Past Formal Seminars

FALL 2012

Sept 7	11:00 am	Eric J. Deeds, Ph.D. University of Kansas - Lawrence (hosted by Dr. Mark Fisher)	"The Dynamics of Assembly in Biological Networks"
Sept 14	11:00 am	Donald Jacobs, Ph.D. University of North Carolina at Charlotte (hosted by Dr. Aron Fenton)	"Interrelationships Between Protein Stability, Flexibility and Dynamics"
Sept 21	11:00 am	Rajasingh Johnson, Ph.D., HCLD University of Kansas Medical Center (hosted by Dr. Mark Fisher)	"Reprogramming of Somatic Cells and Therapy"
Sept 28	11:00 am	Paul Sorgen, Ph.D. University of Nebraska Medical Center (hosted by Drs. Joseph Fontes and Alexey Ladokhin)	"Characterization of the Structure and Intermolecular Interactions between the Connexin32 Carboxyl-terminal Domain and the Protein Partners SAP97 and Calmodulin"
Oct 5	11:00 am	Adam Krieg, Ph.D. University of Kansas Medical Center (hosted by Dr. Mark Fisher)	"Hypoxic Regulation of Histone Demethylases Mediates Cellular Response to the Tumor Microenvironment"
Oct 12	11:00 am	Xiaogang Li, Ph.D. University of Kansas Medical Center (hosted by Dr. Jim Calvet)	"Epigenetic regulators and autosomal dominant polycystic kidney disease"
Oct 19*	11:00 am	Andrew L. Lee, Ph.D. University of North Carolina at Chapel Hill (hosted by Dr. Aron Fenton) note location change to 1027 Orr Major	"Insights into mechanisms of protein allostery from dynamics and NMR"
Oct 26	11:00 am	Fan Dong, M.D., Ph.D. University of Toledo (hosted by Dr. Joseph Fontes)	"Towards understanding of Gfi1 acts in hematopoiesis; the significances of its interaction with Miz-1 and the mechanism of its down regulation by p53"
Nov 2	11:00 am	Quyen Hoang, Ph.D. Indiana University School of Medicine (hosted by Dr. Mark Fisher)	"Mechanisms of genetics and envrionmental toxins in Parkinson's disease"
Nov 9*	1:00 PM	Heidi E. Hamm, Ph.D. Vanderbilt University Medical Center (hosted by Dr. Gerald Carlson) note location AND Time change: 1 pm, and Lied Auditorium	"New insights into mechanisms of receptor-mediated G protein activation"
Nov 13	11:00 am	James Bowie, Ph.D. UCLA-DOE Institute for Genomics & Proteomics (hosted by Dr. Alexey Ladokhin) NEW DAY: Tuesday, Nov 13th NEW LOCATION: Beller Conf Ctr	"How do membrane proteins fold?"
Nov 16	11:00 am	Elizabeth Komives, Ph.D. University of California San Diego (hosted by Dr. Antonio Artiques)	*"Functional Consequences of Intrinsic Disorder in the NFkB-IkB Interaction"*
Nov 23	11:00 am	No Seminar - Thanksgiving Holiday
Nov 30	11:00 am	Paul H. Axelsen, M.D. University of Pennsylvania School of Medicine (Hosted by Dr. Alexey Ladokhin)	*"Oxidative Stress, Lipid Membranes, and Protein Misfolding in Alzheimer's Disease"*
Dec 7	11:00 am	Brian S. J. Blagg, Ph.D. University of Kansas - Lawrence (hosted by Dr. Mark Fisher)	"Hsp90 inhibitors: past, present and future"
Dec 14	11:00 am	Thomas M. Ryan, Ph.D. University of Alabama at Birmingham (hosted by Dr. Ken Peterson)	*"Humanized Models of Beta Thalassemia Major & Taking the R out of RBC"*

SPRING 2012

Jan 13	11:00 am	Heather Desaire, Ph.D. University of Kansas - Lawrence (hosted by Dr. Chad Slawson)	"Enabling Technologies for Glycopeptide Analysis and Application to HIV vaccine development"
Jan 27	11:00 am	Lu Chen Graduate Student Dept. of Biochemistry & Molecular Biology	"The combinatorial nature of building chromatin remodeling machineries"
Feb 10	11:00 am	Moriah Beck, Ph.D. Wichita State University (hosted by Dr. Liskin Swint-Kruse)	"Structure and crosslinking mechanism of palladin's novel actin binding domain"
Feb 17	11:00 am	Subhash Naik Graduate Student - Biochemistry University of Kansas Medical Center	"Proteostasis and the kinetic aspects of misfolding diseases"
Feb 24	11:00 am	Alan S. L. Yu, MB, BChir. University of Kansas Medical Center (hosted by Dr. James Calvet)	"Structure-function studies of claudins, tight junction membrane proteins that regulate paracellular permeability"
Mar 9	11:00 am	Christopher J. Fischer, Ph.D. University of Kansas - Lawrence (hosted by Dr. Mark Fisher)	"Unravelling the kinetics of nucleosome repositioning"
Mar 16	11:00 am	Jeroen Roelofs, Ph.D. Kansas State University (hosted by Dr. Mark Fisher)	"Mechanism of chaperone-assisted assembly of the proteasome regulatory particle"
Apr 6	11:00 am	Michael Bulger, Ph.D. Univ of Rochester Medical Ctr (hosted by Dr. Ken Peterson)	"Enhancers and Hyperactylated Domains in Erythroid-Specific Gene Loci"
Apr 13	11:00 am	Mingui Fu, Ph.D. University of Missouri - Kansas City (hosted by Dr. Joe Fontes)	"Regulation of Inflammation and Immune Homeostasis by MCPIP1"
Apr 20	11:00 am	Patrick Frantom, Ph.D. University of Alabama (hosted by Dr. Aron Fenton)	"Allosteric Regulation of alpha-Isopropylmalate Synthase from Mycobaterium tuberculosis by L-Leucine"
Apr 27	11:00 am	Bryce V. Plapp, Ph.D. University of Iowa (hosted by Dr. Fenton)	"Alcohol dehydrogenase Dynamics and Catalysis"
May 4	11:00 am	George Vielhauer, Pharm.D./Ph.D. University of Kansas Cancer Center (hosted by Dr. Mark Fisher)	"Development of C-terminal Hsp90 inhibitors for the treatment of cancer"
May 11	11:00 am	Maria Kurnikova, Ph.D. Carnegie Mellon University (hosted by Dr. Alexey Ladokhin)	"Molecular Modeling of how structure facilitates function in membrane proteins"

