Job Mart - Updated 12 September 2002

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Chairman, Department of Radiobiology, Uniformed Services University of the Health Sciences and Scientific Director, Armed Forces Radiobiology Research Institute.  The Uniformed Services University of the Health Sciences (USUHS) School of Medicine and the Armed Forces Radiobiology Research Institute (AFRRI) invite applications and nominations for a dual appointment as Chairman, Department of Radiobiology (USUHS) and as Scientific Director (AFRRI). An individual is sought with an M.D. or Ph.D. degree with a distinguished reputation and extensive state-of-the-art basic and applied research and teaching experience in radiation biology, health physics or a related discipline. Applicants must have outstanding interpersonal skills and managerial experience with the potential to lead a multimillion-dollar applied research and development program working with a multidisciplinary staff of scientists and technicians focused on medical countermeasures against radiation injuries. Applicants must also be able to establish and lead a new Department of Radiobiology, recruit new faculty and graduate students, develop curricula leading to the M.S. and Ph.D. degrees, and attract outside funding to support basic research as well as manage the daily operations of the department within the School of Medicine. Review of applications will begin on July 1, 2001. Letters of nomination and application should be sent to: Search Committee, Department of Radiobiology/Scientific Director, c/o Dr. G. David Ledney, Chairman, Radiation Medicine Department, Armed Forces Radiobiology Research Institute, Bldg 42, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603. USUHS and AFRRI are equal employment employers. Additional information is available on the Uniformed Services University of the Health Sciences website (http://www.usuhs.mil/chr/vacancies.htm).

Resident Associate Chief of Research, Radiation Effects Research Foundation: The U.S. National Academy of Sciences (NAS) is seeking a Resident Associate Chief of Research for the Radiation Effects Research Foundation (RERF) in Hiroshima, Japan. RERF is a cooperative US-Japan research foundation with approximately 290 employees in laboratories in Hiroshima and Nagasaki, Japan. The Foundation is funded by the Government of Japan, through the Ministry of Health and Welfare, and by the U.S. Government, through the NAS with funds from the Department of Energy (DoE). RERF is managed by citizens of the two countries. The position of Associate Chief of Research is a senior leadership position with responsibility to assist in the direction of the research activities conducted at RERF on the long-term follow-up of late health effects among the survivors of the atomic bombs. The Associate Chief of Research assists three RERF Directors, all of whom live in Japan, in the day-to-day management of the Foundation. Qualified candidates for this position must be U.S. citizens and have an M.D. or Ph.D with extensive experience in basic research (genetics, molecular biology, cellular biology, epidemiology, immunology, etc.) and management of multi-disciplinary research programs. The Associate Chief of Research is an employee of the United States National Academy of Sciences and RERF. The salary will be commensurate with experience and will be supplemented by relocation, housing, and cost-of-living benefits. Typical NAS appointments are for two years with possible reappointment. Please send your resume and the names and addresses of at least three references to: Dr. Evan B. Douple, Board on Radiation Effects Research, (NAS 342-ED), National Academy of Sciences, 2101 Constitution Avenue, NW, Washington, D.C. 20418. Fax: (202)334-1639; e-mail: edouple@nas.edu

Faculty Appointment in the Department of Oncology, McGill University: Applications are invited for a newly created position at the Assistant Professor level. The successful applicant should have a Ph.D. and/or M.D. degree and postdoctoral experience, and be prepared to develop an independent, extramurally funded research program within 2-3 years of appointment. He/she will also be asked to participate in teaching radiation biology to graduate students and radiation oncology residents. Research interests of the Radiation Biology Group include development and application of methods for prediction of tumor response to radiation treatment, both from the point of view of the genetic profile of the cancer cell and the characterization of the tumor micro-environment, DNA damage and repair and the interaction of radiation with Growth Factor Receptors and signal transduction processes. The laboratory has recently received funding for major equipment purchase and generous start-up funds and laboratory space are available for a new investigator. Montreal is home to a large research community in the health and natural sciences and extensive opportunities exist for collaboration in basic and clinical research, both at McGill and at other centres in the area. For further information contact Dr Shirley Lehnert, Radiation Oncology, Montreal General Hospital, 1650 Cedar Avenue, Montreal, Quebec H3G 1A4, CANADA. Telephone: (514)934-1934, ext. 44161; Fax: (514)934-8220; e-mail: shirley.lehnert@mcgill.ca

