OSTEOPOROSIS

HUMAN STUDIES

Beneficial effects of non-matched allogeneic cord blood mononuclear cells upon patients with idiopathic osteoporosis.
Li J, Zhang L, Zhou L, Yu ZP, Qi F, Liu B, Zi SX, Li L, Li Y, Wang SB, Cui ZJ, Pan XH.
J Transl Med. 2012 May 21;10:102. doi: 10.1186/1479-5876-10-102.
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Effects of bisphosphonate treatment on circulating osteogenic endothelial progenitor cells in postmenopausal women.
Peris P, Atkinson EJ, Gössl M, Kane TL, McCready LK, Lerman A, Khosla S, McGregor UI.
Mayo Clin Proc. 2013 Jan;88(1):46-55. doi: 10.1016/j.mayocp.2012.08.019. Epub 2012 Dec 8.
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PRECLINICAL STUDIES

Transplantation of mesenchymal stem cells overexpressing RANK-Fc or CXCR4 prevents bone loss in ovariectomized mice.
Cho SW, Sun HJ, Yang JY, Jung JY, An JH, Cho HY, Choi HJ, Kim SW, Kim SY, Kim D, Shin CS.
Mol Ther. 2009 Nov;17(11):1979-87. doi: 10.1038/mt.2009.153. Epub 2009 Jul 14.
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Human umbilical cord blood-derived CD34+ cells reverse osteoporosis in NOD/SCID mice by altering osteoblastic and osteoclastic activities.
Aggarwal R, Lu J, Kanji S, Joseph M, Das M, Noble GJ, McMichael BK, Agarwal S, Hart RT, Sun Z, Lee BS, Rosol TJ, Jackson R, Mao HQ, Pompili VJ, Das H.
PLoS One. 2012;7(6):e39365. doi: 10.1371/journal.pone.0039365. Epub 2012 Jun 18.
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Transplantation of mesenchymal stem cells from young donors delays aging in mice.
Shen J, Tsai YT, Dimarco NM, Long MA, Sun X, Tang L.
Sci Rep. 2011;1:67. doi: 10.1038/srep00067. Epub 2011 Aug 18.
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Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary-induced obesity.
Luu YK, Capilla E, Rosen CJ, Gilsanz V, Pessin JE, Judex S, Rubin CT.
J Bone Miner Res. 2009 Jan;24(1):50-61. doi: 10.1359/jbmr.080817.
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Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents.
Yamaza T, Miura Y, Bi Y, Liu Y, Akiyama K, Sonoyama W, Patel V, Gutkind S, Young M, Gronthos S, Le A, Wang CY, Chen W, Shi S.
PLoS One. 2008 Jul 9;3(7):e2615. doi: 10.1371/journal.pone.0002615.
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Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice.
Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, Purton LE, Glimcher LH, Lian JB, Stein G, Anderson KC, Scadden DT.
J Clin Invest. 2008 Feb;118(2):491-504. doi: 10.1172/JCI33102.
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Treatment of senile osteoporosis in SAMP6 mice by intra-bone marrow injection of allogeneic bone marrow cells.
Takada K, Inaba M, Ichioka N, Ueda Y, Taira M, Baba S, Mizokami T, Wang X, Hisha H, Iida H, Ikehara S.
Stem Cells. 2006 Feb;24(2):399-405. Epub 2005 Aug 18.
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Prevention of senile osteoporosis in SAMP6 mice by intrabone marrow injection of allogeneic bone marrow cells.
Ichioka N, Inaba M, Kushida T, Esumi T, Takahara K, Inaba K, Ogawa R, Iida H, Ikehara S.
Stem Cells. 2002;20(6):542-51.
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REVIEW ARTICLES

Concise review: adipose-derived stromal cells for skeletal regenerative medicine.
Levi B, Longaker MT.
Stem Cells. 2011 Apr;29(4):576-82. doi: 10.1002/stem.612. Review.
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From stem cells to bone: phenotype acquisition, stabilization, and tissue engineering in animal models.
Gordeladze JO, Reseland JE, Duroux-Richard I, Apparailly F, Jorgensen C.
ILAR J. 2009;51(1):42-61. Review.
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Prospects for osteoprogenitor stem cells in fracture repair and osteoporosis.
Clines GA.
Curr Opin Organ Transplant. 2010 Feb;15(1):73-8. doi: 10.1097/MOT.0b013e328333d52c. Review.
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Adipose mesenchymal stem cells in the field of bone tissue engineering.
Romagnoli C, Brandi ML.
World J Stem Cells. 2014 Apr 26;6(2):144-52. doi: 10.4252/wjsc.v6.i2.144. Review.
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Mesenchymal Stem Cells in Bone Regeneration.
Knight MN, Hankenson KD.
Adv Wound Care (New Rochelle). 2013 Jul;2(6):306-316. Review.
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Last modified: Oct 14, 2014
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