FALL 2011

Sept 9	11:00 am	Candice S. Klug, Ph.D. Medical College of Wisconsin (hosted by Dr. Alexey Ladokhin)	"Effects of two key nucleotide binding domain mutations on the functional dynamics of the bacterial lipid flippase MsbA"
Sept 16	11:00 am	Qi Chen, Ph.D. University of Kansas Medical Center (hosted by Dr Liskin Swint-Kruse	"Pro-oxidant vitamin C: a promising role in cancer treatment?"
Sept 30	11:00 am	Kelly Tatchell, Ph.D. Louisiana State University (hosted by Dr. Ken Peterson)	"TOR Complex 2 regulates Lpl1/Autora B function via the GlcPP1 phosphatase"
Oct 7*	11:00 am	Michael L. Gross, Ph.D. Washington University in St. Louis (hosted by Dr. Aron Fenton)	"Applications of Mass-Spectrometry-Based Footprinting (H/DX and FPOP) to Aggregating Proteins)
Oct 21	11:00 am	Lesa J. Beamer, Ph.D. University of Missouri - Columbia (hosted by Dr. Swint-Kruse)	"Connecting structure, dynamics, and conformation change to enzyme function: studies of bacterial phosphohexomutase"
Oct 28	11:00 am	Richard R. Burgess, Ph.D. University of Wisconsin - Madison (hosted by Dr. Mark Fisher)	"One-second isolation/immunoprecipitation of weak protein complexes using a microfluidic IFAST device"
Nov 4	11:00 am	Judith Davie, Ph.D. Southern Illinois University School of Medicine (hosted by Dr. Joseph Fontes)	"Deciphering the role of interferon gamma andCIITA in myogenesis"
Nov 11	11:00 am	CANCELED. Speaker rescheduled to March 9, 2012
Nov 18*	11:00 am	Richard W. Hanson, Ph.D. Case Western Reserve University School of Medicine (hosted by Dr. Carlson)	"Born to run; the story of the PEPCK-Cmus mouse"
Dec 2	11:00 am	Danny R. Welch, Ph.D. University of Kansas Medical Center (hosted by Dr. Gerald Carlson)	"Metastasis Suppressors: Genetics, Epigenetics and the Tumor Microenvironment"
Dec 9	11:00 am	Gerald Hart, Ph.D. Johns Hopkins University School of Medicine (hosted by Dr. Chad Slawson)	"Extensive Crosstalk Between Phosphorylation and O-GlcNAcylation: Critical Roles in Diabetes, Alzheimer's Disease and Cancer"
Dec 16	11:00 am	Junpeng Deng, Ph.D. Oklahoma State University (hosted by Dr. Aron Fenton)	"IL18 and IL18BP in autoimmune and poxvirus infection"

SPRING 2011

Jan 14	11:00 am	Andrew Herr, Ph.D. University of Cincinnati College of Medicine (hosted by Dr. Todd Holyoak)	"Molecular basis for metal ion-induced intercellular adhesion in Staphylococcal biofilms"
Jan 21	11:00 am	Gerald Wyckoff, Ph.D. University of Missouri - Kansas City (hosted by Dr. Liskin Swint-Kruse)	"Bioinformatics and Evolution; A view from behind the monitor"
Jan 28	11:00 am	Colin Thorpe, Ph.D. University of Delaware (hosted by Dr. Mark Fisher)	"Making Protein Disulfide Bonds - Oxidative Folding in a Muddle"
Feb 4	11:00 am	David D. Weis, Ph.D. University of Kansas - Lawrence (hosted by Dr. Aron Fenton and Dr. Antonio Artigues)	"Investigation disordered proteins with D/D exchange and mass spectrometry"
Feb 18	11:00 am	Xiaolan Yao, Ph.D. University of Missouri - Kansas City (hosted by Dr. Alexey Ladokhin)	"Estimation of available free energy in a LOV-Ja photoswitch"
Mar 4	11:00 am	Troy Johnson Graduate Student	"PEPCK and catalysis: The fundamentals"
Mar 11	11:00 am	Christopher Vakoc, Ph.D. Cold Spring Harbor Laboratory (hosted by Dr. Kenneth Peterson)	"Epigenetics of Malignant Hematopoiesis"
Mar 25	11:00 am	Alex Moise, Ph.D. University of Kansas - Lawrence (hosted by Dr. Todd Holyoak)	"Identification of a novel retinoid-processing enzyme involved in the regulation of lipid metabolism"
Apr 1	11:00 am	Bin Deng, Graduate Student, Zhu lab	"Structural basis of inter-domain electron transfer in Ncb5or"
Apr 8*	11:00 am	John S. Olson, Ph.D.* Rice University (hosted by Dr. Swint-Kruse) NOTE: this seminar will be in 1027 Orr-Major	"NO Dioxygenation Globin Evolution, and Recombinant Hb-based Blood Substitutes"
Apr 15	11:00 am	Anton A. Komar, Ph.D. Cleveland State University (hosted by Dr. Joseph Fontes)	"Protein Folding on the Ribosome: When the Protein Folding Code Meets the Genetic Code"
Apr 22	11:00 am	Michael Baldwin, Ph.D. University of Missouri - Columbia (hosted by Dr. Mark Fisher)	"Unique Ganglioside Recognition Strategies of Clostridial Neurotoxins"
Apr 29	11:00 am	David L. Bain, Ph.D. University of Colorado - Denver (hosted by Dr. Aron Fenton)	"Towards a Quantitative Understanding of the Human Steroid Receptors: The Role of Energetics"
May 6*	11:00 am	Xiuxia Du, Ph.D. University of North Carolina at Charlotte (hosted by Dr. Owen Nadeau) NOTE: this seminar will be in 1027 Orr Major	"Xlink-Identifier: An Automated Data Analysis Platform for Confident Identifications of Chemically Cross-Linked Peptides Using Tandem Mass Spectrometry"
May 13	11:00 am	Pablo Sobrado, Ph.D. Virginia Tech (hosted by Dr. Aron Fenton)	"Mechanistic studies of UDP-galatopyranose mutases from eukaryotic human pathogens"