Health Physicist/Radiochemist: Lawrence Berkeley National Laboratory has an immediate opening for a Health Physicist/Radiochemist to provide full time support to the National Tritium Labeling Facility (NTLF). The incumbent will carry out research on methods to optimize tritiation process efficiency, containment, and safety while reducing environmental emissions and waste. The incumbent will also support NTLF activities to meet EH&S regulatory compliance requirements. This individual will work with community and regulatory stakeholder groups, providing information about laboratory activities. The complete position description is posted at http://www.lbl.gov/CJO/ehs011084ehs.html

Faculty Appointment in Molecular Radiobiology, Taussig Cancer Center and The Lerner Research Institute, Cleveland Clinic Foundation: The Departments of Radiation Oncology and Cancer Biology invite outstanding applications for a faculty position at the ASSISTANT PROFESSOR level. The successful candidate, with a Ph.D. and/or M.D. degree and postdoctoral experience, is expected to develop an independent extramurally funded research program. Generous start-up funds, modern laboratory space in the newly opened Taussig Cancer Center, and access to oustanding core facilities in The Lerner Research Institute are provided. Areas of interest include: DNA damage response, cell cycle control, and other fundamental research which may lead to new approaches to radiation treatment. Candidates should be able to communicate effectively at the interface of basic science and clinical problems and be involved in basic and clinical collaborative projects. Those interested can learn more about our programs by visiting our Websites: http://www.lerner.ccf.org/depts/cancerbio.html and http://www2.clevelandclinic.org/radonc/radoncccf.htm. Applications including a curriculum vitae, summary of research interests, and three letters of recommendation should be sent to: Alex Almasan, Ph.D., Department of Cancer Biology NB-40, 9500 Euclid Avenue, Cleveland, OH 44195; Fax (216)445-6269, e-mail: almasaa@ccf.org (only inquiries). The Cleveland Clinic Foundation is an Equal Opportunity Employer.

Radiation Biologist, Oregon Health Sciences University Department of Radiation Oncology: The School of Medicine and Oregon Cancer Center at Oregon Health Sciences University (OHSU) invite applications for a tenure track position at the Assistant or Associate Professor level in the Department of Radiation Oncology and membership in the OHSU Oregon Cancer Center. Applicants must have a Ph.D. or MD/Ph.D. and have sufficient research background and experience to develop and maintain an independent, extramurally funded program in radiation biology and to teach radiation biology to radiation oncology residents and radiation therapy students. Successful applicants will be expected to organize a translational research program of radiation biology research, and encouraged to develop collaborative activities with both clinical research groups and basic scientists involved in fields of DNA damage and repair, control of radiation-induced molecular responses, stem cell biology, apoptotic signaling pathways, Fanconi anemia protein function, chaperone/co-chaperone function, cell cycle checkpoint control, or other related fields now well-represented on our campus. Please send curriculum vitae, a brief statement of research interest, and names of three references to: John M. Holland, M.D., OHSU Department of Radiation Oncology, L337, 3181 S.W. Sam Jackson Pk Rd, Portland, OR 97201-3098. Telephone: (503)494-8756; e-mail: hollanjo@ohsu.edu. The Oregon Health Sciences University is an Affirmative Action/Equal Opportunity Employer. Women and minorities are encouraged to apply.

Radiation Biologists, Wake Forest University School of Medicine, Department of Radiation Oncology. The Department of Radiation Oncology and the Comprehensive Cancer Center of Wake Forest University (CCCWFU) invite applications for 2 tenure track positions at the Assistant or Associate Professor level in the Radiation Biology Section, Department of Radiation Oncology and membership in the CCCWFU. Applicants should hold a Ph.D. or MD/Ph.D. and will be expected to develop independent extramurally funded research programs. Excellent start-up funds and outstanding laboratory space in the newly opened Nutrition Research Center are available. Areas of ongoing research include: translational regulation of gene expression by hypoxic stress; gene therapy; naturally occurring chemopreventative compounds as novel radiation sensitizers; role of oxidative stress in normal tissue injury and in tumor response to anticancer therapies. Successful applicants will be encouraged to develop collaborative activities within the CCCWFU research programs, including DNA Damage and Cellular Defense, Cell Growth and Survival, Cancer Control and Clinical Research. Please send curriculum vitae, a statement of research interests and names of three references to Mike Robbins, Ph.D., Section Head, Radiation Biology, Department of Radiation Oncology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157. Telephone: (336) 716-6110; e-mail: mrobbins@wfubmc.edu. Wake Forest University School of Medicine is an Affirmative Action/Equal Opportunity Employer. Women and minorities are encouraged to apply.

