
  14. Ahlstrom R, Yu ASL. Characterization of the kinase activity of a WNK4 protein complex. Am J Physiol Renal Physiol, 297(3):F685-92, 2009.
  15. Angelow S, Yu ASL. Structure-function studies of claudin extracellular domains by cysteine-scanning mutagenesis. J Biol Chem, 284(42):29205-17, 2009.

Recent Reviews

  1. Yu ASL: Elucidating the structural basis of membrane transport protein function: Light at the end of the channel? Curr Opin Nephrol Hypertens 11:523-526, 2002.
  2. Yu ASL: WNK signalling in the distal tubule: An inhibitory cascade regulating salt transport. Am J Physiol Renal Physiol 290:F617-618, 2006.
  3. Angelow S, Yu ASL: Claudins and paracellular transport; an update. Curr Opin Nephrol Hypertens, 16(5):459-464, 2007. PMID: 17693762
  4. Angelow S, Ahlstrom R, Yu ASL: Biology of claudins. Am J Physiol Renal Physiol 295(4):F867-76, 2008. PMID: 18480174
  5. Yu ASL: Molecular basis for cation selectivity in claudin-2-based pores. Ann NY Acad Sci 1165: 53-57, 2009.
  6. Angelow S, Yu ASL: Cysteine mutagenesis to study the structure of claudin-2 paracellular pores. Ann NY Acad Sci 1165: 143-147, 2009.
  7. Günzel D, Yu ASL. Function and regulation of claudins in the thick ascending limb of Henle. Pflüger's Arch Eur J Physiol 458, 77-88, 2009.
  8. Yu ASL: Structure-function studies of the claudin pore. In: Current Topics in Membranes, volume 65: Claudins; Yu ASL [editor]. Elsevier, Philadelphia, PA.
  9. Yu ASL: Electrophysiological characterization of claudin ion permeability using stably transfected epithelial cell lines. In: Claudins: Methods and Protocols; Turksen K [editor] from the Methods in Mol. Biol. book series. Humana Press, New York, NY.

Yu Lab

Last modified: May 01, 2013