FALL 2010

Sep 10	11:00 am	Jed N. Lampe, Ph.D. University of Kansas Medical Center (hosted by Dr. Mark Fisher)	"Cytochrome P450 Protein-Ligand Interactions revealed through 2D MNR and Molecular Dynamic Simulations"
Sep 17	11:00 am	Lukas Tamm, Ph.D. University of Virginia (hosted by Dr. Alexey Ladokhin)	"Reconstitution of SNARE mediated Fusion on the Millisecond Timescale"
Sep 24	11:00 am	Christopher H. Lowrey, M.D. Dartmouth-Hitchcock Medical Center (hosted by Dr. Kenneth Peterson)	"Pharmacologic Induction of Fetal Hemoglobin Via Cell Stress Signaling Pathways; What Doesn't Kill Red Cells May Make Them Stronger"
Oct 8	11:00 am	Gloria Borgstahl, Ph.D. University of Nebraska Medical Center (hosted by Dr. Swint-Kruse)	"Identification of the DNA binding domains of Replication Protein A that recognize G-quadruplex DNA"
Oct 22	11:00 am	Please Note: Dr. David Weis' seminar has been canceled. It is rescheduled to Feb. 4, 2011.
Oct 29	11:00 am	Hiroo Katayama Graduate Student Dept of Biochemistry and Molecular Biology	"Anthrax toxin protective antigen: cell entry, transition to the pore, and translocation"
Nov 5	11:00 am	Marie Trudel, Ph.D. Institute de Recherches Cliniques de Montreal, University of Montreal (hosted by Dr. Jim Calvet and Dr. Kenneth Peterson)	"Signaling Mechanisms in Human ADPKD: Insights from Pkd1 Mouse Models"
Nov 12	11:00 am	James C. Lee, Ph.D. University of Texas Medical Branch (hosted by Dr. Aron Fenton)	"Structural and Functional Landscapes in the Allosteric Regulation CRP"
Nov 19	11:00 am	Peter V. Cornish, Ph.D. University of Missouri - Columbia (hosted by Dr. Aron Fenton)	"Single molecule investigation of ribosome dynamics and function"
Nov 26	11:00 am	No seminar - Thanksgiving Holiday
Dec 3	11:00 am	Doug English, Ph.D. Wichita State University (hosted by Dr. Alexey Ladokhin)	"Catanionic Surfactant Mixtures: Biotechnological Applications for a Common Class of Molecules"
Dec 10	11:00 am	Thomas M. Yankee, Pharm.D., Ph.D. University of Kansas Medical Center (hosted by Dr. Mark Fisher)	"Gads-dependent signaling pathways and thymic selection"

Spring 2010

Date	Time	Speaker	Title
Jan 22	11:00 am	David Davido, Ph.D. University of Kansas - Lawrence (hosted by Dr. Mark Fisher)	"Determining sites on and domains in the HSV-1 immediate-early protein ICPO that affect virus-host interactions"
Jan 29	11:00 am	Yang Zhang, Ph.D. University of Michigan (hosted by Dr. Mark Fisher)	"Progress and challenges in protein structure prediction"
Feb 5	11:00 am	Jay Unruh, Ph.D. Stowers Institute for Medical Research (hosted by Dr. Alexey Ladokhin)	"Measurements of Molecular Interactions In Vivo Using Fluorescence Correlation Methods"
Feb 12	11:00 am	Rathnam Chaguturu, Ph.D. University of Kansas - Lawrence (hosted by Dr. Kenneth Peterson)	canceled rescheduled on April 7
Feb 19*	11:00 am	Philip R. Hardwidge, Ph.D. University of Kansas Medical Center (hosted by Dr. Liskin Swint-Kruse)	"Bacterial Effector Binding to Ribosomal Protein S3 Subverts NF-kappaB Function"
Feb 26 *	11:00 am	Donald H. Burke University of Missouri - Columbia (hosted by Dr. Joseph Fontes)	"Universtalist and specialists: Inhibition specificity of anti-HIV-1 aptamers
Mar 5	11:00 am	Soumen Paul, Ph.D. University of Kansas Medical Center (hosted by Dr. Jospeh Fontes)	"Histone Chaperone in Endothelial Gene Regulation"
Mar 19	11:00 am	Spring Break - No Seminar
Mar 26	11:00 am	Stephen D. Levene Ph.D. University of Texas at Dallas (hosted by Dr. Kenneth Peterson)	"Loop-mediated regulation by lac repressor: does DNA supercoiling play a role?"
Apr 2	11:00 am	Aaron L. Lucius, Ph.D. University of Alabama at Birmingham (hosted by Dr. Aron Fenton)	"Mechanisms of Assembly and Polypeptide Translocation Catalyzed by the E.coli ClpA Molecular Motor "
Apr 7 *	11:00 am Beller Conf Ctr	Rathnam Chaguturu, Ph.D. University of Kansas - Lawrence (hosted by Dr. Kenneth Peterson) rescheduled from February 12th	"High Throughput Screening Laboratory at KU: One Stop Source for all Your Drug Discovery Needs"
Apr 9	11:00 am	Student Research Forum - No Seminar
Apr 16	11:00 am	Wiliam Skach, M.D. Oregon Health & Science University (hosted by Dr. Alexey Ladokhin)	"Cellular Mechanisms of Membrane Protein Folding"
Apr 23	11:00 am	Wonpil Im, Ph.D. University of Kansas - Lawrence (hosted by Dr. Alexey Ladokhin)	"Mechanisms and Energetics of Protein/Peptide Interactions in Biological Membranes"
May 14	11:00 am	Michael T. Henzl, Ph.D. University of Missouri - Columbia (hosted by Dr. Liskin Swint-Kruse)	"Impact of the Unliganded State on Parvalbumin Divalent Ion Affinity"
May 21	11:00 am	S. Walter Englander, Ph.D. University of Pennsylvania Medical School (hosted by Dr. Antonio Artigues)	"How proteins do all of that as seen by hydrogen exchange. GroEL function. Protein folding. Lipoprotein structure."