Tenure-Track Faculty Position, Radiological Sciences, Purdue University. The position is a full-time, tenure track, academic year, faculty appointment at the assistant professor level in the School of Health Sciences, Purdue University, a State University. Outstanding applicants will be considered for a higher faculty rank. Applicants in all areas of radiological science will be considered but preference will be given to those having expertise in medical physics (therapy or imaging) and/or and health physics, radiobiology, microdosimetry, or radioanalytical instrumentation. The successful applicant must be able to participate in courses dealing with the fundamentals of radioactivity, radiation interactions, radioisotope methodologies, radiobiology, and radiation protection. The applicant must have a Ph.D. or equivalent, and will be expected to maintain an externally funded research program and to supervise graduate students. Purdue is one of the top 10 universities in engineering and science and interdisciplinary research is highly valued and encouraged. Interested applicants should submit a letter of introduction which includes a statement of research interests and goals, a curriculum vita including a list of publications, past and current research funding, and the names, addresses, and telephone numbers of three references. Applications will be received and reviewed immediately and continue until the position is filled. Applications should be sent to Dr. George A. Sandison, Head and Chair, Search Committee, Purdue University, School of Health Sciences, West Lafayette, Indiana 47907-1338, Telephone: (765) 494-1419; e-mail: sandison@purdue.edu. (website: http://www.purdue.edu/HSCI/). Purdue University is an Affirmative Action/Equal Opportunity Employer.

ASSISTANT SCIENTIST S-1 (Two positions), Biology Department, Brookhaven National Laboratory. Heavy ion beamline scientists to provide expertise and support to radiobiology investigators at the Booster Accelerator Facility and Alternating Gradient Synchrotron at Brookhaven National Laboratory. Requires a Ph.D. in radiation biology, cell biology, or molecular biology; or related field and postdoctoral experience. Experience in cell culture and good communications skills and willingness to work with U.S. and international investigators is essential.  A strong background and/or experience in radiation biology and previous experience in accelerator-based radiobiology, or in carrying out research away from home institution are desirable. As part of a NASA-sponsored project, will join a team of heavy ion beamline scientists providing expertise, support and guidance to NASA-sponsored radiobiology investigators at the new Booster Accelerator Facility (http://server.ags.bnl.gov/bnlags/BAF/bafhome.htm) and at the Alternating Gradient Synchrotron (http://bnlstb.bio.bnl.gov/biodocs/nasa/nasa_ags.htmlx). This new facility will provide charged particles from protons to gold for irradiation of biological specimens. Extended and irregular hours may be required; must live locally to provide off-hours support to Users, and must be willing to travel to collaborating institutions, and national or international scientific conferences.  NIH, DOE, and NSBRI funding may be available for individual research on induction and repair of clustered DNA damages, including potential for participation in Heavy Ion Radiobiology program, under the direction of B. Sutherland [see Proc. Natl. Acad. Sci. U.S.A. (2000) 97:103; or Nucleic Acids Research (2002) 30:2800; or Radiation Research (2002) 157: 611]. For more information, contact Betsy Sutherland, E-mail: bms@bnl.gov; Telephone: (631) 344-3380; Fax: (631) 344-3407. To apply, send your C.V., description of your research experience and interests, a one-paragraph description of your qualifications for a beamline scientist position and names, addresses, telephone numbers and email addresses of at least three references to Dr. Betsy Sutherland, Building 463, Biology Department, Brookhaven National Lab, Upton, Long Island, New York 11973 or by e-mail to bms@bnl.gov. BNL is an equal opportunity employer; women and minorities are especially encouraged to apply.

