TRAUMATIC INJURIES, SPINAL CORD/BRAIN

HUMAN STUDIES

Autologous bone marrow mesenchymal stem cell therapy in the subacute stage of traumatic brain injury by lumbar puncture.
Tian C, Wang X, Wang X, Wang L, Wang X, Wu S, Wan Z.
ExpClin Transplant. 2013 Apr;11(2):176-81. doi: 10.6002/ect.2012.0053. Epub 2012 Aug 11.
FREE ARTICLE

A clinical trial report of autologous bone marrow-derived mesenchymal stem cell transplantation in patients with spinal cord injury.
Jiang PC, Xiong WP, Wang G, Ma C, Yao WQ, Kendell SF, Mehling BM, Yuan XH, Wu DC.
Exp Ther Med. 2013 Jul;6(1):140-146. Epub 2013 Apr 29.
FREE ARTICLE

Autologous olfactory ensheathing cell transplantation in human paraplegia: a 3-year clinical trial.
Mackay-Sim A, Féron F, Cochrane J, Bassingthwaighte L, Bayliss C, Davies W, Fronek P, Gray C, Kerr G, Licina P, Nowitzke A, Perry C, Silburn PA, Urquhart S, Geraghty T.
Brain. 2008 Sep;131(Pt 9):2376-86. doi: 10.1093/brain/awn173. Epub 2008 Aug 8.
FREE ARTICLE

Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte macrophage-colony stimulating factor: Phase I/II clinical trial.
Yoon SH, Shim YS, Park YH, Chung JK, Nam JH, Kim MO, Park HC, Park SR, Min BH, Kim EY, Choi BH, Park H, Ha Y.
Stem Cells. 2007 Aug;25(8):2066-73. Epub 2007 Apr 26.
FREE ARTICLE

Olfactory mucosa autografts in human spinal cord injury: a pilot clinical study.
Lima C, Pratas-Vital J, Escada P, Hasse-Ferreira A, Capucho C, Peduzzi JD.
J Spinal Cord Med. 2006;29(3):191-203; discussion 204-6.
FREE ARTICLE

 

PRECLINICAL STUDIES

Combination of temperature-sensitive stem cells and mild hypothermia: a new potential therapy for severe traumatic brain injury.
Tu Y, Chen C, Sun HT, Cheng SX, Liu XZ, Qu Y, Li XH, Zhang S.
J Neurotrauma. 2012 Sep 20;29(14):2393-403. doi: 10.1089/neu.2012.2374. Epub 2012 Jul 13.
FREE ARTICLE

Significant clinical, neuropathological and behavioural recovery from acute spinal cord trauma by transplantation of a well-defined somatic stem cell from human umbilical cord blood.
Schira J, Gasis M, Estrada V, Hendricks M, Schmitz C, Trapp T, Kruse F, Kögler G, Wernet P, Hartung HP, Müller HW.
Brain. 2012 Feb;135(Pt 2):431-46. doi: 10.1093/brain/awr222. Epub 2011 Sep 8.
FREE ARTICLE

Human mesenchymal stem cells modulate inflammatory cytokines after spinal cord injury in rat.
Urdzíková LM, Růžička J, LaBagnara M, Kárová K, Kubinová Š, Jiráková K, Murali R, Syková E, Jhanwar-Uniyal M, Jendelová P.
Int J Mol Sci. 2014 Jun 25;15(7):11275-93. doi: 10.3390/ijms150711275.
FREE ARTICLE

Combination therapy of human umbilical cord blood cells and granulocyte colony stimulating factor reduces histopathological and motor impairments in an experimental model of chronic traumatic brain injury.
Acosta SA, Tajiri N, Shinozuka K, Ishikawa H, Sanberg PR, Sanchez-Ramos J, Song S, Kaneko Y, Borlongan CV.
PLoS One. 2014 Mar 12;9(3):e90953. doi: 10.1371/journal.pone.0090953. eCollection 2014.
FREE ARTICLE

Human umbilical cord blood-derived mesenchymal stem cell transplantation for the treatment of spinal cord injury.
Cui B, Li E, Yang B, Wang B.
Exp Ther Med. 2014 May;7(5):1233-1236. Epub 2014 Mar 6.
FREE ARTICLE

Oral mucosa stem cells alleviates spinal cord injury-induced neurogenic bladder symptoms in rats.
Cho YS, Ko IG, Kim SE, Lee SM, Shin MS, Kim CJ, Kim SH, Jin JJ, Kim KH.
J Biomed Sci. 2014 May 13;21:43. doi: 10.1186/1423-0127-21-43.
FREE ARTICLE

