Jill Hamilton-Reeves, PhD, RD, LD

Assistant Professor
Department of Dietetics and Nutrition


Professional Background

A registered and licensed dietitian with doctoral training in translational and clinical nutrition science, Jill Hamilton-Reeves, PhD, RD, LD, teaches in the graduate programs in the Department of Dietetics and Nutrition. In addition to serving as instructor for DN 819 Scientific Writing in the Nutritional Sciences, she also provides nutrition-focused lectures to first-year students in the School of Medicine's MD core curriculum, including CORE 815 Cardiopulmonary, CORE 820 Gastrointestinal, and CORE 825 Renal and Endocrine. Her other joint appointments at KU include internal medicine, hematology/oncology and urology, urologic oncology.

Hamilton-Reeves is an associate member of the Cancer Prevention Program in the University of Kansas Cancer Center. She has practiced as a registered dietitian since 2004 and has been an NSCA-certified personal trainer since 1999. For more than 15 years, she has been active in presenting to academic and community audiences about healthy lifestyles and chronic disease prevention.

Academic Background

Hamilton-Reeves earned her bachelor’s degree in exercise science from Creighton University, Omaha, Neb., in 1999. She then completed her didactic education in dietetics from University of Nebraska, Lincoln, Neb., in 2001. She went on to the University of Minnesota, St. Paul, Minn., where she completed her dietetic internship in 2004 and earned her doctorate in Human Nutrition in 2006.

Hamilton-Reeves worked as an assistant professor at St. Catherine University in St. Paul, Minn., from 2007-2011. She joined the KU Medical Center as a faculty member in the Department of Dietetics and Nutrition in September 2011.

Research Focus

Research by Hamilton-Reeves is focused on nutrition and cancer prevention, management, and survivorship, with specific attention on genitourinary cancers. Hamilton-Reeves is evaluating nutrition strategies to improve patient outcomes after bladder cancer surgery.

In addition, she provides nutrition expertise in collaboration on several studies with researchers from urologic oncology, endocrinology, hematology/oncology, and the Kidney Institute. These projects include a diet intervention in patients with autosomal dominant polycystic kidney disease, and a project evaluating the effects of soy intake on cardiovascular disease biomarkers in patients with subclinical hypothyroidism. Hamilton-Reeves partners with the bioinformatics faculty to pursue her interest in medical informatics tools for data-driven research. For more information on research efforts, please visit the Exercise, Diet, Genitourinary, & Endocrinology (EDGE) Research Laboratory.

Curriculum Vitae PDF document

PubMed (graphic)See my publications on PubMed

Research Lab

Graduate students training with Hamilton-Reeves obtain clinical and translational research experiences with one-on-one patient care, applied statistical analyses, wet lab bench science skills, and introductory medical informatics. In their work at the Exercise, Diet, Genitourinary, & Endocrinology (EDGE) Research Laboratory, they also acquire significant writing experience for both technical and lay audiences.


Selected Current and Recent Projects

The augmentation of chemotherapy with a low carbohydrate diet in bladder cancer
Hamilton-Reeves (Co-Investigator)
Institutional Review Grant
American Cancer Society
The goal of this project is to study the effects of a diet very low in carbohydrates in combination with standard bladder cancer chemotherapy in an orthotopic mouse model of bladder cancer metastasis

Development of prediction models for bladder cancer recurrence using clinical, pathological, and molecular data
Hamilton-Reeves (Co-Investigator)
Cancer Prevention Pilot Project Award
The University of Kansas Cancer Center
The goal of this project is to develop and validate a nomogram for predicting short-term risk of recurrence among non–muscle-invasive bladder cancer using patient-level clinical and pathological data, and to investigate the extent to which incorporating blood-based DNA methylation biomarkers improves prediction accuracy over nomograms based on clinical and pathological information only.

Preventing the progression of cachexia in bladder cancer patients
Hamilton-Reeves (Principal Investigator)
Frontiers KL2 Clinical and Translational Mentored Career Development Award
Frontiers HICTR: Heartland Institute for Clinical and Translational Research
The goal of this project is to determine how surgery alters the number and phenotype of myeloid-derived suppressor cells and determine if immune modulating supplementation prevents the up regulation of myeloid-derived suppressor cells, serum cytokines, and blocks the T helper 2 dominated response to surgery and thus reduced radical cystectomy-induced cachexia.

