The Cardiovascular Research Institute (CVRI) was founded with the broad goal of promoting cardiovascular research across basic, clinical and translational domains. Consistent with this goal, the CVRI provides an integrative framework for cardiovascular research conducted at the University of Kansas Medical Center and the University of Kansas Hospital.
The CVRI connects investigators from a wide spectrum of cardiovascular research that includes cellular and molecular investigation, physiological experimentation in whole animals, investigator-initiated clinical research, population studies, large multicenter clinical trials, and translational research that brings discoveries from the bench to the bedside. Housed in two physically proximal locations, the basic and clinical/translational divisions of the CVRI provide ample opportunities for physicians and scientists to work together on clinically and scientifically important questions. The ongoing projects are predictably diverse and include studies addressing fundamental questions in adult stem cell biology, cell therapy for heart repair, studies of cytokines and transcription factors as they impact cardiac injury and repair, induced pluripotent stem cells, and others. The clinical trials include implantation of percutaneous aortic valve in frail patients, and examining the impact of yoga on atrial fibrillation outcomes, among others.
Aside from pursuing excellence in science and innovation, training the future generation of scientists and physicians remains one of our primary goals. The multidisciplinary research operations within the CVRI provide great opportunities for trainees to learn about a broad spectrum of techniques and approaches relevant to cardiovascular research. The close collaborations between the basic and clinical divisions provide translational insights to future physician-scientists.
Despite the progress that has been made, the importance of cardiovascular research in today's world cannot be overemphasized. Through research and innovation, we at the CVRI strive to create the knowledge that will bring new therapies to patients. And as the CVRI grows, we expect to make greater contributions in our collective fight against cardiovascular diseases, which remains the nation's number one health problem.
Buddhadeb Dawn, MD, FACC, FAHA, FACP
Professor of Medicine and Molecular and Integrative Physiology
Maureen and Marvin Dunn Professor of Cardiovascular Diseases
Director, Division of Cardiovascular Diseases
Director, Cardiovascular Research Institute
Director, Midwest Stem Cell Therapy Center