Marriyam Moten, MD, MPH,MHA, FACC

Director, Non- invasive Cardiology, Kansas City VA Medical Center
Medical School, Dow Medical College, Karachi University, Karachi, Pakistan
Residency, Resident Internal Medicine, Cook County Hospital, Chicago, Illinois
Fellowship, Jewish Hospital of St. Louis at Washington University, St. Louis, MO
Fellowship, Clinical Cardiology Research Fellow, Non-Invasive Cardiology, Department of Echocardiography, TUFTS University School of Medicine, New England Medical Center, Boston, MA
Fellowship, Cardiology Fellow, TUFTS University School of Medicine, New England Medical Center, Boston MA

Clinical Interests

Dr. Moten specializes in cardiovascular diseases and cardiac non-invasive imaging that includes echocardiography and nuclear cardiology. She is focused on cardiac risk factor modifications that include hypercholesterolemia and hypertension. She has an interest in heart disease and atherosclerosis in women and veterans.

Research Interests

Dr. Moten's research interests are focused on the secondary and tertiary prevention of the effects of diabetes, prevention and treatment of cardiac arrhythmias, anticoagulation in cardiac diseases and cardiac risk factor modifications.

Publications

Moten, M., Pandian NG. Echocardiography in Cardiac Tamponade (review and report) Cardiovascular review and report 1988; 9(9): 46

Pandian NG, Moten M. Echo Quiz: Dyspnea, Fatigue, and Heart Murmur. Atrial Septal Defect Choices in Cardiology 1988: 22 (5): 220

Bojar R, Diehl J, Moten M, Payne D, Rastegar H, Stetz J, Pandian NG, Cleveland R. Clinical and Hemodynamic Performance of  Ionescu -Shiley Valves in Small Aortic Root. Results in 117 patients with 17 and 19 mm. Valves. Journal of Thoracic and Cardiovascular Surgery  1989; 87(6):1087-95

Moten.M. Critique: The Antihypertensive Effect of Fish Oil, Cardiac Chronicle 1990:4 (3): 9

Moten M., Lessmier T Critique: Characteristic Doppler Echocardiographic Pattern of Mitral Velocity in Severe Aortic Regurgitation, Cardiac Chronicle 1990: 4(9) 13

Moten. M. Critique: Should Thrombolytics Be Administered in Mobile Intensive Care Unit Patients with Myocardial Infarction? A pilot study. Cardiac Chronicle 1990:4 (12); 10-11

Freedman RR, Subhash CS, Moten M, Migaly P Local Temperature Modulates A-1 and A-2 Adrenergic Vasoconstriction in Men. AM J Physiology 263 Hear Circulation Physiology, 1992; 32: H 197-H 200

Freedman RR Moten M, Migaly P Mayer M.  Cold-Induced Potentiation of Alpha-2 Adrenergic Vasoconstriction in Primary Raynauds Diseases Arthritis and Rheumatism 1993: 35(5): 685-90

Freedman RR, Moten M. Venodilation in Raynaud's Disease (Letter) Lancet 1994; 343; 678

Kosmas CE, Mallozzi M, Moten M, Banka VS. Clinical symptomatology of coronary artery disease and results of exercise thallium scintigraphy: gender-related differences. Indian Heart J. 1997 Sep-Oct;49(5):497-501

Angiotensin-Converting-Enzyme Inhibition in Stable Coronary Artery Disease. The PEACE Trial Investigators. NEJM 2004 Nov 11; 2058-2068

Ayhan A. Zia, MD; Babatunde O. Komolafe, MD; Marriyam Moten, MD; Robert A. Ahokas, PhD; Jesse E. McGee, MD; E. William Rosenberg, MD; Syamal K. Bhattacharya, PhD; Karl T. Weber, MD Supplemental Vitamin D and Calcium in the Management of African-Americans with Heart Failure Having Hypovitaminosis D  The American Journal of the Medical Sciences 2011 Feb 341(2) :113-118

