Research Interests
Neuropharmacology, neurotoxicology, immunotoxicology
I am currently a Chancellor’s Teaching Professor and devote most of my time to teaching. My past research interests have focused on the effects of drugs and chemicals on brain function and structure using quantitative computer-assisted analysis to study local cerebral glucose utilization and employing a variety of approaches to understand the role of reactive oxygen species in causing brain damage. I am also interested understanding the role of "limbic sensitization" in relationship to CNS disorders. I currently spend most of my efforts in maintaining and developing the Departments computer-based education program to support the education of medical students and other health professionals.
Pazdernik, T.L., M.R. Emerson, R. Cross, S.R. Nelson and F.E. Samson. Soman-induced seizures: Limbic activity, Oxidative stress and Neuroprotective proteins. J. Appl. Toxicol. 21: S87- S94, 2001.
Richards, T.L., T.L. Pazdernik, and B. Levant. Clorgyline-induced modification of behavioral sensitization to quinpirole: Effects on local cerebral glucose utilization. Brain Res. 1160: 124-133 (2007)
Pazdernik, T. L. & L. Kerecsen, (authors) Rapid Review of Pharmacology, Mosby, Philadelphia; 2nd Ed.; (2007).
Richards, TL, TL Pazdernik, and B Levant. Basal local cerebral glucose use is not altered after behavioral sensitization to quinpirole. Neuroscience Letters. 429: 165-68 (2007).
Kerecsen, L. and T.L. Pazdernik. From Mainframe to Web-Based: 30 years of Experience in Computer Aided Instruction of Pharmacology. Nauyn-Schmiedeberg's Archives of Pharmacology 366: 83- 89 (2002).
Thomas L. Pazdernik, Ph.D.
Professor
Department of Pharmacology, Toxicology and Therapeutics
The University of Kansas Medical Center
4083 KSLIC, MS1018
3901 Rainbow Boulevard
Kansas City, KS 66103
Phone: (913) 588-7504/7140
Fax: (913) 588-7501
E-mail: tpazdern@kumc.edu
Curriculum Vitae in PDF Format
Updated 9/5/08
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The University of Kansas Medical Center