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Molecular & Integrative Physiology
Department of Molecular & Integrative Physiology  :  Faculty  :   Stanislav R. Svojanovsky, Ph.D., Ing.

Stanislav R. Svojanovsky, Ph.D., Ing.

Stanislav R. Svojanovsky, Ph.D., Ing. Ph.D. University of Kansas, 2000
Ing. University of Pardubice, Czech Republic, 1982

2025 Kansas Life Sciences Innovations Center
3901 Rainbow Boulevard
Kansas City, KS 66160-7401
Phone: (913) 588-7266
Fax: (913) 588-7430
ssvojanovsky@kumc.edu

Research Interest

The most fascinating characteristic of all living things is their ability to store, utilize, and pass on information. Bioinformatics utilizes multiple data-based computational analyses of diverse disciplines in biomedical research. It is primarily used to study the biology and genetics of many organisms from the less complex (multi-cellular organisms) to the most complicated organism, human. My research is focused on bioinformatics strives to resolve what information is biologically important and to decipher how it is used to properly control the environment within living organisms. Through the analyses of diverse biological databases, various computational models can be constructed to approximate many complex processes responsible for life-science systems and greatly increase our knowledge of comparative genetics, and how related genes encode functionally related proteins.

Representative publications

Chakrabarty A, Blacklock A, Svojanovsky SR, Smith PG. 2008. Estrogen elicits dorsal root ganglion axon sprouting via a renin-angiotensin system. Endocrinology. 149(7):3452-60.

Truog WE, Xu D, Ekekezie I, Mabry S, Rezaiekhaligh M, Svojanovsky SR, Soares MJ. 2008. Chronic hypoxia and rat lung development: Analysis by morphometry and directed microarray. Pediatr. Res. 64(1): 56-62.

Sun A, Tang J, Hong Y, Song J, Terranova PF, Thrasher JB, Svojanovsky SR, Wang HG, Li B. 2008. Androgen receptor-dependent regulation of Bcl-xL expression: Implication in prostate cancer progression. Prostate, 68(4): 453-61.

Puri V, Puri S, Svojanovsky SR, Mathur S, Macgregor RR, Klein RM, Welch KM, Berman NE. 2006. Effects of oestrogen on trigeminal ganglia in culture: implications for hormonal effects on migraine. Cephalalgia, 26(1): 33-42.

Naranatt PP, Krishnan HH, Svojanovsky SR, Bloomer C, Mathur S, Chandran B. 2005. Host gene induction and transcriptional reprogramming in Kaposi’s-sarcoma associated herpesvirus (KSHV/HHV-8)            infected endothelial, fibroblast and B cells: insights into modulation events early during infection. Cancer Research, 64(1): 72-84.

Werle MJ, Brownback K, VanSaun MN, Rodova M, Svojanovsky SR. Gene array of four day Denervated mouse gastrocnemius muscle. Society for Neuroscience Journal, November 2003. http://www.kumc.edu/werlelab/genearray/index.html

Rogan PK, Svojanovsky SR, Leeder JS. 2003. Information theory-based analysis of CYP2C19, CYP2C6 and CYP3A5 splicing mutations. Pharmacogenetics, 13(4): 207-21.

 

Bioinformatics at KUMC

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