Post-doctoral Position: Ottawa Regional Cancer Centre, Ottawa, Canada. Applications are invited for a newly-funded position at the Centre for Cancer Therapeutics at the Ottawa Regional Cancer Centre. The applicant will use a combination of DNA microarray and molecular biology approaches (PCR, transfection, antisense, immunofluorescent techniques) to investigate the genetic basis of cellular response to X-radiation. The other major interest in the group is investigating the applicability of chronomodulating chemoradiation treatments given to human tumor xenografts growing in mice. Assets: background in molecular biology and a recent Ph.D. in a biological/ biophysical science. Other preferred attributes: knowledge of cell culture, good analytical and communication skills. Interested applicants should contact: Cheng E. Ng, Ph.D., Ottawa Regional Cancer Centre, 503 Smyth Road, Ottawa, ON, K1H 1C4. Telephone: (613)737-7700 Ext. 6940, E-mail: Cheng.Ng@orcc.on.ca, Fax: (613)247-3524.

Post-doctoral Position: Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York. A position for a recent Ph.D. is available in our “Multimodality Biological Imaging of Cancer and Tumor Hypoxia” research group. Our long range goal is to develop non-invasive multi-modality imaging that yields biological information of human cancers in 3-dimensions (3D). The short-term objectives are to use NMR and PET for imaging tumor biology and hypoxia in rodent tumors and xenografts. In addition, pO2 levels will be directly measured in the same tumors, and tumor sections characterized to provide a biological basis for the NMR and PET images. All the 3D data sets of images and tumor sections will be spatially correlated with a stereotaxic reference system implanted around the rodent tumors and xenografts. This project integrates physics, chemistry, biology, engineering and computer sciences to study tumor biology and hypoxia. A background in cell biology and mammalian cell culture and experience with animal models is desirable.  For further information, contact Paul Burgman, E-mail: burgmanp@mskcc.org; phone: (212) 639-2843, or Jim Russell, E-mail: russellj@mskcc.org; phone (212) 639-2166. To apply, E-mail your C.V., description of research experience and names and addresses of three references.

Post-doctoral Position: Division of Experimental Therapy, The Netherlands Cancer Institute, Amsterdam. A postdoctoral position is available in the group of Adrian Begg, Experimental Radiotherapy, for a 4-year Dutch Cancer Society funded project entitled "Determinants of radiosensitivity in mammalian cells: elucidating mechanisms using a putative dominant negative to DNA polymerase beta" Required experience: molecular biology, preferably in DNA repair, but not essential. The project is aimed at elucidating basic mechanisms of radiosensitivity in mammalian cells (human and mouse), and is based on our finding of radiosensitiziation of human tumor cells by a putative dominant negative to DNA polymerase beta. In addition to improving understanding of genetic determinants of radiosensitivity, the long term goal is to look for intervention targets. The work will be carried out within a large cancer research institute with excellent core facilites and a wealth of experience in molecular and cell biology, and diagnostic and therapeutic oncology. For more information, contact Adrian Begg at: a.begg@nki.nl; Tel: +31-20-512-2036; FAX: +31-20-512-2050.

Post-Doctoral Position: Stanford University is seeking an individual to study radiation-induced apoptosis, oncogenes, ion channels/pumps, Calcium fluxes and signal transduction pathways. The applicant should have a working knowledge of basic molecular and cellular biological techniques. To apply, please send a curriculum vitae and the names of three references to Susan J. Knox, Ph.D., M.D., Dept. Radiation Oncology, Room A093, Stanford University Medical Center, 300 Pasteur Dr., Stanford, CA 94305. Fax: (650)725-8231; e-mail: knox@reyes.stanford.edu. Stanford University is an equal opportunity employer.

Post-Doctoral Position: The Edwin L. Steele Laboratory for Tumor Biology currently has openings in post-doctoral and faculty positions for outstanding applicants with diverse backgrounds including biomedical engineering, physics/biophysics, molecular pathology, mathematical modeling, immunology, molecular biology, cell biology, and physiology. For details visit http://steele.mgh.harvard.edu/steele/positions.html Questions regarding this request should be directed to Professor Rakesh Jain at (617)726-4083 or jain@steele.mgh.harvard.edu

