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Stanley R. Nelson, MD
Professor Emeritus
Anatomy and Cell Biology
M.D.: 1959, Tulane University, New Orleans, LA
Postdoctoral: Washington University, St. Louis, MO
Early research centered on the changes in energy metabolism that are associated with brain damage. This extended into methods of measuring brain edema and the effectiveness of drugs in treating this condition. More recently, the role of free radicals in brain damage was studied and in particular the manner in which transition metals (iron and copper) propagate free radicals in these injuries.
Recent Publications
- Pazdernik TL, Emerson MR, Cross R, Nelson SR and Samson FE. Soman-induced seizures: Limbic activity, oxidative stress and neuroprotective proteins. J. Appl. Toxicol. 21: 2001.
- O'Brien- Ladner A, Nelson SR, Murphy WJ, Blumer BM and Wesselius LJ. Iron is a regulator component of human IL-1b production. Am. J. Respir. Cell Mol. Biol. 23:112-119, 2000.
- Nelson SR, Pazdernik TL and Samson FE. Measurement of loosely-bound iron in brain regions using redox cycling and salicylate. Cell and Mol. Biol. 46:649-655, 2000.
- Emerson MR, Nelson SR, Samson FE and Pazdernik TL. A global hypoxia preconditioning model: neuroprotection against seizure-induced specific gravity changes (edema) and brain damage in rats. Brain Res. Protocols 4:360-366, 1999.
- Emerson MR, Nelson SR, Samson FE and Pazdernik TL. Hypoxia preconditioning attenuates brain edema associated with kainic acid-induced status epilepticus in rats. Brain Res. 825:189-193, 1999.
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