Research Interests
Neuropharmacology, neurotoxicology, immunotoxicology
My research interests have focused on the effects of drugs and chemicals on brain function and structure using quantitative computer-assisted analysis to study local cerebral glucose utilization and employing a variety of approaches to understand the role of reactive oxygen species in causing brain damage. I am also interested understanding the role of "limbic sensitization" in relationship to CNS disorders. I currently spend most of my efforts in maintaining and developing the Departments computer-based education program to support the education of medical students and other health professionals.
Emerson, M.R., F.E. Samson and T.L. Pazdernik. Effects of Hypoxia Preconditionig on Expression of Metallothioein-1,2 and Hemeoxygenase-1 before and after kainic acid-induced seizures. Cellular and Molecular Biology. 46:619- 626, 2000.
Nelson, S.R., T. L. Pazdernik and F.E. Samson. Measurement of Loosely-Bound Iron in Brain Regions using Redox Cycling and Salicylate. Cellular and Molecular Biology. 46:649-655, 2000.
Pazdernik, T.L., M.R. Emerson, R. Cross, S.R. Nelson and F.E. Samson. Soman-induced seizures: Limbic activity, Oxidative stress and Neuroprotective proteins. J. Appl. Toxicol. 21: S87- S94, 2001.
Kerecsen, L. and T.L. Pazdernik. From Mainframe to Web-Based: 30 years of Experience in Computer Aided Instruction of Pharmacology. Nauyn-Schmiedeberg's Archives of Pharmacology 366: 83- 89 (2002).
Pazdernik, T.L., L Kerecsen and M.K. Shaw. "Pharmacology, Rapid Review", Mosby, St. Louis (2003).
Thomas L. Pazdernik, Ph.D.
Professor
Department of Pharmacology, Toxicology and Therapeutics
The University of Kansas Medical Center
4083 KSLIC, MS1018
3901 Rainbow Boulevard
Kansas City, KS 66103
Phone: (913) 588-7504/7140
Fax: (913) 588-7501
E-mail: tpazdern@kumc.edu
Curriculum Vitae in PDF Format
Updated 2/1/07
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The University of Kansas Medical Center