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Airway and Asthma Translational Research Unit (AATRU)

AATRU Lab Staff

Our research focuses on understanding the origins of asthma and how we can decrease asthma morbidity and mortality using translational methods.

Dr. Mario Castro, MD, MPH, Division Chief of Pulmonary Critical Care and Sleep Medicine; Vice Chair for Clinical and Translational Research, Director of the Rainbow Clinical and Translational Science Unit (CTSU, Frontiers), leads the AATRU group which currently has >25 ongoing studies, all of which have opportunities for students, residents, fellows, and junior faculty to perform focused research in an area of interest. 

Interested in Enrolling in a Clinical Study?

Please click here and complete the clinical study interest form.

Precision Interventions for Severe and/or Exacerbation Prone Asthma (Network (PrecISE, NIH funded):
is a precision-medicine, biomarker-driven, highly novel adaptive controlled trial to establish a new treatment paradigm for severe asthma.

Severe Asthma Research Program (SARPIII, NIH funded):
is a multi-center longitudinal study to improve the understanding of severe asthma and to develop better treatments. In SARP we seek to gain a better understanding of asthma and its endotypes, in children and adults, by defining the disease at the molecular and cellular levels in the context of the temporal phenotypic expression of the disease.

Asthma Clinical Research Center (ACRC, ALA funded):
we are performing clinical research in adult and pediatric asthma through a national network of 40 centers.

HERO-HCQ (PCORI funded):
is a randomized clinical trial of approximately 15,000 HERO Registry participants. It will test whether hydroxychloroquine (HCQ, brand name Plaquenil®) can prevent COVID-19 infection in healthcare workers.

CoVPN (NIH funded):
COVID-19 Prevention Network for a Phase III Randomized, Double-blind, Controlled Multicenter Study in Adults to Determine the Safety, Efficacy, and Immunogenicity of AZD1222, for the Prevention of COVID 19. 

Clinical Trials:
View the complete list and description of current and future AATRU Studies in Asthma and opportunities to enroll in here.
Interested Participants: Please fill out the quick form and one of our fantastic staff will contact you ASAP.

AATRU Laboratory:
Complete list and description of current translational research projects, the AATRU Biobank and opportunities to perform research to understand the pathophysiology of asthma endotypes is available here.

AATRU Imaging:
Complete list and description of novel Imaging Techniques being developed for asthma and airway diseases is coming soon. 

Interested in Enrolling in a Clinical Study?

Please click here and complete the clinical study interest form.

Last modified: Aug 12, 2020