Fall 2009

Date	Time	Speaker	Title
Sept 4	11:00 am	Anne Hinderliter, Ph.D. University of Minnesota, Duluth (hosted by Dr. Aron Fenton)	"Signaling at the Membrane: toward quantitative understanding"
Sept 11	11:00 am	Katsura Asano, Ph.D. Kansas State University (hosted by Dr. Joseph Fontes)	"Translation factor control of stress signaling response: The case of Int6/elFe and rRNA mutations"
Sept 18	11:00 am	No Seminar - Faculty Retreat
Sept 25	11:00 am	Joseph J. Falke, Ph.D. University of Colorado (hosted by Dr. Alexey Ladokhin)	"Leukocyte chemotaxis: Molecular mechanisms of membrane targeting at the leading edge membrane"
Oct 2	11:00 am	Karl Rozman, Ph.D. University of Kansas Medical Center (hosted by Dr. Wilfred Arnold)	"Hormesis or the Effects of Low Doses of Toxic Agents"
Oct 9	11:00 am	Florence Tama, Ph.D. University of Arizona (hosted by Dr. Mark Fisher)	"Coarse-grained modeling to characterize structure of biological molecules from low-resolution data"
Oct 23	11:00 am	Mohammad Ayoub Mir, Ph.D. University of Kansas Medical Center (hosted by Dr. Mark Fisher)	"Hantavirus nucleocapsid protein guides transcript and translation initiation of viral mRNA"
Nov 6	11:00 am	Simon H. Friedman, Ph.D. University of Missouri, Kansas City (hosted by Dr. Mark Fisher)	"Patterning of gene expression in cell monolayers using Light Activated RNA Interference (LARI)"
Nov 13	11:00 am	Matthew Goering, Graduate Student University of Kansas Medical Center	"Cohesin and Chromosome Cohesion: Implications for DNA Double-Strand Break Repair"
Nov 20	11:00 am	Eric Milot, Ph.D. University of Montreal (hosted by Dr. Ken Peterson)	"The combination of GAT-1 and Ikaros favors gene silencing in erythroid cells"
Nov 27	11:00 am	No Seminar - Thanksgiving Holiday
Dec 11	11:00 am	Aaron Gottschalk, Graduate Student University of Kansas Medical Center	"Modulation of Chromatin Structure by Snf2-like ATPases and Parp1"
Dec 18	11:00 am	Edward B. Stephens, Ph.D. University of Kansas Medical Center (hosted by Dr. Mark Fisher)	"The APOBEC3 Protein Family: An Innate Immune System Against Retroviruses"

SPRING 2009
(click on highlighted names to be directed to a speaker's website)

Date	Time	Location	Speaker	Title
Jan 30	11:00 am	B018 SON	Todd Holyoak, Ph.D. University of Kansas Medical Center	"Loops and Lids. The role of dynamics in PEPCK catalysis"
Feb 6	11:00 am	1050 SON	Liang Tang, Ph.D. University of Kansas - Lawrence (hosted by Mark Fisher)	"Virus meet Bacterium"
Feb 13	11:00 am	1050 SON	David R. Setzer, Ph.D. University of Missouri - Columbia (hosted by Joesph Fontes)	"Accidental Insights into the Mechanism of Transcription Activation"
Feb 20	11:00 am	1050 SON	John Karanicolas, Ph.D. University of Kansas - Lawrence (hosted by Mark Fisher)	"Designing Protein-Protein Interfaces"
Feb 27	11:00 am	1050 SON	Stephen J. Brandt, M.D. Vanderbilt University Medical Center (hosted by Kenneth Peterson)	"Emerging functions of LIM domain-binding and single-stranded DNA-binding proteins"
Mar 6	11:00 am	1050 SON	Cynthia M. Dupureur, Ph.D. University of Missouri St. Lous (hosted by Aron Fenton)	"Mechanistic and Biophysical Studies of Esterases"
Mar 13	11:00 am	B018 SON	Yuqi Wang, Ph.D. Saint Louis University (hosted by James Calvet)	"Ubiquitination and G Protein Signaling in Yeast"
Mar 20	11:00 am		No Seminar - Spring Break
Mar 27	11:00 am	1050 SON	Jim Bann, Ph.D. Wichita State University (hosted by Mark Fisher)	"The nine rings: The role of histidine protonation in anthrax toxin pore formation"
Apr 3	11:00 am	1050 SON	Ben Weaver, Graduate Student Dissertation Defense	"Regulatory Mechanisms of Slc39a4 (ZIP4) and Slc39a5 (ZIP5) "
Apr 10	11:00 am		No Seminar - Student Research Forum
Apr 17	11:00 am	1050 SON	Angie Rizzino, Ph.D. University of Nebraska Medical Center (hosted by Joseph Fontes)	"Sox transcription factors function as molecular rheostats to control the fate of pluripotenet stemcells"
Apr 24	11:00 am	1023 OM	P. Scott Hefty, Ph.D. University of Kansas - Lawrence (hosted by Liskin Swint-Kruse)	"Developmental Gene Regulation in Chlamydia: Role and Mechanisms of an Atypical OmpR Response Regulator, ChxR"
May 1	11:00 am	B018 SON	Mitchell J. Weiss, MD, Ph.D. University of Pennsylvania (hosted by Kenneth Peterson)	"Transcriptional Control of Erythro-Megakaryocytic Differentiation"
May 8	11:00 am	B018 SON	Dennis R. Livesay, Ph.D. University of North Carolina - Charlotte (hosted by Liskin Swint-Kruse)	"Elucidating protein family sequence/structure/function relationships: from biophysics to empiricism and back"
May 15	11:00 am	B018 SON	Harvey F. Fisher, Ph.D. University of Kansas Medical Center	"Experimental Application of the Second Rule of Transient-State Isotope Effects to the Phenylalanine Dehydrogenase Reaction"

