Brooke L. Fridley, Ph.D.

Associate Professor, Department of Biostatistics
Director, Biostatistics and Informatics Shared Resource, The University of Kansas Cancer Center
Site Director, K-INBRE Bioinformatics Core

B.S., Mathematics, Truman State University, Kirksville, MO
M.S., Statistics, Iowa State University, Ames, IA
Ph.D., Statistics, Iowa State University, Ames, IA


Research Focus

Statistical Genetics / Genomics, Molecular Epidemiology, Bioinformatics, Cancer Genomics and Ovarian Cancer, Bayesian Methods.

Personal Mission Statement

Discovering the role of genomics in human diseases will pave the way toward improvements in disease diagnosis, treatment and prevention. My research is focused on the development of sophisticated statistical and bioinformatics tools for the analysis of high-dimensional "omic" data. These tools will aid researchers in the analysis and interpretation of genomic, epigenomic and transcriptomic data to determine functionally relevant loci associated with complex traits and diseases. My research is focused primarily on development methods for data integration, including Bayesian methods, molecular clustering and gene set analysis approaches. Recently, I also started investigating and developing analysis methods for next-generation sequence data that will aid researchers in the interpretation of this high-dimensional data, including rare variants. In addition to my statistical research, I am actively involved in numerous genomic projects, primary in the area of cancer and cancer pharmacogenomics. Many of these studies deal with both candidate genes and genome-wide approaches, along with multiple types of genomic data, such as genotypic, methylation and mRNA expression.

 

Click here to view Dr. Fridley's Analysis Code & Software for Genomic Studies

 

Web of Science Profile and Publications: http://www.researcherid.com/rid/D-8315-2015

 

Last modified: May 08, 2015

Contact

Brooke L. Fridley, Ph.D.
Associate Professor, Department of Biostatistics
Director, Biostatistics and Informatics Shared Resource, The University of Kansas Cancer Center
Site Director, K-INBRE Bioinformatics Core

P: (913) 945-5039
F: (913) 588-0252
bfridley@kumc.edu

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