Post-Doctoral Positions in Cellular/Molecular Biology, Massachusetts General Hospital/Harvard Medical School: Two post-doctoral positions are available immediately. One is to study radiation- and endogenous free radical-induced cell signaling pathways in cell and tissue explant systems. The project aims to determine the relationship between signaling pathways involved in the response of cells to low doses of ionizing radiation and those involved in oxidative stress responses. The radiation studies will involve using unique targeted radiation sources (microbeams) and will be done in collaboration with the Cell & Molecular Biophysics Group at the Gray Laboratory Cancer Research Trust, just outside London in the UK. It is expected that 50% of the position will be based at the Gray Lab as a visiting fellowship. The second position involves investigation of the pathways involved in induction of apoptosis by oxidative stress and thiol-containing compounds. The research project seeks further elucidation of an apparently novel apoptotic pathway elicited by thiols, that is independent of mitochondrial involvement. Both positions will suit a post-doctoral scientist with a background in cellular/molecular biology who has experience in cell signaling studies, particularly related to oxidative stress. A working knowledge of cell signal transduction and/or apoptosis pathways, oncogenes and in situ cytometry is essential. To apply, please send curriculum vitae and names and addresses of three references to Kathryn D. Held, Ph.D., Department of Radiation Oncology, Cox 302, Massachusetts General Hospital, Fruit Street, Boston, MA 02114. Fax: (617)724-8320; e-mail: kheld@partners.org. Massachusetts General Hospital/Harvard Medical School is an equal opportunity employer.

Post-Doctoral Position in DNA repair, Lawrence Livermore National Laboratory. A position for 2-3 years is available to produce and characterize knockout mutations in genes of the pathways of homologous recombination, base excision repair, and cell-cycle checkpoint functions in hamster CHO cells. This is an ongoing, highly interactive project involving several investigators. The construction of an arrayed CHO BAC-clone library has greatly simplified the cloning of hamster genes for preparing gene-targeting vectors. Our research is focussed on understanding molecular mechanisms of DNA repair pathways at the gene and protein level, and determining the quantitative contribution of genes and pathways in cellular responses to radiation damage. The studies involve techniques in molecular biology, cell culture, molecular genetics, and cytogenetics. Duties include participation in weekly meetings of the DNA Repair Group and presentation of results at national meetings. Background desired: Ph.D. degree and experience in molecular genetics, mammalian cell culture, and/or chromosome analysis; experience and knowledge of the literature in the field of DNA repair with emphasis on mammalian systems; ability to work with minimal supervision and to learn new techniques as need to accomplish defined goals. Contact: Larry H. Thompson (Team Leader of DNA Repair Group), BBR Program, L441, Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, CA 94551-0808, Telephone: (925)422-5658; Fax: (925)422-2282; e-mail: thompson14@llnl.gov

Post-Doctoral Position, University of Pennsylvania, Philadelphia. Position available on NIH funded PO1 to study cell cycle alterations after irradiation. The lab is interested in determining the effects of radiation on the progression from G2 into M and is exploring the effects of radiation on cyclin B1 expression, gene expression in general and G2 and mitotic checkpoints. We are also exploring strategies for using this information to design therapeutic agents. Please contact Ruth Muschel, MD, PhD, Rm 269 John Morgan Bld., 3620 Hamilton Walk, Philadelphia, PA 19104. Phone: (215)898-8401; Fax: (215)573-4243; e-mail: muschel@@xrt.upenn.edu

Post-Doctoral Position, University of Pennsylvania, Philadelphia. We have recently developed a novel strategy for studying metastasis involving direct visualization of tumor cells in the pulmonary circulation. This approach has led to a new model for metastasis (Nature Med 6: 100, 2000) that focuses upon the attachment of tumor cells to the pulmonary endothelium and the regulation of apoptosis thereafter. A postdoctoral position is available to use this new methodology to pursue the implications of the model. Please contact Ruth Muschel, MD, PhD, Rm 269 John Morgan Bld., 3620 Hamilton Walk, Philadelphia, PA 19104. Phone: (215)898-8401; Fax: (215)573-4243; e-mail: muschel@@xrt.upenn.edu