Transplantation of bone marrow mesenchymal stem cells pretreated with valproic acid in rats with an acute spinal cord injury.
Chen L, Cui X, Wu Z, Jia L, Yu Y, Zhou Q, Hu X, Xu W, Luo D, Liu J, Xiao J, Yan Q, Cheng L.
Biosci Trends. 2014 Apr;8(2):111-9.
FREE ARTICLE

Use of autologous mesenchymal stem cells derived from bone marrow for the treatment of naturally injured spinal cord in dogs.
Penha EM, Meira CS, Guimarães ET, Mendonça MV, Gravely FA, Pinheiro CM, Pinheiro TM, Barrouin-Melo SM, Ribeiro-Dos-Santos R, Soares MB.
Stem Cells Int. 2014;2014:437521. doi: 10.1155/2014/437521. Epub 2014 Feb 25.
FREE ARTICLE

Intrathecal injection of human umbilical cord blood stem cells attenuates spinal cord ischaemic compromise in rats.
Judas GI, Ferreira SG, Simas R, Sannomiya P, Benício A, da Silva LF, Moreira LF.
Interact Cardiovasc Thorac Surg. 2014 Jun;18(6):757-62. doi: 10.1093/icvts/ivu021. Epub 2014 Mar 4.
FREE ARTICLE

Transplantation of adult monkey neural stem cells into a contusion spinal cord injury model in rhesus macaque monkeys.
Nemati SN, Jabbari R, Hajinasrollah M, Zare Mehrjerdi N, Azizi H, Hemmesi K, Moghiminasr R, Azhdari Z, Talebi A, Mohitmafi S, Vosough Taqi Dizaj A, Sharifi G, Baharvand H, Rezaee O, Kiani S.
Cell J. 2014 Summer;16(2):117-30. Epub 2014 May 25.
FREE ARTICLE

Therapeutic effect of transplanting bone mesenchymal stem cells on the hind limbs' motor function of rats with acute spinal cord injury.
Song Q, Xu R, Zhang Q, Ma M, Zhao X.
Int J Clin Exp Med. 2014 Jan 15;7(1):262-7. eCollection 2014.
FREE ARTICLE

Genetic modification of mesenchymal stem cells in spinal cord injury repair strategies.
Cui X, Chen L, Ren Y, Ji Y, Liu W, Liu J, Yan Q, Cheng L, Sun YE.
Biosci Trends. 2013 Oct;7(5):202-8.
FREE ARTICLE

Transplantation of schwann cells differentiated from adipose stem cells improves functional recovery in rat spinal cord injury.
Zaminy A, Shokrgozar MA, Sadeghi Y, Norouzian M, Heidari MH, Piryaei A.
Arch Iran Med. 2013 Sep;16(9):533-41. doi: 013169/AIM.0011.
FREE ARTICLE

Transplanting p75-suppressed bone marrow stromal cells promotes functional behavior in a rat model of spinal cord injury.
Edalat H, Hajebrahimi Z, Pirhajati V, Movahedin M, Tavallaei M, Soroush MR, Mowla SJ.
Iran Biomed J. 2013;17(3):140-5.
FREE ARTICLE

Clinical neurofunctional rehabilitation of a cat with spinal cord injury after hemilaminectomy and autologous stem cell transplantation.
Penha EM, Aguiar PH, Barrouin-Melo SM, de Lima RS, da Silveira AC, Otelo AR, Pinheiro CM, Ribeiro-Dos-Santos R, Soares MB.
Int J Stem Cells. 2012 Nov;5(2):146-50.
FREE ARTICLE

Comparison of mesenchymal stem cells derived from fat, bone marrow, Wharton's jelly, and umbilical cord blood for treating spinal cord injuries in dogs.
Ryu HH, Kang BJ, Park SS, Kim Y, Sung GJ, Woo HM, Kim WH, Kweon OK.
J Vet Med Sci. 2012 Dec;74(12):1617-30. Epub 2012 Aug 9.
FREE ARTICLE

Mesenchymal stem cell graft improves recovery after spinal cord injury in adult rats through neurotrophic and pro-angiogenic actions.
Quertainmont R, Cantinieaux D, Botman O, Sid S, Schoenen J, Franzen R.
PLoS One. 2012;7(6):e39500. doi: 10.1371/journal.pone.0039500. Epub 2012 Jun 20.
FREE ARTICLE

Fate of transplanted bone marrow derived mesenchymal stem cells following spinal cord injury in rats by transplantation routes.
Kang ES, Ha KY, Kim YH.
J Korean Med Sci. 2012 Jun;27(6):586-93. doi: 10.3346/jkms.2012.27.6.586. Epub 2012 May 26.
FREE ARTICLE

