Representative Publications: Liskin Swint-Kruse, Ph.D.

Swint-Kruse, L. and Brown, C. S.,  Resmap: Automated representation of macromolecular interfaces as two-dimensional network.  Bioinformatics, in press, available online..
online abstract:
http://bioinformatics.oxfordjournals.org/cgi/content/abstract/bti511?ijkey=bUXde5mKrrCdQgM&keytype=ref
online article:
http://bioinformatics.oxfordjournals.org/cgi/reprint/bti511?ijkey=bUXde5mKrrCdQgM&keytype=ref

Swint-Kruse, L.*, Zhan, H. L.*, and Matthews, K. S.  Hydrophobic mutations at LacI position 84 terminate the allosteric pathway before its completion.  In preparation.
*LSK and HLZ made equal contributions to this work 

Swint-Kruse, L., Zhan, H. L., and Matthews, K. S.  A new thermodynamic mechanism for the LacI functional cycle.  In preparation. 

Zhan, H. L., Swint-Kruse, L., and Matthews, K. S.  Effects of core pivot mutations on LacI allosteric properties.  In preparation. 

Swint-Kruse, L.  (2004)  Using networks to identify fine structural detail between functionally distinct protein states.  Biochemistry 43, 10886-10895. 

Swint-Kruse, L., Zhan, H. L., Fairbanks, B. M., Maheshawri, A., & Matthews, K. S.  (2003)  Perturbation from a distance:  Mutations that alter LacI function through long-range effects.  Biochemistry 42, 14004-14016.

Flynn*, T. C., Swint-Kruse*, L., Kong, Y., Booth, C., Matthews, K. S., & Ma, J. (2003)  Allosteric Transition Pathways in the Lactose Repressor Protein Core Domains.  Protein Science, 12, 2523-2541.
*TCF and LSK made equal contributions to this work.

Swint-Kruse, L., Larson, C., Pettitt, B. M., & Matthews K. S.  (2002)  Fine-tuning function:  Correlation of hinge domain interactions with functional distinctions between LacI and PurR.  Protein Science 11, 778-794.  A figure from this manuscript was used as the cover illustration.

Swint-Kruse, L., Elam, C. R., Lin, J., Wycuff, D. R. & Matthews, K. S.  (2001) Plasticity of quaternary structure:  Twenty-two ways to form LacI dimer. Protein Science 10, 262-276.

Swint-Kruse, L., Matthews, K. S., Smith, P. E., & Pettitt, B. M.  (1998)  Comparison of simulated and experimentally determined dynamics for a variant of the LacI DNA-binding domain, Nlac-P. Biophys. J. 74, 413-421.

Falcon, C. M., Swint-Kruse, L., & Matthews, K. S.  (1997)  Designed disulfide between N-terminal domains of Lactose Repressor disrupts allosteric linkage. J. Biol. Chem. 272, 26818-26821.

 Swint-Kruse, L. & Robertson, A. D.  (1996)  Temperature and pH dependences of hydrogen exchange and global stability for ovomucoid third domain. Biochemistry 35, 171-180 .

Swint-Kruse, L. & Robertson, A. D.  (1995)  Hydrogen bonds and the pH dependence of ovomucoid third domain stability.  Biochemistry 34, 4724-4732.

Swint, L. & Robertson, A. D.  (1993)  Thermodynamics of unfolding for turkey ovomucoid third domain:  Thermal and chemical denaturation.  Protein Science 2, 2037-2049.


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