COVID Data Resources

May 8, 2020 COVID i2b2 & Data Informational Session

Slides

COVID-19+ Cohort at KUMC

Cohort Information

• Data refreshed weekly
• Cohort includes all patients seen at TUKHS since 1/1/2020 who have been tested for COVID-19 or who have had a diagnosis code for illnesses such as COVID, pneumonia, influenza, bronchitis or fever.

Data Request Process

1. Obtain IRB Approval or Quality Improvement Letter of Determination
2. Build HERON Query
   • HERON team will limit cohort to COVID positive or tested patients
3. Log HERON Data Use or Recruitment Request
   • Request form available at https://heron.kumc.edu (accessible at KUMC or via the KUMC VPN)
   • Please specify if the query should be limited to COVID + or all patients tested for COVID
4. HERON Team & Data Request Oversight Committee will Review Request
   • All individuals listed on the request must sign the data use agreement on the HERON homepage
5. Data Provided in REDCap

COVID-19+ Cohort within The Greater Plains Collaborative (GPC)

The Greater Plains Collaborative (GPC) is a network of 12 leading medical centers in 9 states committed to a shared vision of improving healthcare delivery through ongoing learning, adoption of evidence - based practices, and active research dissemination.

1. Prototype query locally against i2b2 or PCORnet CDM
   • If planning to supersize request to the GPC, pulling data from the PCORnet CDM will be easiest to replicate across sites
2. Log GPC Feasibility or Data Request
   • Request form found on www.gpcnetwork.org
3. GPC Data Request Oversight Committee will review request
4. Data will be provided in REDCap from each participating site

** Funding is required to request line-item GPC data. Feasibility counts are provided for free to support grant applications (as long as no custom work is needed).

National and International Data Efforts:

1. 4CE Consortium is an international consortium for electronic health record (EHR) data-driven studies of the COVID-19 pandemic, led by the i2b2 international academics users group
   • The goal is to inform doctors, epidemiologists and the public about COVID-19 patients with data acquired through the health care process.
   • First preprint published from findings on EHR data from 96 hospitals in the US, France, Italy, Germany, and Singapore
     • International Electronic Health Record-Derived COVID-19 Clinical Course Profiles: The 4CE Consortium
     • Data available for download: https://covidclinical.net/data/index.htm
2. ACT Network
   • Funded by NCATS to support cohort discovery for multicenter trials
     • Feasibility counts run on over 125 million patient records from 44 sites in the CTSA network 
     • Queries return counts from each site
   • 9 sites (BIDMC, Partners, UPitts, UCSD, UTSW, UCLA, USC, KUMC, UAB) have participated in a test network for COVID-19 patients
   • Request access to production ACT on https://heron.kumc.edu 
3. PCORnet COVID-19+ Network
   • PCORnet is a large, highly representative, national patient-centered clinical research network.
   • 20 Patient-Powered Research Network (PPRN), 13 Clinical Data Research Network (CDRN), 2 Health Plan Research Network (HPRD), consists of 329 safety net facilities and 348 health systems
   • 11 CDRNs of 28 sites have participated in the COVID-19+ network