Post-Doctoral Fellowships in Radiation Research, New Jersey Medical School. Postdoctoral fellowships are available in an NIH funded group studying the biological effects of radiation. Research topics include: 1) effects of irradiated cells on unirradiated bystander cells, 2) biological effects of nonuniform distributions of radioactivity in mammalian tissue, and 3) development of computer models to predict biological effects of radioactivity. A variety of experimental approaches are employed in the research including cell culture, traditional cell survival and mutation assays, comet assay, flow cytometry, fluorescent activated cell sorting (FACS), western blots, and confocal microscopy. State of the art computing facilities are available for theoretical modeling. Candidates should have a recent doctoral degree in the biological sciences or experimental physics. Computer programming experience is desirable. Interested individuals are encouraged to speak with faculty and staff in the Department of Radiology, New Jersey Medical School: Roger W. Howell, Ph.D., Associate Professor of Radiology. Helene Z. Hill, Ph.D., Professor of Radiology. Edouard I. Azzam, Ph.D., Assistant Professor of Radiology. Anupam Bishayee, Ph.D., Post-doctoral fellow. Please send CV and a list of at least three references to: Roger W. Howell, Ph.D., Department of Radiology, MSB F-451, UMDNJ - New Jersey Medical School, 185 S. Orange Ave., Newark, NJ, 07103, USA. rhowell@umdnj.edu.

Post-doctoral position,  Duke University Medical Center. The Tumor Microcirculation Laboratory, Department of Radiation Oncology has a post doctoral position available for studies focused on oxygen transport in tumors. The laboratory seeks applicants who are motivated to work in a multidisciplinary environment with emphasis on team interactions to address complex issues in tumor microcirculatory physiology.  The purpose of the work is to examine the features of tumor physiology that lead to defective oxygen transport and to use this knowledge to: (1) understand microenvironmental control of gene expression and (2) design methods to ameliorate hypoxia. The general approach utilizes the combination of experimental measurements and theoretical models to examine issues of oxygen and other solute transport in tumor tissues.  Examples of methods that are currently in use in the laboratory include skin fold window chambers, phosphorescence lifetime imaging for pO2 measurement, bioluminescence imaging (for ATP, lactate and glucose concentration measurements in tissues), microelectrodes and confocal microscopy. In addition, the laboratory has tumor cell lines stably transfected with reporter genes to explore the relation between the microenvironment and gene regulation, in situ.  Applicants must have a PhD, MD, DVM or equivalent, appropriate experience and demonstrated ability to work independently as well as in a team environment. Duke University is an equal opportunity employer.  Applicants should send a C.V., names and addresses of three individuals willing to provide a recommendation and a personal statement to:  Mark W. Dewhirst, DVM, PhD; Director Tumor Microcirculation Laboratory; Box 3455; Duke University Medical Center; Durham, NC 27710.  Phone: (919)684-4180; Fax: (919)684-8718; e-mail: dewhirst@radonc.duke.edu. For further information see
http://www.radonc.duke.edu/department/academ/div/cancerbio/labs/tmcl/index.html

Post-doctoral positions in Molecular Genetics of Pulmonary Injury, M.D. Anderson Cancer Center. Positions are available for interested postdoctoral fellows to work on NIH funded research on the genetics of pulmonary injury. The laboratory uses recently developed tools and methodology for identifying genetic susceptibility loci regulating pulmonary injury after radiation and chemotherapeutic agents in well-established experimental mouse genetic models of pulmonary injury. Genotyping methodology, gene expression microarrays, and bioinformatic tools are used to identify regulatory genetic loci. Required experience includes a PhD or equivalent degree. Training in genetics, bioinformatics, genomics or pulmonary pathobiology is preferred. Interested individuals should send their resume and a letter supporting their candidacy to Dr. Elizabeth Travis, M. D. Anderson Cancer Center, 1515 Holcombe Blvd. – 066, Houston, TX 77030. Alternatively you may e-mail to etravis@mdanderson.org or fax to (713)794-5369. Training grant opportunities are available.

