Non-Ischemic Cardiomyopathy

 

HUMAN STUDIES

A pilot trial to assess potential effects of selective intracoronary bone marrow-derived progenitor cell infusion in patients with nonischemic dilated cardiomyopathy: final 1-year results of the transplantation of progenitor cells and functional regeneration enhancement pilot trial in patients with nonischemic dilated cardiomyopathy.
Fischer-Rasokat U, Assmus B, Seeger FH, Honold J, Leistner D, Fichtlscherer S, Schächinger V, Tonn T, Martin H, Dimmeler S, Zeiher AM.
Circ Heart Fail. 2009 Sep;2(5):417-23. doi: 10.1161/CIRCHEARTFAILURE.109.855023. Epub 2009 Jul 29.
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Early results of bone marrow cell transplantation to the myocardium of patients with heart failure due to Chagas disease.
Vilas-Boas F, Feitosa GS, Soares MB, Mota A, Pinho-Filho JA, Almeida AJ, Andrade MV, Carvalho HG, Dourado-Oliveira A, Ribeiro-dos-Santos R.
Arq Bras Cardiol. 2006 Aug;87(2):159-66. Portuguese.
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A safety and feasibility study of cell therapy in dilated cardiomyopathy.
Martino HF, Oliveira PS, Souza FC, Costa PC, Assunção E Silva E, Villela R, Gaze M, Weitzel LH, Oliveira A Jr, Muccillo FB, Arvelo SN, Sá R, Guimarães TC, Tura BR, Campos de Carvalho AC.
Braz J Med Biol Res. 2010 Oct;43(10):989-95. Epub 2010 Sep 2
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Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up.
Vrtovec B, Poglajen G, Lezaic L, Sever M, Domanovic D, Cernelc P, Socan A, Schrepfer S, Torre-Amione G, Haddad F, Wu JC.
Circ Res. 2013 Jan 4;112(1):165-73. doi: 10.1161/CIRCRESAHA.112.276519. Epub 2012 Oct 12.
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Comparison of transendocardial and intracoronary CD34+ cell transplantation in patients with nonischemic dilated cardiomyopathy.
Vrtovec B, Poglajen G, Lezaic L, Sever M, Socan A, Domanovic D, Cernelc P, Torre-Amione G, Haddad F, Wu JC.
Circulation. 2013 Sep 10;128(11 Suppl 1):S42-9. doi:10.1161/CIRCULATIONAHA.112.000230.

Effects of intracoronary stem cell transplantation in patients with dilated cardiomyopathy.
Vrtovec B, Poglajen G, Sever M, Lezaic L, Domanovic D, Cernelc P, Haddad F, Torre-Amione G.
J Card Fail. 2011 Apr;17(4):272-81. doi: 10.1016/j.cardfail.2010.11.007. Epub 2010 Dec 24.

Granulocyte-colony stimulating factor or granulocyte-colony stimulating factor associated to stem cell intracoronary infusion effects in non ischemic refractory heart failure.
Bocchi EA, Bacal F, Guimarães G, Mendroni A, Mocelin A, Filho AE, Dores da Cruz Fd, Resende MC, Chamone D.
Int J Cardiol. 2010 Jan 7;138(1):94-7. doi: 10.1016/j.ijcard.2008.06.002. Epub 2008 Aug 1.

Intramyocardial angiogenic cell precursor injection for cardiomyopathy.
Arom KV, Ruengsakulrach P, Jotisakulratana V.
Asian Cardiovasc Thorac Ann. 2008 Apr;16(2):143-8.

Effects of intracoronary stem cell transplantation in patients with dilated cardiomyopathy.
Vrtovec B, Poglajen G, Sever M, Lezaic L, Domanovic D, Cernelc P, Haddad F, Torre-Amione G.
J Card Fail. 2011 Apr;17(4):272-81. doi: 10.1016/j.cardfail.2010.11.007. Epub 2010 Dec 24.


PRECLINICAL STUDIES

c-Kit-positive cardiac stem cells nested in hypoxic niches are activated by stem cell factor reversing the aging myopathy.
Sanada F, Kim J, Czarna A, Chan NY, Signore S, Ogórek B, Isobe K, Wybieralska E, Borghetti G, Pesapane A, Sorrentino A, Mangano E, Cappetta D, Mangiaracina C, Ricciardi M, Cimini M, Ifedigbo E, Perrella MA, Goichberg P, Choi AM, Kajstura J, Hosoda T, Rota M, Anversa P, Leri A.
Circ Res. 2014 Jan 3;114(1):41-55. doi: 10.1161/CIRCRESAHA.114.302500. Epub 2013 Oct 29.
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Transplantation of mesenchymal stem cells improves cardiac function in a rat model of dilated cardiomyopathy.
Nagaya N, Kangawa K, Itoh T, Iwase T, Murakami S, Miyahara Y, Fujii T, Uematsu M, Ohgushi H, Yamagishi M, Tokudome T, Mori H, Miyatake K, Kitamura S.
Circulation. 2005 Aug 23;112(8):1128-35. Epub 2005 Aug 15.
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Study of Adipose Tissue-Derived Mesenchymal Stem Cells Transplantation for Rats with Dilated Cardiomyopathy.
Li L, Xia Y.
Ann Thorac Cardiovasc Surg. 2014 Feb 4. [Epub ahead of print]
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Effects of age and heart failure on human cardiac stem cell function.
Cesselli D, Beltrami AP, D'Aurizio F, Marcon P, Bergamin N, Toffoletto B, Pandolfi M, Puppato E, Marino L, Signore S, Livi U, Verardo R, Piazza S, Marchionni L, Fiorini C, Schneider C, Hosoda T, Rota M, Kajstura J, Anversa P, Beltrami CA, Leri A.
Am J Pathol. 2011 Jul;179(1):349-66. doi: 10.1016/j.ajpath.2011.03.036. Epub 2011 May 19.
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REVIEW ARTICLES

Future prospects for regenerated heart using induced pluripotent stem cells.
Fujita J, Fukuda K.
J Pharmacol Sci. 2014 May 20;125(1):1-5. Epub 2014 Apr 16.
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Endogenous cardiac stem cells for the treatment of heart failure.
Fuentes T, Kearns-Jonker M.
Stem Cells Cloning. 2013 Mar 25;6:1-12. eCollection 2013. Review.
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Mesenchymal stem cells for regenerative therapy: optimization of cell preparation protocols.
Ikebe C, Suzuki K.
Biomed Res Int. 2014;2014:951512. doi: 10.1155/2014/951512. Epub 2014 Jan 6.
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Role of cardiac stem cells in cardiac pathophysiology: a paradigm shift in human myocardial biology.
Leri A, Kajstura J, Anversa P.
Circ Res. 2011 Sep 30;109(8):941-61. doi: 10.1161/CIRCRESAHA.111.243154. Review
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Last modified: Aug 20, 2014
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