OSTEONECROSIS (AVASCULAR NECROSIS)

HUMAN STUDIES

Use of concentrated bone marrow aspirate and platelet rich plasma during minimally invasive decompression of the femoral head in the treatment of osteonecrosis.
Martin JR, Houdek MT, Sierra RJ.
Croat Med J. 2013 Jun;54(3):219-24.
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Clinical results of auto-iliac cancellous bone grafts combined with implantation of autologous bone marrow cells for osteonecrosis of the femoral head: a minimum 5-year follow-up.
Kang JS, Moon KH, Kim BS, Kwon DG, Shin SH, Shin BK, Ryu DJ.
Yonsei Med J. 2013 Mar 1;54(2):510-5. doi: 10.3349/ymj.2013.54.2.510.
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Stem cell implantation for osteonecrosis of the femoral head.
Lim YW, Kim YS, Lee JW, Kwon SY.
ExpMol Med. 2013 Nov 15;45:e61. doi: 10.1038/emm.2013.128.
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The efficacy of targeted intraarterial delivery of concentrated autologous bone marrow containing mononuclear cells in the treatment of osteonecrosis of the femoral head: a five year follow-up study.
Mao Q, Jin H, Liao F, Xiao L, Chen D, Tong P.
Bone. 2013 Dec;57(2):509-16. doi: 10.1016/j.bone.2013.08.022. Epub 2013 Aug 29.
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Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series.
Pak J.
J Med Case Rep. 2011 Jul 7;5:296. doi: 10.1186/1752-1947-5-296.
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PRECLINICAL STUDIES

The effects of autologous bone marrow mesenchymal stem cell arterial perfusion on vascular repair and angiogenesis in osteonecrosis of the femoral head in dogs.
Jin H, Xia B, Yu N, He B, Shen Y, Xiao L, Tong P.
IntOrthop. 2012 Dec;36(12):2589-96. doi: 10.1007/s00264-012-1674-7. Epub 2012 Oct 13.
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HGF-transgenic MSCs can improve the effects of tissue self-repair in a rabbit model of traumatic osteonecrosis of the femoral head.
Wen Q, Jin D, Zhou CY, Zhou MQ, Luo W, Ma L.
PLoS One. 2012;7(5):e37503. doi: 10.1371/journal.pone.0037503. Epub 2012 May 21.
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Stem cell- and growth factor-based regenerative therapies for avascular necrosis of the femoral head.
Rackwitz L, Eden L, Reppenhagen S, Reichert JC, Jakob F, Walles H, Pullig O, Tuan RS, Rudert M, Nöth U.
Stem Cell Res Ther. 2012 Feb 22;3(1):7. doi: 10.1186/scrt98. Review.
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REVIEW ARTICLES

Stem cell therapy for the treatment of early stage avascular necrosis of the femoral head: a systematic review.
Lau RL, Perruccio AV, Evans HM, Mahomed SR, Mahomed NN, Gandhi R.
BMC MusculoskeletDisord. 2014 May 16;15(1):156. doi: 10.1186/1471-2474-15-156.
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Stem cell treatment for avascular necrosis of the femoral head: current perspectives.
Houdek MT, Wyles CC, Martin JR, Sierra RJ.
Stem Cells Cloning. 2014 Apr 9;7:65-70. eCollection 2014. Review.
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Last modified: Jul 17, 2014
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