Post-doctoral Position in DNA Repair; Ontario Cancer Institute/Princess Margaret Hospital. A Post-Doctoral Fellow is required for a newly funded position to investigate the molecular basis of DNA-dsb repair in the carcinogenesis and therapeutic response of human prostate tissues. The successful applicant will join a research team with interests in mammalian cell-cycle checkpoint control, DNA repair and translational studies pertaining to the radioresponse of prostate cancer. In particular, the position will address the role of the homologous versus non-homologous pathway of DNA-double strand break repair in determining the response of stromal versus epithelial tissues to DNA damaging agents both in vitro, and in vivo, in model systems. Methodology may include flow cytomtery, cell transfection, immunofluorescent confocal microscopy, primary stromal and epithelial cell culture and DNA microarray analyses.The applicant should be Post-PhD or Post-MD/MD-PhD (with relevant research experience) and have a strong background in molecular biology (PCR-DNA sequencing, DNA/RNA/protein preparation/probing and cell transfection). A strong background in mammalian cell culture and prior experience with animal models is desirable. Salary will be comensurate with experience. Web-site: http://medbio.utoronto.ca/faculty/bristow.html   Please send curriculum vitae and research interests/accomplishments to: Dr. R. Bristow, MD, PhD, FRCPC; Assistant Professor (Univ. Toronto) and Associate Scientist (OCI); Princess Margaret Hospital-UHN; Department of Radiation Oncology; 610 University Avenue; Rm 5-923 Toronto, Ontario, CANADA M5G 2M9.  Phone: (416)946-2128; Fax: (416)946-4442; e-mail: rob.bristow@rmp.uhn.on.ca

Post-doctoral Positions; Thomas Jefferson University. A position is currently available on an N.I.H T32 Post Doctoral Training grant. The grant is about to complete the second year of this five-year cycle. It supports 5 post doctoral fellows. An announcement poster can be viewed at
http://www.kcc.tju.edu/Science/TrainingPrograms/DNAdamage.htm The goals of the training program emphasize the development of novel cancer treatment strategies using state of the art translation approaches. The training faculty is internationally renowned. The theme is "The Science of DNA Damage Response," specifically DNA repair, checkpoint activation, signal transduction, mechanisms of apoptosis and response modifiers. While the emphasis of research training is at the level of mechanisms and benchtop applications, trainees will have both a basic science and clinical mentor and will spend at least two weeks in medical oncology and radiation oncology during their preceptorship. Thomas Jefferson University is an equal opportunity employer. However, since this is a T-32 Training Grant, the U.S. Government mandates that all trainees be U.S. Citizens or permanent residents. This is a unique and novel program emphasizing the application of basic mechanisms to cancer treatment strategies, including ionizing radiation and hyperthermia. If you have any existing or potential trainees, please notify Dr. Dennis Leeper at (215)955-8092 or dennis.leeper@mail.tju.edu; or Dr. George Iliakis at (215)955-6473 or george.iliakis@mail.tju.edu). In addition there are two post-doctoral positions available funded by mechanisms that do not require U.S. permanent residency. These positions are in support of projects investigating (1) mechanisms of acute acidification and oxygenation of human tumor xenografts related to hyperthermia, radiation and/or chemotherapy sensitization; and (2) mechanisms of inhibition of tumor angiogenesis and the effect of angiogenesis inhibition on human tumor xenograft response to radiotherapy. Applicants must have training in some aspect of oncology research, preferably radiation research, and experience working with animals. Interested individuals should respond either to Dr. Dennis Leeper (dennis.leeper@mail.tju.edu) or Dr. Adam Dicker (adam.dicker@mail.tju.edu). Please attach a C.V.

Post –Doctoral Fellowship in Prognostic Radiology; University of Texas Southwestern Medical Center at Dallas: Immediate opening to join active “Prognostic Radiology” research team at UT-Southwestern. In the light of recent funding success, applicants aree welcome to develop nuclear magnetic resonance investigations of tumor physiology, with particular emphasis on pH, pO2 and blood flow in the prostate. Prior experience in molecular biology or organic synthetic chemistry an advantage. For further information contact Ralph P. Mason, Ph.D., C. Chem.; Associate Professor, Advanced Radiological Sciences; Department of Radiology, E6.238CA; The University of Texas Southwestern Medical Center at Dallas; 5323 Harry Hines Boulevard; Dallas, Texas 75390-9058. Phone: (214)648-8926; Fax: (214)648-2991; e-mail: Ralph.Mason@UTSouthwestern.edu. Web info: http://swnt240.swmed.edu/radiologicalsc/

Post-Doctoral Positions, NIH.  Three Postdoctoral Positions are available with the Nuclear Medicine Department, National Institutes of Health, Bethesda, MD to study the molecular and cellular effects of ionizing radiation. Current research interests include DNA repair mechanisms, particularly DNA double-strand break repair, structural analysis of radiation induced DNA damage, and methods for production of positioned radiation damage in nucleic acids. Candidates should possess a recent Ph.D., M.D., or equivalent degree (5 or fewer years postgraduate). Experience in molecular biology, biochemistry, or nucleic acid chemistry is a plus. Please send a CV with the names and contact information for 3 references, along with a brief description of your research experience to: Dr. Thomas A. Winters, Bldg. 10, Room 1C401, 10 Center Drive, Bethesda, MD, 20892-1180, e-mail: twinters@mail.nih.gov; Fax: (301)480-9712.