FALL 2008

Date

Time

Speaker

Title

Sep 5	11:00 am	David Thomas, Ph.D. University of Minnesota	"Spectrocopic Probes of Muscle Protein Structural Dynamics"
Sep 12	11:00 am	Preston Hensley Pfizer Global Research & Development	"Drug Discovery and the New Pharma-University Interface"
Sep 19 *	11:00 am	Jeffrey L. Brodsky, Ph.D. University of Pittsburg, PA	"Using Yeast to Defin the Molecular Basis of Protein Conformational Disease"
Sep 26	11:00 am	Suzanne Scarlata, Ph.D. Stony Brook University, New York	"Cellular Regulation of Phospholipase C-beta Enzymes through G Proteins"
Oct 3	11:00 am	Indranil Biswas, Ph.D. University of Kansas Medical Center	"Role of Two-component signal transduction systems in Streptococcus Mutans Virulence"
Oct 10	11:00 am	Patricia L. Clark, Ph.D. University of Notre Dame	"Co-translational Folding of an Aggregation-Prone Protein"
Oct 31	11:00 am	Jack F. Kirsch, Ph.D. University of California	"Directed Evolution and Rational Design Approaches to Shifting Enzyme Paralog Function"
Nov 7		No Seminar - Faculty Research Day
Nov 14	11:00 am	Paul Fitzpatrick, Ph.D. Texas A&M University	"Catalytic and Regulatory Mechanisms of Tyrosine Hydroxylase"
Nov 21	11:00 am	Philippe Prochasson, Ph.D. University of Kansas Medical Center	"Chromatin and transcriptional regulation by the HIR Complex and SWI/SNF chromatin remodeling"
Nov 28		No Seminar - Thanksgiving Holiday
Dec 5	11:00 am	Duane C. Eichler, Ph.D. University of South Florida	"Why a Urea Cycle Enzyme Regulates Vascular Endothelial Nitric Oxide Production"

SPRING 2008

Date

Time

Speaker

Title

Jan 4	11:00 am	Lane K. Christienson, Ph.D. University of Kansas Medical Center	"MicroRNAs and Ovarian Function"
Jan 11	11:00 am	James Kranz, Ph.D. Johnson & Johnson PRD	"Thrombin Conformational Diversity: Influence on Ligand Binding Energetics and Drug Discovery"
Jan 18	11:00 am	Luis A. Marky, Ph.D. University of Nebraska Medical Center	"Sherlock Holmes's Adventures with Nucleic Acids"
Jan 25	11:00 am	Julia Zeitlinger, Ph.D. Stowers Institute	"Transcriptional regulatory networks in the early Drosophilia embryo"
Feb 1	11:00 am	Bruno Hagenbuch, Ph.D. University of Kansas Medical Center	"The multispecific organic anion transporters OATP1B1 and 1B3"
Feb 8	11:00 am	Steven Parnell, Ph.D. University of Kansas Medical Center	"Signaling Pathways in Polysystic Kidney Disease"
Feb 15	11:00 am	Susan Egan, Ph.D. University of Kansas - Lawrence	"AraC family Transcription Activators as Anti-bacterial Targets"
Feb 22	11:00 am	Mark Richter, Ph.D. University of Kansas - Lawrence	"Generating Rotational Torque in the World's Tiniest Rotary Motor"
Feb 29	11:00 am	Xiaogang Li, Ph.D. Stowers Institute	"Autosomal Dominant Polycystic Kidney Disease: Understanding the Mechanisms, Discovering Treatments"
Mar 7	11:00 am	Gerd Blobel, MD, Ph.D. Univ. of Pennsylvania School of Medicine	"Navigating through chromatin: Regulation of hematopoietic development by transcription factor GATA-1"
Mar 14	11:00 am	Kyoungtae Kim, Ph.D. Missouri State University	"Yeast Endoctosis: Roles of Actin Capping Protein and Dynamin-like Protein Vps1"
Mar 21	11:00 am	No Seminar - Spring Break
Mar 28	11:00 am	Ben Weaver Graduate Student	"The Genetics of Essential Metal Homeostasis during Development"
Apr 4	11:00 am	TBA	TBA
Apr 11	11:00 am	No Seminar - Student Research Forum
Apr 18	11:00 am	Anne Kenworthy, Ph.D. Vanderbilt University	"Structure and dynamics of membrane rafts"
Apr 25	11:00 am	John J. Tanner, Ph.D. University of Missouri - Columbia	"Structural biology of proline catabolism"
May 2	11:00 am	Alexander Beeser, Ph.D. Kansas State University	"Advancing selective in vivo Pak1 protein kinase inhibitors as translational therapeutics"

FALL 2007

Sep 7	11:00 am	Russ Middaugh, Ph.D. University of Kansas - Lawrence	The Polyanion World
Sep 14	11:00 am	Mark Wilson, Ph.D. University of Nebraska	Hammer or Swiss-Army Knife?: Structural Conservation and Functional Diversity the DJ-1 Superfamily
Sep 21	11:00 am	Barsanjit Mazumder, Ph.D. Cleveland State University	Translational Silencing in Monocytes: Role of Ribosomal Protein, Initiation Factors, and Signal to Resolve Inflammation
Sep 28	11:00 am	Jennifer Laurence, Ph.D. University of Kansas - LawrenceTBA	Assessing the Structure-Activity Relationship of the Phosphatase of Regenerating Liver PRL-1
Oct 5	11:00 am	Betty S. Pace, M.D. University of Texas - Dallas	Genomic Approches to Elucidate Mechanisms for Fetal Globin Gene Regulation
Oct 12	11:00 am	Tomasz Kordula, Ph.D. Virginia Commonwealth University School of Medicine	Tissue-specific gene regulation in astrocytes and glioma cell
Oct 19	11:00 am	Lee M. Graves, Ph.D. University of North Carolina - Chapel Hill	Control of Pyrimidine Metabolism by Protein Kinases
Oct 26	11:00 am	Raymond Camahort Graduate Student	Building centromeric chromatin: Studying how budding yeast find the needle in the haystack
Nov 2	11:00 am	Russell Swerdlow, M.D. University of Kansas Medical Center	Mitochondria and Alzheimer's Disease
Nov 9	11:00 am	TBA	TBA
Nov 16	11:00 am	Eduardo Perozo, Ph.D. University of Chicago	Structural basis of K+ channel activation and inactivation gating
Nov 23	11:00 am	No Seminar - Thanksgiving Holiday
Nov 30	11:00 am	Lisa Timmons, Ph.D. University of Kansas - Lawrence	ABC transporters are required for efficient RNAi in Caenorhabditis elegans
Dec 7	11:00 am	Brian M. Baker University of Notre Dame	T cell receptor recognition of antigen: more questions than answers?
Dec 14	11:00 am	Ali Shilatifard, Ph.D. Stowers Institute	Chromatin Modifications by Methylation and Human Leukemia