Isolated left atrial hemangioma presenting as angina.  J Mcgee M Moten et al., submitted September  2010 to Journal of echocardiography

Research Projects

1989-1993; A Multi-Center Comparison of the Effects of Isradipine and Diuretic            Treatment Regimen of Atherosclerosis in Patients With Essential Hypertension (MIDAS) Sandoz Pharmaceutical Study Conducted at VAMC, Allen Park,

1992-1993; A Multicenter Study of the Effects of Doxazosin on Blood Pressure, Diabetic Control, Side Effect Profile, and Renal Function in Hypertensive Patients with Non-Insulin Dependent Diabetes Mellitus Conducted at VAMC, Allen Park, MI

1990-1993 Behavioral Treatment of Raynaud's phenomenon, Department of Health and Human Services.   Principal Investigator, Dr. R Freedman.  $893,519.00 study conducted at Department of Psychiatry and Behavioral Medicine, Lafayette Clinic, Detroit, MI (Grant Support)

1991-1994 Multicenter Trial to Evaluate the Effect of Digitalis on Mortality in Heart Failure (DIG) VA NHLBI Study

1993-1998 Sex Hormone Modulates Vascular Adrenoreceptors in Women.  Principal Investigator, Dr. R Freedman.   NHLBI submitted 12/9/92

1992-1993 A Phase IV Study to Evaluate the Effect of Intervention with Intravenous Milrinone and Dobutamine on the Course of Acute Hospital Admission for Congestive Heart Failure.  Sanofi Winthrop Clinical Multiphase Research Inc.  Project #140.01 Study Conducted at VAMC, Allen Park, MI

1994-95 Principal Investigator Episcopal Hospital for CORE (Collaborative Organization for Rheothrx Injection Evaluation) International Phase II Clinical Trial.

2000-04 Co-Investigator at VA Pittsburgh Healthcare System, PA.  Prevention of Events with Angiotensin Converting Enzyme Inhibition (PEACE).

2001 - March 2004; Co-Investigator at VA Pittsburgh Healthcare System, PA.  Double Blind, Randomized, Placebo-Controlled Trial Evaluating the 2001 Onwards-Safety and Efficacy of Eplerenone in Patients with Heart Failure       Following Acute Myocardial Infarction, IND#51,780 (EPHESUS study).

2001 - March 2004; Co-Investigator at VA Pittsburgh Healthcare System, PA. Warfarin and Antiplatelet Therapy in Chronic Heart Failure (WATCH).

2001-2004; Co-Investigator at VA Pittsburgh Healthcare System, PA. Defibrillators   in Nonischemic Cardiomyopathy Treatment Evaluation Trial (DEFINITE Trial).

Dec 2001 to Feb 2007; Co-Investigator at VA Pittsburgh Healthcare System, PA.   Radiofrequency Cardio ablation for Atrial Fibrillation with Medtronic Cardioblate RF Ablation Surgical Handpiece.

February 2004 -November 2004. Co-Investigator at VA Pittsburgh HealthcareSystem, PA; A- Heft (African-American Heart Failure Trial; NDA#20-727 by Nitromed)    (No recruitment done as study was over before drugs arrived)

Feb 2005- Feb 2007: Co-Investigator at VA Pittsburgh Healthcare System, PA;   The RESTOR-MV Clinical Trial: Randomized Evaluation of a Surgical Treatment for Off-Pump repair of mitral valve.

January 2005- Feb 2007Co-Investigator VA Pittsburgh Healthcare System, PA.  Genetic Risk Assessment of Defibrillator Events in Collaboration with UPMC

January 2005 to December 2006 - Co-Investigator at VA Pittsburgh Healthcare System, Fusion II Trial  (Follow Up Serial Infusions of Natrecor for the Management of Patients with Heart  Failure); SCIOS, Inc.; 2005- Co- investigator- Merlin-TIMI 36 (Metabolic Efficiency with Ranolazine for less ischemia in Non- ST elevation acute coronary syndromes)

March 2006 to Feb 2007 - Co- investigator ATHENA: A placebo -controlled  double- blind parallel arm Trial to access the efficacy of dronedarone 400 mg bid for the prevention if cardiovascular Hospitalization or death from any cause in patients with atrial fibrillation/ atrial flutter( AF/ AFL)

Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF). Sponsor: National Institute of Health. Principal investigator for Huntington VA Medical center, Huntington, West Virginia, May 2007 to May 2008.

A randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate cardiovascular outcomes during treatment with lixisenatide in type 2 diabetic patients after an Acute Coronary Syndrome

24 Randomized, double-blind, triple-dummy trial to compare the efficacy of otamixaban with Unfractionated Heparin + eptifibatide, in patients with unstable angina/Non ST segment Elevation Myocardial infarction scheduled to undergo an early invasive strategy.

Abstracts

David S, Machado C, Borell D, Heiter A, Moten M. Pnuemopericardial Tamponade Following Creation of a Pericardial Window.  Chapter Meeting, American College of Cardiology, Michigan, October 1991

Khan U, H Khalid P Adler Moten M Tako Tsubo Syndrome 174th Annual Meeting of Tennessee Medical Association,  Nashville, TN  Poster presentation April, 2009 ( recieved best poster award)

Khan, M., Khalid, H., Baqir, R., Moten, M., Weber, K. (2009, September). Central Pontine Myelinolysis Associated with Hypokalemia in Late Pregnancy. Oral Presentation presented at: Midwest Regional Meeting of Society of General Internal Medicine (SGIM); Chicago, IL

Thapa R,  Moten M Rate Dependent Left Bundle Branch Block  SGIM Southern Regional Meeting  February 2010, New Orleans, LA

Thapa R, Adler P, Moten M Poster presentation  Detection of abnormal origin of Left Main Coronary Artery by Transthoracic Echocardiogram  Sep 2009 at SGIM MidWest Regional Meeting, Chicago, IL

Khan, M., Khalid, H., Baqir, R., Moten, M.(2010, March). Right Atrial Abscess Related to the Wires of an Intra-Cardiac Pacemaker. Poster presented at: Mid-Atlantic Regional Meeting of Society of General Internal Medicine (SGIM); New York, NY

Khan, M., Khalid, H., Baqir, R., Moten, M.(2010, February). Paradoxical Embolism Caused by a Port-a-Cath Related Right Atrial Thrombus. Poster presented at: Southern Regional Meeting of Society of General Internal Medicine (SGIM); New Orleans, LA.

Khan, M., Khalid, H., Baqir, R., Moten, M. (2010, February). Post Electro-Cardioversion Cardiogenic Shock. Poster presented at: Southern Regional Meeting of Society of General Internal Medicine (SGIM); New Orleans, LA.

Khan, M., Khalid, H., Baqir, R., Moten, M.. (2009, November). Loculated Pericardial Effusion (Peicardial Cyst) with Regional Tamponade in a Patient with Felty's Syndrome. Poster presented at: Interim Meeting of American Medical Association; Houston, TX.

Khan, M., Khalid, H., Baqir, R., Moten, M., Weber, K. (2009, September). Conservative Management of Minoxidil Induced Massive Pericardial Effusion with an Early Tamponade. Poster presented at: Midwest Regional Meeting of Society of General Internal Medicine (SGIM); Chicago, IL.

Khan, M., Khalid, H., Baqir, R., Moten, M.. (2010, February). Non-Sustained Ventricular Tachycardia Induced by Valsalva Maneuver in a Patient with Non-Obstructive Hypertrophic Cardiomyopathy. Oral Presentation presented at: Southern Regional Meeting of Society of General Internal Medicine (SGIM); New Orleans, LA.

Robin Shah, Moten. M (2011 November) Constrictive Pericarditis a Possible Long-Term Complication of Chest Trauma.  Poster presentation at SGIM Denver meeting November 4^th 2011