Michael Brimacombe, Ph.D.

Associate Professor, Department of Biostatistics

B.A., Applied Mathematics, Concordia University, Toronto, Canada
M.Sc., Statistics, University of Toronto, Toronto, Canada
M.A., Economics, University of Toronto, Toronto, Canada
Ph.D., Statistics, University of Toronto, Toronto, Canada

University of Kansas Department of Biostatistics Outstanding Graduate Teaching Award 2010-2011

Research Focus

Large Databases and High Dimensional Applications, Nonlinear Models, Disease Epidemiology and Genetics, Teaching of Biostatistics/Foundations of Statistics, Clinical Applications of Biostatistics.

Personal Mission Statement

Biostatistics is a blend of statistical concepts, mathematical modeling and applied science that supports most serious investigations of biomedical and other research endeavors in a Medical Center setting. The modeling of random variation across sets of individuals allows us for example to determine if a treatment works, if an epidemiologic exposure has a negative effect or if a cluster of genes is associated with a disease. KUMC is a growing academic and research center providing a wide variety of research opportunities to participate individually or with colleagues in Medicine, Nursing, Allied Health, Basic Sciences, Clinical Sciences and other disciplines. The Department of Biostatistics offers M.S. and Ph.D. biostatistics training in a Medical Center environment, making for a varied and interesting place to work and learn.


Top 15 Publications


1. "Prenatal & Birth Complications in Autism," (2007). M. Brimacombe, X. Ming, M. Lamendola. Matern Child Health J DOI 10.1007/s10995-006-0142-7. PMID: 17053965.

2. "Autism Post-Mortem Neuroinformatic Resource: The Autism Tissue Program (ATP) Informatics Portal," (2007). M. Brimacombe, J. Pickett, R. Pickett.  J Autism Dev Disord. 2007 Mar;37(3):574-9. PMID: 16933088 .

3. "A Comparison of Fetal Demise Case Series Drawn from Socio-economically Distinct Counties in New Jersey" (2007). M. Brimacombe, D. Heller, S. Zamudio. Fetal Pediatr Pathol. 2007 Sep-Dec;26(5-6):213-22. doi: 10.1080/15513810701818353. PMID: 18363153.

4. "Pediatricians Knowledge, Training, and Experience in the Care of Children With Fetal Alcohol Syndrome," (2006) S. Gahagan, TT Sharpe, M. Brimacombe, Y. Fry-Johnson, R. Levine, M. Mengel, M. O'Connor, B. Paley, S. Adubato G. Brenneman. Pediatrics. 2006 Sep;118(3):e657-68. PMID: 16950957.

5. "Comprehensive Approaches to the Screening, Diagnosis & Prevention of Fetal Alcohol Syndrome in New Jersey," (2005). M. Brimacombe, S. Adubato, D. Cohen, A. Wilson. JFAS Intl. 2005;3:e4 - Jan. 2005. 

6. "Shoulder Dystocia Related Fetal Neurological Injuries: The Predisposing Role of Forceps and Ventouse Extractions." M Brimacombe, L Iffy, J Appuzzio Varadi V, Nagy B, Raju V, Portuondo N. Arch Gynecol Obstet. 2008 May;277(5):415-22. Epub 2007 Sep 29. PMID: 17906870.    

7. "Chronic Obstructive Pulmonary Disease and Mortality Following Hip Fracture: A Population-based Cohort Study," (2008).  C. de Luise, M Brimacombe, L Pedersen, HT Sørensen. European J of Epidemiol. 2008;23(2):115-22. Epub 2007 Nov 24. PMID: 18038248.

8. "Comorbidity and Mortality Following Hip Fracture: Population-based Cohort Study," (2008). C. de Luise, M. Brimacombe, H. Sorenson. Aging Clin Exp Res. 2008 Oct;20(5):412-8. PMID: 19039282. 

9. "Antibiotic Resistance and Single Nucleotide Polymorphism Cluster Grouping Type in a Multi-national Sample of Mycobacterium Tuberculosis Isolates," (2007). M. Brimacombe, M. Hazbon, As Motiwala, D. Alland. Antimicrob Agents Chemother. 2007 Nov;51(11):4157-9. Epub 2007 Sep 10. PMID: 17846140.

10. "Population Genetics Study of Isoniazid Resistance Mutations and Evolution of Multi-Drug Resistant Mycobacterium tuberculosis," (2006). MH Hazbón, M. Brimacombe, M Bobadilla del Valle, M Cavatore, MI Guerrero, M Varma-Basil, H Billman-Jacobe, C Lavender, J Fyfe, L García-García, CI León, M Bose, F Chaves, M Murray, KD.Eisenach, JSifuentes-Osornio, MD Cave, A Ponce de León, D Alland. Antimicrob Agents Chemother. 2006 Aug; 50(8): 2640-9. PMID: 16870753.

11. "Species Diversity: Macroecological Assessments by Diet and Biome and Evidence of Nonlinearity and Mixed Distributions," (2001). M. Silva, M. Brimacombe, J. Downing. Global Ecology & Biogeography, 10, pp. 469-486.

12. "Conditional Bayesian Significance Levels and Central Bayes Regions: Econometric Applications," M. Brimacombe, in Advances in Econometrics: Bayesian Computational Methods and Applications," Volume 11A, Part A, pp. 255‑272. T. Fomby, E.Carter Hill eds. (1995).

13. "Effects of Phenobarbital Treatment on Serum Thyroxine and Thyroid-Stimulating Hormone Concentrations in Epileptic Dogs," (1999). CL. Gaskill, SA. Burton, HCJ. Gelens, SL. Ihle, JB. Miller, DH. Shaw, M. Brimacombe, AE. Cribb. J Am Vet Med Assoc. 1999 Aug 15;215(4):489-96. PMID: 10461631.

14. "What Determines Health? To Where Should We Shift Resources? Attitudes Towards The Determinants of Health Among Multiple Stakeholder Groups in Prince Edward Island, Canada," (2001).  J. Eyles, M. Brimacombe, P. Chaulk, G. Stoddart. T. Pranger, O. Moase. Soc Sci Med. 2001 Dec;53(12):1611-19. PMID:11762887. 

15. "Gender Disparities in the Diagnosis and Treatment of Hypertrophic Cardiomyopathy," (2008). M. Brimacombe, D. Walter, L. Salberg. J Womens Health (Larchmt) 2008 Dec;17(10):1629-34. doi: 10.1089/jwh.2007.0734.. PMID: 19049357.

Last modified: May 03, 2013

Michael Brimacombe


Michael Brimacombe, Ph.D.
Associate Professor, Department of Biostatistics

P: (913) 588-4785