SPRING 2007

Date

Time

Speaker

Title

Jan 5	11:00 am	Chen-Yong Lin, Ph.D. Gerogetown Medical Center	"Deregulation of matriptase in human carcinomas"
Jan 12	11:00 am	Rong Li, Ph.D. Stowers Institute of Research	"In-vivo biochemical analysis of dynamic protein interactions in the MAP kinase signaling cascade"
Jan 19	11:00 am	Brian V. Geisbrecht, Ph.D. University of Missouri -Kansas City	"Using Structure to Unravel the Mechanism of Staphylococcal Complement Inhibitors"
Jan 26	11:00 am	Arthur Cooper, Ph.D. Weill Medical College of Cornell Univ.	"Role of Transglutaminases in Neurodegeneraive Diseases"
Feb 2	11:00 am	Maria Schumacher, Ph.D. Univ of Texas M.D. Anderson Cancer Ctr	"Peptide Self-Assembly and Pore Formation in Membranes: The Use of Combinatorial Chemistry as a Learning Tool"
Feb 9	11:00 am	William C. WImley, Ph.D. Tulane University Health Services Center	"Peptide Self-Assembly and Pore Formation in Membranes: The Use of Combinatorial Chemistry as a Learning Tool"
Feb 16	11:00 am	Yoshi Azuma, Ph.D. University of Kansas - Lawrence	"Role of SUMO modification in vertebrate mitosis"
Feb 23	11:00 am	Jorg Bungert, Ph.D. University of Florida	"Locus Control Region Mediated Recruitment of Transcription Complexes to the Beta-Globin Gene Locus"
Mar 2	11:00 am	D. Wayne Bolen, Ph.D. University of Texas, Medical Branch	"Nature's emphasis on the peptide backbone in osmolyte-induced protein folding/unfolding"
Mar 9	11:00 am	Mark S. Hargrove, Ph.D. Iowa State University	"Structural highlights in the evolution of oxygen transport in plants"
Mar 16	11:00 am	Dagmar Ringe, Ph.D. Brandeis University	"Iron mediated control of virulence: the diptheria tox repressor"
Mar 23	11:00 am	No Seminar - Spring Break
Mar 30	11:00 am	Tom Roche, Ph.D. Kansas State University	"Regulation of pyruvate dehydrogenase kinase (PDK) and restriction of PDK activity in treating diabetes, heart disease, and cancer"
Apr 6	11:00 am	No Seminar
Apr 13	11:00 am	Stuart Smith, Ph.D., D.Sc. Children's Hospital Oakland Research Institute co-sponsored with Dept. of Medicine	"Structural & functional analysis of the fatty acid biosynthetic enzymes in mammalian mitochondria: Coupling of lipogenic and lipoylation pathways"
Apr 20	11:00 am	David L. Brautigan, Ph.D., University of Virginia School of Medicine	"Opposition to Cytokine Signaling by Novel Protein Phosphatases"
****SPECIAL Apr 25	SEMINAR**** 12 noon Lied Aud.	Jie Wu, Ph.D. University of Florida College of Medicine	"Regulation of the Shp2 Protein Tyrosine Phosphatse in cell Signaling and Oncogenesis"
Apr 27	11:00 am	Henrik Dohlman, Ph.D. University of North Carolina - Chapel Hill	"G protein signaling at the endosome"
May 4	11:00 am	Andrei B. Belousov, Ph.D. University of Kansas Medical Center	"Glutamate-dependent neuronal plasticity in the CNS: chemical and electrical synapses"

FALL 2006

Date

Time

Speaker

Title

Sep 8	11:00 am	Wolfram R. Zuckert, Ph.D. University of Kansas Medical Center	"Rules and Regulators of Lipoprotein Secretion in Borrelia Spirochetes"
Sep 15	11:00 am	C. Nick Pace, Ph.D. Texas A&M University Health Science Ctr	"Fine Tuning Protein Stability and the pK Values of Ionizable Groups "
Sep 22	11:00 am	Richard N. Armstrong, Ph.D. Vanderbilt University	"Structural and Functional Genomics of Antibiotic Resistance"
Sep 29	11:00 am	Canceled
Oct 6	11:00 am	Brian S. J. Blagg, Ph.D. University of Kansas - Lawrence	"Managing the Hsp90 Protein Folding Process with Small Molecules"
Oct 13	11:00 am	Curt Hagedorn, M.D. University of Kansas Medical Center	"Role of an RNA Binding Protein in Epithelial Cancer Progression"
Oct 20	11:00 am	Joesph Lutkenhaus, Ph.D. University of Kansas Medical Center	"Regulating Bacterial Cell Division"
Oct 27	11:00 am	Marco Blanchette, Ph.D. University of California - Berkeley	"Functional Genomic Analysis of Drosophilia Alternative Splicing Factors"
Nov 3	11:00 am	Peter Rowe, Ph.D. University of Kansas Medical Center	"Mineralization and bone-renal pathways: the harmonious struggle of the living skeleton"
Nov 10	11:00 am	Michael Petris, Ph.D. University of Missouri - Columbia	"Inflammation is a novel regulator of copper homeostasis"
Nov 17	11:00 am	Stuart Smith, Ph.D., DSC Children's Hospital Oakland Rsrch Inst co-sponsored with Dept of Medicine	"Structural & functional analysis of the fatty acid biosynthetic enzymes in mammalian mitochondria: Coupling of lipogenic &lipoylation pathways"
Nov 24	11:00 am	No Seminar - Thanksgiving Holiday
Dec 1	11:00 am	Canceled due to Inclement Weather
Dec 8	11:00 am	No Seminar - Department Event
Dec 15	11:00 am	Robert Fuller, Ph.D. University of Michigan Medical Center	"Specificity and inhibition of eukaryotic proprotein processing proteases"

