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Wilfred N. Arnold
Professor |
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I have had 25 years experience with yeast cell envelopes. Subject matter has included
both industrial and pathogenic yeasts, as well as the yeast-like organisms which cause
secondary infections in patients with compromised immune systems. The latter group of
microorganisms includes many dimorphic species which are of extreme importance in terms of
morbidity and mortality for HIV-infected patients. The long-term goal of my research is to
understand critical aspects of biochemistry, biophysics, and ultrastructure within these
pathogens (grown in pure culture) and to find chemical ways of selective interference - in
short, to propose better avenues of potential therapy for these infections. I also have a
secondary interest in History of Medicine, which has yielded popular publications in
Scientific American, British Medical Journal, Journal of the American Medical Association,
and a widely praised book on the underlying illness of Vincent van
Gogh.
Dr. Arnold's research has been adapted into two interactive medical teaching
units which may be found here.
An article on his research, and these teaching units, was featured in a recent KUMC
Highlight .