Caloric Restriction to Reduce Prostate Cancer Risk
Clinical Pilot Program
Hamilton-Reeves (Principal Investigator) 
Frontiers Pilot and Collaborative Studies Funding Program
Frontiers HICTR: Heartland Institute for Clinical and Translational Research
The goal of this project is to test the impact of weight loss on prostate cancer biomarkers in the primary and secondary prostate cancer prevention populations.

Energy Balance for Prostate Cancer Prevention and Survivorship
Hamilton-Reeves (Principal Investigator)
Cancer Prevention Pilot Project Award
The University of Kansas Cancer Center
The goal of this project is to customize a weight loss approach for men, a group where weight control has not been well-studied, in the primary and secondary prostate cancer prevention populations.

Effect of soy protein intake on gene transcripts in subclinical hypothyroid participants
Hamilton-Reeves (Principal Investigator)
Next Gen Sequencing Pilot Grant
NIH National Center for Advancing Translational Science and Kansas Intellectual and Developmental Disabilities Research Center
The project is expected to identify the effects of soy protein consumption on subclinical hypothyroidism by comparing gene transcripts in the blood of participants consuming soy protein to those consuming a protein-matched placebo.

Impact Advanced Recovery in Radical Cystectomy Patients
Hamilton-Reeves (Principal Investigator)
Nutrition Research Grant
Nestlé HealthCare
The goal of this project is to better understand the catabolic response to radical cystectomy surgery in bladder cancer patients and direct efforts to reduce the burden of postoperative complications, including malnutrition, infections, readmission rates, and hospital length of stay.

Improving Radical Cystectomy Patient Outcomes through Nutrition
Hamilton-Reeves (Principal Investigator)
Institutional Review Grant
American Cancer Society
The goal of this project is to better understand the immune response to radical cystectomy surgery in bladder cancer patients and direct efforts to reduce the burden of postoperative complications.

Effect of Soy Intake on CVD in Subclinical Hypothyroid Patients
Hamilton-Reeves (Principal Investigator)
Soy Nutrition Institute
The project is expected to determine the reversibility of the effects of soy intake in patients who progress from subclinical to overt hypothyroidism in response to isoflavone-rich soy protein upon discontinuation of soy intake and to determine the impact of soy on cardiovascular disease biomarkers in all patients.

A New Diet for Autosomal Dominant Polycystic Kidney Disease
Grantham, Hamilton-Reeves (Co-Investigator)
Clinical Pilot Program
Pilot and Collaborative Studies Funding Program and the KUMC Research Institute
The goal of this project is to develop a diet low in net acid precursors to reduce urinary net acid excretion.

Completed Projects

Mechanistic effects of soy intake on the pathogenesis of prostate cancer
Hamilton-Reeves (Principal Investigator)
Pilot Program
University of Kansas Cancer Center
The goal of this project is to lead to a better understanding of the biological response to soy with respect to hormonal status and cell signaling within the prostate tissue.

Multi-Foods for the Prevention of Prostate Cancer
Hamilton-Reeves (Principal Investigator)
Faculty Research and Scholarly Activities Grant
St. Catherine University
The goal of this project was to develop and plan a clinical study to submit a comprehensive and multidisciplinary NIH grant proposal. 

Vitamin D and Medication Interactions Review
Hamilton-Reeves (Principal Investigator)
Faculty Research and Scholarly Activities Grant
St. Catherine University
The goal of this project was to conduct a systematic review of the literature to evaluate the extent to which medications affect Vitamin D status or the extent to which vitamin D alters drug metabolism. 

Meta-analysis of the hormonal effects of soy on testosterone
Hamilton-Reeves (Principal Investigator)
Soy Nutrition Institute, United Soybean Board
The goal of this project was to conduct a meta-analysis in order to determine if isoflavones exert estrogen-like effects in men by lowering bioavailable testosterone, the effects of soy protein or isoflavone intake on testosterone, sex hormone binding globulin (SHBG), free testosterone, and free androgen index (FAI) in men were evaluated.

SoyCaP: Soy and Prostate Cancer Prevention
Hamilton-Reeves (Principal Investigator)
US Department of Defense
The goal of this project was to evaluate the effects of soy phytoestrogens on reproductive hormones and prostate tissue markers of cell proliferation and androgen action in men at high risk of prostate cancer.

Last modified: Mar 03, 2014

Jill Hamilton-Reeves

Contact

Jill Hamilton-Reeves, PhD, RD, LD
Assistant Professor

P: (913) 588-7650
F: (913) 588-8946
jhamilton-reeves@kumc.edu

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