Stephanie Bishop

 

B.A.. in Biology, University of Kansas

M.A. in Biochemistry and Biophysics, University of Kansas

 

A Lawrence, Kansas native, I earned a B.A. in Biology in 2001 and after spending several years working in the biotech industry, an M.A. in Biochemistry and Biophysics from the University of Kansas in 2009.  I am pursuing a degree in Pharmacology at the KU Medical Center. In my spare time, I enjoy cycling, running with my lazy Great Dane, and gardening.

Research Interests

Under the supervision of Bao Ting Zhu, Ph.D., my research focuses on trying to understand cholesterol metabolism in neurons, with a specific focus on elucidating proliferative effects of cholesterol derivatives on neural cells in vitro.  Because cholesterol has become increasingly acknowledged as imperative to learning and memory formation, a clear understanding of cholesterol metabolism has become increasingly pertinent to elucidating the manifestation and physiology of Alzheimer’s disease.  Because the blood brain barrier prevents exchange of cholesterol with the peripheral circulating supply, the sole cholesterol metabolizing enzyme in the brain, Cyp46A1, has recently been identified as playing a crucial role in regulating brain cholesterol levels.  Understanding the role of this enzyme in cholesterol metabolism and elucidating mechanisms of cell proliferation with the ultimate goal of developing Alzheimer’s therapy are two fledgling goals of my research.

As a Kansas University Madison and Lila Self Graduate Fellow, not only are my stipend and tuition expenses covered, but I also participate in a development program that provides additional training in leadership, communication, and management. Information about the Self Fellowship can be found at http://www2.ku.edu/~selfpro/.

Publications

Stephanie C. Bishop, Long primer extension by a novel inverse PCR method, Master’s Thesis, Kansas University, 2009.

Stephanie C. Bishop, Kim K. Colvert, Nicholas C. Barnthouse, Andrew P. Pirotte, Gale Haslam, Hardeep S. Samra, Paul A. Kitos and Mark L. Richter, Sensitive Measurement of Intracellular ATP Concentrations, in preparation.

Stephanie C. Bishop, Joseph A. Burlison, and Brian S. J. Blagg, Hsp90: a Novel Target for the Disruption of Multiple Signaling Cascades, Current Cancer Drug Targets, Vol. 7, No. 4, 2007, 369 – 388.

Ellen E. Quillen, Gale C. Haslam, Hardeep S. Samra, Darius Amani-Taleshi, Jeffrey A. Knight, Diane E. Wyatt, Stephanie C. Bishop, Kim K. Colvert, Mark L. Richter, and Paul A. Kitos, Ecto-adenylate kinase and plasma membrane ATP synthase activities of human vascular endothelial cells, Journal of Biological Chemistry, Vol. 281, No. 30, 2006, 20728 - 20737.

Contact Information

Stephanie C. Bishop
Madison and Lila Self Graduate Fellow

Department of Pharmacology, Toxicology, and Therapeutics
The University of Kansas Medical Center
MS1018, 4036 KLSIC
3901 Rainbow Blvd,
Kansas City, KS 66160
Phone: (913) 588-9180
Fax: (913) 588-7501
E-Mail: sbishop@kumc.edu

Updated 7/23/09