Representative Publications: Owen Nadeau

 Nadeau, O.W. and Carlson, G.M., “Chemical Crosslinking in Studying Protein-protein Interactions,” in Protein-Protein Interactions, Chap. 6, Cold Spring Harbor Laboratory Press, New York, pp 75-91, 2002. 

Nadeau O. W., Carlson, G.M. and Gogol, E.P., “A Ca²⁺-Dependent Global Conformational Change in the 3D Structure of Phosphorylase Kinase Obtained from Electron Microscopy,” Structure 10:23-32, 2002. 

 Rice, N.A., Nadeau, O.W., Yang, Q. and Carlson, G. M., “The Calmodulin-binding Domain of the Catalytic g Subunit of Phosphorylase Kinase Interacts with Its Inhibitory a Subunit,” J. Biol. Chem. 277:14681-14687, 2002. 

Nadeau, O.W., Carlson, G.M. and Gogol, E.P., “Structural Evidence for a Global Ca²⁺-dependent Conformational Change in Phosphorylase Kinase,” Protein Science 10:449, 2001

 Nadeau, O.W., Domanski, P., Usacheva, A., Uddin, S., Platanias, L.C., Pitha, P., Raz, R., Levy, D., Majchrzak, B., Fish, E. and Colamonici, O.R., “The Proximal Tyrosines of the Cytoplasmic Domain of the β Chain of the Type I Interferon Receptor are Essential for Signal Transducer and Activator of Transcription (Stat) 2 Activation,” J. Biol. Chem. 274:4045-4052, 1999.

 Nadeau, O.W., Traxler, K.W., Fee, L.R., Baldwin, B.B. and Carlson, G.M., “Activators of Phosphorylase Kinase Alter the Cross-linking of its Catalytic Subunit to the C-terminal 1/6^th of its Regulatory α Subunit,” Biochemistry 38:2551-2559, 1999.

      Carlson, G.M. and Nadeau, O.W., “Bifunctional Crosslinking Reagents,” in The Encyclopedia of Molecular Biology, Ed. T.E. Creighton, Wiley, New York, pp 279-281, 1999.

Carlson, G.M. and Nadeau, O.W., “Crosslinking,” in The Encyclopedia of Molecular Biology, Ed. T.E. Creighton, Wiley, New York, pp 582-584, 1999.

Carlson, G.M. and Nadeau, O.W., “Enzyme Immobilization and Conjugation,” in The Encyclopedia of Molecular Biology, Ed. T.E. Creighton, Wiley, New York, pp 829, 1999.

 Carlson, G.M. and Nadeau, O.W., “Gluteraldehyde,” in The Encyclopedia of Molecular Biology, Ed. T.E. Creighton, Wiley, New York, pp 1019-1020, 1999.

Domanski, P., Nadeau, O.W., Platanias, L.C., Fish, E., Kellum, M., Pitha, P. and Colamonici, O.R., “Differential Use of the β_L Subunit of the Type I Interferon Receptor Determines Signaling Specificity for IFNα2 and IFNβ,” J. Biol. Chem. 273:3144-3147, 1998.

Platanias, L.C., Domanski, P., Nadeau, O.W., Yi, T., Uddin, S., Fish, E., Neel, B.G. and Colamonici, O.R., “Identification of a Domain in the β Subunit of the Type I Interferon (IFN) Receptor that Exhibits a Negative Regulatory Effect in the Growth Inhibitory Action of Type I IFNs,” J. Biol. Chem. 273:5577-5581, 1998.

Ayers, N.A., Nadeau, O.W., Read, M.W., Ray, P. and Carlson, G.M., “Effector-sensitive Cross-linking of Phosphorylase-b Kinase by the Novel Cross-linker 4-phenyl-1,2,4-triazoline-3,5-dione,” Biochem. J. 331:137-141, 1998.

 Nadeau, O.W., Traxler, K.W. and Carlson, G.M., “Zero-length Cross-linking of the β Subunit of Phosphorylase Kinase to the N-terminal Half of its Regulatory α Subunit,” Biochem. Biophys. Res. Commun. 251:637-641, 1998.

Nadeau, O.W., Sacks, D.B. and Carlson, G.M., “Differential Affinity Cross-Linking of Phosphorylase Kinase Conformers by the Geometric Isomers of Phenylenedimaleimide,” J. Biol. Chem. 272:26196-26201, 1997.

Nadeau, O.W., Sacks, D.B. and Carlson, G.M., “The Structural Effects of Endogenous and Exogenous Ca²⁺/Calmodulin on Phosphorylase Kinase,” J. Biol. Chem. 272:26202-26209, 1997. 

Domanski, P., Fish, E., Nadeau, O.W., Witte, M., Platanias, L.C., Yan, H., Krolewski, J., Pitha, P. and Colamonici, O.R., “A Region of the β Subunit of the Interferon a Receptor Different from Box 1 Interacts With Jak1 and Is Sufficient To Activate the Jak-Stat Pathway and Induce an Antiviral State,” J. Biol. Chem. 272:26388-26393, 1997.

Nadeau, O.W., Traxler, K.W. and Carlson, G.M., “The b Subunit of Phosphorylase Kinase Interacts with the N-terminal Domain of its Regulatory a Subunit,” Protein Science 6:146, 1997.

Ayers, N.A., Nadeau, O.W., Read, M.W., Ray, P. and Carlson, G.M., “Chemical Cross-linking of Phosphorylase-b Kinase by the Novel Cross-linker 4-phenyl-1,2,4-triazoline-3,5-dione,” FASEB Journal 11:A1180, 1997. 

Nadeau, O.W. and Carlson, G.M., “Ca²⁺ and Calmodulin Alter Interactions Between the Catalytic Subunit of Phosphorylase Kinase and the C-terminal Domain of its Regulatory α-subunit,” FASEB Journal 10:A1268, 1996.

Nadeau, O.W., Falick, A. and Woodworth, R.C., Structural Evidence For An Anion-Directing Track in the Hen Ovotransferrin N-Lobe: Implications for Transferrin Synergistic Anion-Binding,” Biochemistry 35:14294-14303, 1996.

Nadeau, O.W. and Carlson, G.M., “Zero-length Conformation-dependent Cross-linking of Phosphorylase Kinase Subunits by Transglutaminase,” J. Biol. Chem. 269:29670-29676, 1994.

Nadeau, O.W., Gump, D.W., Hendricks, G.M.  and Meyer, D.H., “Deposition of Bismuth by Yersinia enterocolitica,” Med. Microbiol. Immunol. 181:145-152, 1992.

Gump, D.W., Nadeau, O.W., Hendricks, G.M. and Meyer, D.H., “Evidence that Bismuth Salts Reduce Invasion of Epithelial Cells by Enteroinvasive Bacteria,” Med. Microbiol. Immunol. 181:131-143, 1992.

Hubbard, J.L., Morneau, A., Burns, R.M. and Nadeau, O.W., “Carbon-carbon Double Bond Formation from a cis-bis (chloromethyl) Complex,” J. Am. Chem. Soc. 113:9180-9184, 1991.