Spring 2006

Date

Time

Speaker

Title

Jan 13	11:00 am	Gregory Petsko, Ph.D. Brandeis University	On the Origin of Enzymatic Species: How New Enzymes Evolve from Old Ones
Jan 20	11:00 am	R. John Collier, Ph.D. Harvard Medical School	Anthrax Toxin: Mechanism of Membrane Translocation
Jan 27	11:00 am	Jay Vivian, Ph.D. University of Kansas Medical Center	Genetic Screens in Mouse Embryonic Stem Cells
Feb 3	11:00 am	Paul E. Smith, Ph.D. Kansas State University	Computer Simulation of the Delta Opioid Receptor and Delta Opioid Receptor Selective Peptide Agonists
Feb 10	11:00 am	Canceled
Feb 17	11:00 am	Page Geiger, Ph.D. University of Kansas Medical Center	Exercise Training in the Prevention of Insulin Resistance and Type 2 Diabetes: A Cellular Approach
Feb 24	11:00 am	Vincent J. Hilser, Ph.D. University of Texas Medical Branch	What's in a Protein Ensemble
Mar 3	11:00 am	Dorothy Beckett, Ph.D. University of Maryland	Regulating the Regulators; Control of Transcription Repression Complex
Mar 10	11:00 am	A. L. Burlingame, Ph.D. University of California San Francisco	The Challenge of Defining Protein Postranslational Complexity Using Mass Spectrometry
Mar 17	11:00 am	John M. Tomich, Ph.D. Kansas State University	"Redesigning Nature: Studies on New Channel-Forming Sequences Derived from the Second Transmembrane Segment of the Glycine Receptor-Subunit"
Mar 24	11:00 am	No Seminar - Spring Break
Mar 31	11:00 am	Hao Zhu, Ph.D. University of Kansas Medical Center	"NCB5OR, Oxidative Stress and Diabetes"
Apr 7	11:00 am	Roberto De Guzman, Ph.D. University of Kansas - Lawrence	"NMR Studies of Proteins Involved in Bacterial and Viral Pathogenesis"
Apr 14 Lied Aud.	11:00 am	C. Robert Matthews, Ph.D. University of Massachusetts Medical School Note change of location to Lied Auditorium	"Are protein folding mechanisms better conserved than their amino acid sequences? The roles of topology and sequence in controlling the folding mechanisms of TIM barrel proteins"
Apr 21	11:00 am	Joyce A. Lloyd, Ph.D. Virginia Commonwealth University	"Globin Gene Regulation: Bottom-Up and Top-Down Approaches"
Apr 28	11:00 am	Malin M. Young, Ph.D. Sandia National Laboratories	"Protein Structural characterization using chemical cross-linking, mass spectrometry and modeling"
May 5	11:00 am	Canceled
May 12	11:00 am	Jackob Moskovitz, D.Sc. University of Kansas - Lawrence	"The methionine sulfoxide reductase system and its role in antioxidant defense and survival"
May 19	11:00 am	Andrew D. Robertson, Ph.D. University of Iowa	"Structural Consequences of Insertions Among Ubiquitin-Like Proteins

Fall 2005

Date

Time

Speaker

Title

Sept 9	11:00 am	Jinxi Wang, M.D., Ph.D. Orthopedics, University of Kansas Medical Center	Enhancement of Skeletal Repair by Biochemical & Molecular Means
Sept 16	11:00 am	Henry Miziorko, Ph.D. University of Missouri - Kansas City	HMG-CoA Synthase: Functional Correlations and a Reversal of Expectations
Sept 23	11:00 am	Michael Washburn, Ph.D. Stowers Institute, Kansas City	Quantitative Proteomic Analysis via MudPIT
Sept 30	11:00 am	Li Wang, Ph.D. University of Kansas Medical Center	'Orphan' but not lonely: how much can nuclear receptor SHP do?
Oct 7	11:00 am	No Seminar - SOM Faculty Retreat
Oct 14	11:00 am	John Laity, Ph.D. University of Missouri-Kansas City	Are we full of Zinc? Binding and structural studies of metalloregulatory domains from MTF-1 and Zap1
Oct 21	11:00 am	George Reed, Ph.D. University of Wisconsin	Encolase. A Jewel in the Crown of Glycolysis
Oct 28	11:00 am	T. Chris Gamblin, Ph.D. University of Kansas - Lawrence	Modeling Neurodegenerative Tauopathies In Vitro
Nov 4	11:00 am	David Toft, Ph.D. Mayo Clinic	Chaperoning Cell Regulatory Proteins through Hsp90
Nov 11	11:00 am	Yeon-Kyun Shin, Ph.D. Iowa State University	Intermediates in SNARE-Mediated Membrane Fusion
Nov 18	11:00 am	Madeline A. Shea, Ph.D. University of Iowas	Calmodulin Regulation: A Tale of Two Domains
Nov 25	11:00 am	No Seminar - Holiday
Dec 2	11:00 am	Joseph Fontes, Ph.D. Faculty Candidate	The ZXD family: Novel regulators of MHC II transcription
Dec 5	8:30 - 10:00 a.m.	Jeremy Sanford, Ph.D. Faculty Candidate note new location: Lied Auditorium	Getting the message: RNA binding proteins and post-transcriptional gene expression
Dec 6	9:00 am	Steve Patrick, Ph.D. Faculty Candidate note new location: 1014 Orr Major	Biochemical Processing of Cisplatin-DNA Interstrand Cross-links (ICLs)
Dec 9	11:00 am	Felix Koberling PicoQuant, Berlin, Germany Special Seminar	Time-resolved Confocal Fluorescence Microscopy: Novel Technical Features and Applications for FLIM, FRET and FCS"
Dec 16	11:00 am	Scott Warder, Ph.D. Abbott Labs	Discovery of Protein Markers for Pharmaceutical Drug Development