Research Associates, Armed Forces Radiobiology Research Institute. Regular and senior research associateship opportunities are available in a number of research areas.  Information is available from the AFRRI webiste (http://www.afrri.usuhs.mil). The Laboratory Program Representative is Dr. William F. Blakely, Applied Cellular Radiobiology Department, Armed Forces Radiobiology Research Institute, Bldg 42, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603. Telephone: (301)295-0484; e-mail: blakely@afrri.usuhs.mil

Postdoctoral, research associate and research assistant positions, King Faisal Specialist Hospital & Research Centre. The Radiation Biology Laboratory at the King Faisal Specialist Hospital & Research Centre (KFSH&RC) invites applications for positions at postdoctoral, research associate, and technician levels. Experience in cellular and/or molecular biology is required. Applicants for postdoctoral and research associate positions should have a PhD, MD or equivalent degree. Applicants for research assistant positions should have a bachelor in science or any other qualifying degree. Applicants with experience in cytogenetics are also encouraged to apply. Successful candidates will work as part of a research team studying radiosensitivity, cell cycle, DNA damage and repair, proteins and genes expression in cells derived from radiotherapy patients. Other projects such as cell aging and the effects of electromagnetic fields on human health are under development. KFSH&RC offers competitive tax-free salary with free accommodation and health coverage in addition to many other benefits such as relocation allowance, paid annual leave, 50 days vacations/year etc. To apply, please send your curriculum vitae to: Dr. Ghazi Alsbeih, Biomedical Physics Dept., KFSH&RC P.O. Box 3354, MBC-03, Riyadh 11211, Kingdom of Saudi Arabia. Telephone: (966-1)442-7891; Fax: (966-1)442-4777; e-mail: galsbeih@kfshrc.edu.sa. Applications will be accepted until the positions are filled. More information is available upon request.

Postdoctoral Research Scientist; Columbia University College of Physicians and Surgeons. Individual needed to study molecular mechanisms of radioresistance and radiation-induced changes in cell cycle progression, using mammalian cells and/or knockout mice. Candidate must have a Ph.D. in Molecular Biology, Biochemistry, Genetics or a related field, and have experience with recombinant DNA technology and tissue culture. A CV, along with the names and contact information for three individuals to serve as references should be sent to: Howard B. Lieberman, Center for Radiological Research, Columbia University, 630 W. 168th St., New York, NY 10032; or sent via e-mail to lieberman@cancercenter.columbia.edu. Columbia University is an Equal Opportunity/Affirmative Action employer.

Post-doctoral positions, New Jersey Medical School. Three post-doctoral positions are available immediately in the Division of Radiation Research to study 1) the mechanisms underlying the intercellular transmission of radiation damage signals, 2) The role of endogenous oxidative metabolism in the cellular responses to low dose/low dose rate ionizing radiation, 3) Effects of non-uniform distributions of radioactivity. A variety of human and rodent cells grown in two or three-dimensions and diverse molecular techniques are currently used for these studies. Alpha-particle irradiators as well as high and very low dose rate gamma irradiators with the capability of irradiating cells at various partial oxygen tensions are housed in our laboratory. The laboratory is adjacent to the University Core Molecular Biology, Confocal Microscopy and Flow Cytometry facilities. Modern computing facilities are available for theoretical modeling. These positions are suitable for candidates with Ph.D. and/or M.D. degrees and training in molecular biology techniques, tissue culture and cytogenetics analyses. Knowledge of cell signal transduction is highly desirable. To apply, please send curriculum vitae and the names and addresses of three References to Edouard Azzam, Ph.D, or Roger W. Howell, Ph.D., Department of Radiology (MSB – F451), New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA. e-mail: azzamei@umdnj.edu, rhowell@umdnj.edu; Fax: (973) 972 6474; Telephone: (973) 972 5067 or 972 5323.