CONNECTIVE TISSUE DISEASES

HUMAN STUDIES

Local implantation of autologous mononuclear cells from bone marrow and peripheral blood for treatment of ischaemic digits in patients with connective tissue diseases.
Kamata Y, Takahashi Y, Iwamoto M, Matsui K, Murakami Y, Muroi K, Ikeda U, Shimada K, Yoshio T, Okazaki H, Minota S.
Rheumatology (Oxford). 2007 May;46(5):882-4. Epub 2007 Feb 19.
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Autologous haematopoietic stem cell transplants for autoimmune disease--feasibility and transplant-related mortality. Autoimmune Disease and Lymphoma Working Parties of the European Group for Blood and Marrow Transplantation, the European League Against Rheumatism and the International Stem Cell Project for Autoimmune Disease.
Tyndall A, Fassas A, Passweg J, Ruiz de Elvira C, Attal M, Brooks P, Black C, Durez P, Finke J, Forman S, Fouillard L, Furst D, Holmes J, Joske D, Jouet J, Kötter I, Locatelli F, Prentice H, Marmont AM, McSweeney P, Musso M, Peter HH, Snowden JA, Sullivan K, Gratwohl A, et al.
Bone Marrow Transplant. 1999 Oct;24(7):729-34.
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Autologous stem-cell transplantation in refractory autoimmune diseases after in vivo immunoablation and ex vivo depletion of mononuclear cells.
Rosen O, Thiel A, Massenkeil G, Hiepe F, Häupl T, Radtke H, Burmester GR, Gromnica-Ihle E, Radbruch A, Arnold R.
Arthritis Res. 2000;2(4):327-36. Epub 2000 Jun 8.
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Stem cell treatment for patients with autoimmune disease by systemic infusion of culture-expanded autologous adipose tissue derived mesenchymal stem cells.
Ra JC, Kang SK, Shin IS, Park HG, Joo SA, Kim JG, Kang BC, Lee YS, Nakama K, Piao M, Sohl B, Kurtz A.
J Transl Med. 2011 Oct 21;9:181. doi: 10.1186/1479-5876-9-181.
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Prolonged remission state of refractory adult onset Still's disease following CD34-selected autologous peripheral blood stem cell transplantation.
Lanza F, Dominici M, Govoni M, Moretti S, Campioni D, Corte RL, Latorraca A, Tieghi A, Castagnari B, Trotta F, Castoldi G.
Bone Marrow Transplant. 2000 Jun;25(12):1307-10.
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A phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease.
Tsukamoto H, Nagafuji K, Horiuchi T, Miyamoto T, Aoki K, Takase K, Henzan H, Himeji D, Koyama T, Miyake K, Inoue Y, Nakashima H, Otsuka T, Tanaka Y, Nagasawa K, Harada M.
Ann Rheum Dis. 2006 Apr;65(4):508-14. Epub 2005 Aug 26.
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PRECLINICAL STUDIES

Mesenchymal stromal cells improve salivary function and reduce lymphocytic infiltrates in mice with Sjögren's-like disease.
Khalili S, Liu Y, Kornete M, Roescher N, Kodama S, Peterson A, Piccirillo CA, Tran SD.
PLoS One. 2012;7(6):e38615. doi: 10.1371/journal.pone.0038615. Epub 2012 Jun 7.
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Kallikrein transduced mesenchymal stem cells protect against anti-GBM disease and lupus nephritis by ameliorating inflammation and oxidative stress.
Li Y, Raman I, Du Y, Yan M, Min S, Yang J, Fang X, Li W, Lu J, Zhou XJ, Mohan C, Li QZ.
PLoS One. 2013 Jul 23;8(7):e67790. doi: 10.1371/journal.pone.0067790. Print 2013.
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Intratunical injection of human adipose tissue-derived stem cells prevents fibrosis and is associated with improved erectile function in a rat model of Peyronie's disease.
Castiglione F, Hedlund P, Van der Aa F, Bivalacqua TJ, Rigatti P, Van Poppel H, Montorsi F, De Ridder D, Albersen M.
Eur Urol. 2013 Mar;63(3):551-60. doi: 10.1016/j.eururo.2012.09.034. Epub 2012 Sep 24. Erratum in: Eur Urol. 2013 Jul;64(1):e21.
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REVIEW ARTICLES

Preclinical efficacy and mechanisms of mesenchymal stem cells in animal models of autoimmune diseases.
Lee HK, Lim SH, Chung IS, Park Y, Park MJ, Kim JY, Kim YG, Hong JT, Kim Y, Han SB.
Immune Netw. 2014 Apr;14(2):81-8. doi: 10.4110/in.2014.14.2.81. Epub 2014 Apr 21. Review.
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Adult stem cells in the treatment of autoimmune diseases.
van Laar JM, Tyndall A.
Rheumatology (Oxford). 2006 Oct;45(10):1187-93. Epub 2006 Jun 15. Review.
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Successes and failures of stem cell transplantation in autoimmune diseases.
Tyndall A.
Hematology Am SocHematolEduc Program. 2011;2011:280-4. doi: 10.1182/asheducation-2011.1.280. Review.
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Mesenchymal stem cell-based therapies in regenerative medicine: applications in rheumatology.
Maumus M, Guérit D, Toupet K, Jorgensen C, Noël D.
Stem Cell Res Ther. 2011 Mar 18;2(2):14. doi: 10.1186/scrt55. Review.
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The use of stem cells for the treatment of autoimmune diseases.
Rosa SB, Voltarelli JC, Chies JA, Pranke P.
Braz J Med Biol Res. 2007 Dec;40(12):1579-97. Epub 2007 Oct 29. Review.
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Intense immunosuppression and stem-cell transplantation for patients with severe rheumatic autoimmune disease: a review.
Van Laar JM, Tyndall A.
Cancer Control. 2003 Jan-Feb;10(1):57-65. Review.
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Immune ablation and stem-cell therapy in autoimmune disease. Clinical experience.
Tyndall A, Gratwohl A.
Arthritis Res. 2000;2(4):276-80. Epub 2000 May 26. Review.
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Hematopoietic stem cell transplantation: a new therapy for autoimmune disease.
Burt RK, Traynor AE.
Oncologist. 1999;4(1):77-83. Review.
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Last modified: Oct 14, 2014
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