Reduction of lesion in injured rat spinal cord and partial functional recovery of motility after bone marrow derived mesenchymal stem cell transplantation.
Karaoz E, Kabatas S, Duruksu G, Okcu A, Subasi C, Ay B, Musluman M, Civelek E.
Turk Neurosurg. 2012;22(2):207-17. doi: 10.5137/1019-5149.JTN.5412-11.1.
FREE ARTICLE

Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice.
Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, Fujiyoshi K, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Yamanaka S, Nakamura M, Okano H.
Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16825-30. doi: 10.1073/pnas.1108077108. Epub 2011 Sep 26.
FREE ARTICLE

Functional recovery and neural differentiation after transplantation of allogenic adipose-derived stem cells in a canine model of acute spinal cord injury.
Ryu HH, Lim JH, Byeon YE, Park JR, Seo MS, Lee YW, Kim WH, Kang KS, Kweon OK.
J Vet Sci. 2009 Dec;10(4):273-84.
FREE ARTICLE

Transplantation of human umbilical mesenchymal stem cells from Wharton's jelly after complete transection of the rat spinal cord.
Yang CC, Shih YH, Ko MH, Hsu SY, Cheng H, Fu YS.
PLoS One. 2008;3(10):e3336. doi: 10.1371/journal.pone.0003336. Epub 2008 Oct 6.
FREE ARTICLE

Transplanted neural progenitor cells survive and differentiate but achieve limited functional recovery in the lesioned adult rat spinal cord.
Webber DJ, Bradbury EJ, McMahon SB, Minger SL.
Regen Med. 2007 Nov;2(6):929-45.
FREE ARTICLE

In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury.
Okada S, Ishii K, Yamane J, Iwanami A, Ikegami T, Katoh H, Iwamoto Y, Nakamura M, Miyoshi H, Okano HJ, Contag CH, Toyama Y, Okano H.
FASEB J. 2005 Nov;19(13):1839-41. Epub 2005 Sep 1.
FREE ARTICLE

REVIEW ARTICLES

Concise review: the potential of stromal cell-derived factor 1 and its receptors to promote stem cell functions in spinal cord repair.
Jaerve A, Schira J, Müller HW.
Stem CellsTransl Med. 2012 Oct;1(10):732-9. doi: 10.5966/sctm.2012-0068. Epub 2012 Oct 10. Review.
FREE ARTICLE

Mesenchymal stem cells in the treatment of spinal cord injuries: A review.
Dasari VR, Veeravalli KK, Dinh DH.
World J Stem Cells. 2014 Apr 26;6(2):120-33. doi: 10.4252/wjsc.v6.i2.120. Review.
FREE ARTICLE

Progress of mesenchymal stem cell therapy for neural and retinal diseases.
Ng TK, Fortino VR, Pelaez D, Cheung HS.
World J Stem Cells. 2014 Apr 26;6(2):111-9. doi: 10.4252/wjsc.v6.i2.111. Review.
FREE ARTICLE

A meta-analysis of the motion function through the therapy of spinal cord injury with intravenous transplantation of bone marrow mesenchymal stem cells in rats.
Zhang D, He X.
PLoS One. 2014 Apr 1;9(4):e93487. doi: 10.1371/journal.pone.0093487. eCollection 2014.
FREE ARTICLE

Stem cell transplantation in traumatic spinal cord injury: a systematic review and meta-analysis of animal studies.
Antonic A, Sena ES, Lees JS, Wills TE, Skeers P, Batchelor PE, Macleod MR, Howells DW.
PLoS Biol. 2013 Dec;11(12):e1001738. doi: 10.1371/journal.pbio.1001738. Epub 2013 Dec 17. Review.
FREE ARTICLE

Stem cells for spinal cord regeneration: Current status.
Sobani ZA, Quadri SA, Enam SA.
Surg Neurol Int. 2010 Dec 25;1:93. doi: 10.4103/2152-7806.74240.
FREE ARTICLE

Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury.
Cao FJ, Feng SQ.
Chin Med J (Engl). 2009 Jan 20;122(2):225-31. Review.
FREE ARTICLE

Human nerual stem cells for brain repair.
Kim SU, Lee HJ, Park IH, Chu K, Lee ST, Kim M, Roh JK, Kim SK, Wang KC.
Int J Stem Cells. 2008 Nov;1(1):27-35. Review.
FREE ARTICLE

Last modified: Sep 11, 2014
ID=x22379