Spring 2005

Date

Time

Speaker

Title

Jan 14	11:00 am	Jonathan Silberg, Ph.D. Rice University	"On the conservative nature of protein recombination"
Jan 21	11:00 am	Sue Jaspersen, Ph.D. University of Colorado, Boulder	"Yeast Centrosomes: Structure, Duplication and Function"
Jan 28	11:00 am	Chris Lorson, Ph.D. University of Missouri - Coloumbia	"The Role of Survival Motor Neuron (SMN) in the Development of Spinal Muscular Atrophy"
Feb 4	11:00 am	Michal Zolkiewski, Ph.D. Kansas State University	"Structure and Function of ClpB: a Protein-Disaggregating Molecular Chaperone"
Feb 11	11:00 am	Emily Scott, Ph.D. University of Kansas-Lawrence	"Structure and Function of Cytochrome P450s involved in Xenobiotic Metabolism"
Feb 18	11:00 am	Xiao-Qiang (Sean) Yu, Ph.D. University of Missouri - Kansas City	"Lectins in innate immune responses of an insect"
Feb 25	11:00 am	Deborah S. Wuttke, Ph.D. University of Colorado	"Tying up the Ends: Recognition of Single-Stranded DNA at Telomeres"
Mar 11	11:00 am	Mario Ernesto Rivera-Laos, Ph.D. University of Kansas - Lawrence	"Heme Oxygenase in Pathogenic Bacteria: Insights from Magnetic Resonance Investigations of the Active Site"
Mar 18	11:00 am	Yu-Jui Yvonne Wan, Ph.D. Dept of Pharmacology, Toxicology & Therapeutics, KUMC	"Functional Analysis of Retionoid X receptor alpha in Hepatocyte"
Apr 1	11:00 am	Don G. Ennis, Ph.D. University of Louisiana - Lafayette	"Development of a Mutagenesis Assay in Transgenic Animals: Investigations of Chronic Infections and Carcinogenesis"
Apr 8	11:00 am	Frederick Sachs, Ph.D. Hughes Center for Single Molecule Biophysics	"Mechanosensitive ion channels: from bench to bedside"
Apr 15	11:00 am	Richard Honzatko, Ph.D. Iowa State University	"Ligand Cooperativity in Fructose-1,6-bishoshpatase"
Apr 22	11:00 am	Philip J. Thomas, Ph.D. UT Southwester Medical Center at Dallas	"Cystic Fibrosis: Disease of Altered Protein Folding"
Apr 29	11:00 am	Thomas Nowak, Ph.D. University of Notre Dame	"Fundamental Steps in Pyruvate Kinase: Phosphoryl Transfer and Enolpyruvate Protonation"
May 6	11:00 am	Patrick Loria, Ph.D. Yale University	"Conversation and Control of Enzyme Dynamics for Optimal Catalysis"
May 13	11:00 am	Jill Trewhella, Ph.D. Dept of Chemistry, University of Utah,	Structural Themes and Variations in Kinase Activation and Targeting

Fall 2004

Date

Time

Speaker

Title

Sept 10	11:00 am	Liskin Swint-Kruse, PhD. Dept of Biochemistry & Molecular Biology, KUMC	"Tools to identify functionally relevant fine details in protein structure"
Sept 24	10:00 am Lied Aud.	Carey Johnson, PhD Dept of Chemistry University of Kansas - Lawrence	"Single-Molecule Spectroscopy of Calcium Signaling: Dynamics and Target Interactions of Calmodulin"
Oct 8	11:00 am	David Mount, Ph.D. University of Arizona	"Cancer Bioinformatics: support for the discovery of new drugs and diagnostic tools"
Oct 15	11:00 am	Rolf Jakobi, Ph.D. Kansas City University of Medicine and Biosciences	"The Role of p21-Activated Protein Kinase2 in Cell Survival and Cell Death"
Oct 22	11:00 am	Karen G. Fleming, Ph.D. Johns Hopkins University	"Membrane Protein Interactions: Thermodynamics in the Role of Sequence Motifs"
Oct 29	11:00 am	Edith Chang, Ph.D. Kansas City University of Medicine and Biosciences	"The Role of cyclooxygenase 2 in Cell Survival, Cell Motility and Colon Cancer Development"
Nov 5	11:00 am	Anthony L. Fink, Ph.D. University of California, Santa Cruz	"The molecular basis for ß-synuclein fibrillation: Implications for Parkinson's Disease"
Nov 12	11:00 am	Greg Reinhart, Ph.D. Texas A&M	"Using Fluctuation Spectroscopy to Study Protein-Protein Interactions"
Nov 19	11:00 am	Art Johnson, Ph.D Texas A&M	"Maintenance of Membrane Integrity by Ribosomes, BiP, and Translocons during ER Protein Trafficking"
Nov 26	11:00 am	No Seminar Thanksgiving Holiday
Dec 3	11:00 am	John Robertson, Ph.D. Dept of Pharmacology & Toxicology, KUMC	"Caspase-2-mediated engagement of the mitochondrial apoptotic pathway"
Dec 10	11:00 am	Sarah Bondos, Ph.D. Rice University	"Integrating Information: Hox Proteins physically and genetically interact with proteins from an array of cellular systems"
Dec 17	11:00 am	Audrey Lambs, Ph.D. University of Kansas-Lawrence	"Siderophore Biosynthesis by Pseudomonas aeruginosa"

Last modified: Dec 17, 2012

Events

Information for:

Academics

Department of Biochemistry and Molecular Biology

Past Formal Seminars

"The Dynamics of Assembly in Biological Networks"

"Interrelationships Between Protein Stability, Flexibility and Dynamics"

"Reprogramming of Somatic Cells and Therapy"

"Characterization of the Structure and Intermolecular Interactions between the Connexin32 Carboxyl-terminal Domain and the Protein Partners SAP97 and Calmodulin"

"Hypoxic Regulation of Histone Demethylases Mediates Cellular Response to the Tumor Microenvironment"

"Epigenetic regulators and autosomal dominant polycystic kidney disease"

"Insights into mechanisms of protein allostery from dynamics and NMR"

"Towards understanding of Gfi1 acts in hematopoiesis; the significances of its interaction with Miz-1 and the mechanism of its down regulation by p53"

"Mechanisms of genetics and envrionmental toxins in Parkinson's disease"

"New insights into mechanisms of receptor-mediated G protein activation"

"How do membrane proteins fold?"

Spring 2006

Fall 2005

Spring 2005

Fall 2004