Navneet Kaur Dhillon, PhD
Pulmonary and Critical Care Medicine
Ph.D., Post Graduate Institute of Medical Education & Research, Chandigarh, India, 2003
Post-doctorate Fellowship, The University of Kansas Medical Center, Kansas City, KS, 2003-2007
Publications: Click here
Research in Dr. Dhillon's laboratory is focused on understanding the pathogenesis of HIV-associated end stage diseases particularly cardio-pulmonary disorders. The complications associated with AIDS in the ART era are evolving away from those of an infectious nature and towards noninfectious consequences of prolonged survival. HIV-related pulmonary hypertension (HIV-PAH) is a particularly severe example and the majority of HIV-PAH occurs in individuals with a history of intravenous drug use. Primary research efforts are aimed at understanding mechanistically how HIV-1 and drugs of abuse contribute alone and in concert to the vascular dysfunction associated with PAH. Other focus of the lab is to unravel the interplay of macrophages, cytokines and chemokines in lung infections associated with HIV-infection and cigarette smoking.
Current Research is aimed at:
• Elucidating the role of non-coding RNAs in the regulation of proliferative and anti-proliferative cascades in pulmonary smooth muscle cells.
• Defining the role of autophagy/mitophagy in the shift of early apoptotic phase of pulmonary endothelium to the later proliferative phase associated with angio-obliteration.• Investigating the role of inflammatory cell-derived extracellular vesicles in pulmonary vascular remodeling.
Parker B Francis Summer Fellowship Program
Dr. Dhillon is a Director of the PBF Summer Fellowship Program that provides opportunities to undergraduate students, particularly those from underrepresented minorities in science and medicine for hands-on innovative research experience. For more information click here.