Skip redundant pieces
The Liver Center

Research


liver cells fluorescent image

A major area of interest to the Liver Center is metabolic syndrome. Metabolic syndrome is a combination of medical disorders that increase the risk of heart disease, stroke, and diabetes. The prevalence of metabolic syndrome in the United States is calculated as encompassing up to 25 percent of the population. A compromise in liver metabolism plays a crucial role in the development of metabolic syndrome. Other areas of focus are to define the mechanism for progression of fatty liver to liver cancer; examine the genetic and epigenetic factors that contribute to liver cancer and metabolic diseases; investigate individual differences in liver (drug) metabolism (pharmacogenomics); study the mechanism of alcoholic liver disease and factors for alcohol abuse, and discover new drugs and diagnostic methods to prevent and treat liver cancer and metabolic diseases. The Liver Center also includes research on gastrointestinal disorders and treatment.
Our researchers fall into several categories of liver and GI investigations:

Metabolic Syndrome

Chemical/Alcohol Induced Liver Disease

Liver and GI
Inflammation

Medicinal Chemistry Drug Metabolism

Grace Guo, Ph.D.
Curtis Klaassen, Ph.D.
Prashant Pandya, D.O.
Jeff Staudinger, Ph.D.
Yvonne Wan, Ph.D.
WenFang Wang, Ph.D.
Hao Zhu, Ph.D.

 

 

Udayan Apte. Ph.D.
Bryan Copple, Ph.D.
Curtis Klaassen, Ph.D.
Jim Luyendyk, Ph.D.
Prashant Pandya, D.O.
Yvonne Wan, Ph.D.

Steven Weinman, M.D., Ph.D.

Bashar Abdulkarim, M.D.
Mostafa Badr, Ph.D.
Bryan Copple, Ph.D.
Jameson Forster, M.D.
Richard Gilroy, M.D.
Hartmut Jaeschke, Ph.D.
Curtis Klaassen, Ph.D.
Jim Luyendyk, Ph.D.
Prashant Pandya, D.O.
Michael Parmely, Ph.D.
Amit Rastogi, M.D.
Yvonne Wan, Ph.D. Steven Weinman, M.D., Ph.D.

Jeff Aube, Ph.D.

Robert Hanzlik, Ph.D.

Blake Peterson, Ph.D.

Liver and GI Cancer

Endobiotic/Xenobiotic
Metabolism

Transporters

Pharmacogenomics

Joaquina Baranda, M.D.

Kun Cheng, Ph.D.

Grace Guo, Ph.D.
Bruno Hagenbuch, Ph.D.
Prashant Pandya, D.O.
Emily E. Scott, Ph.D.
Yvonne Wan, Ph.D.

Steven Weinman, M.D., Ph.D.
Stephen Williamson, M.D.
Bao Ting Zhu, Ph.D.

 

 

David Buckley, Ph.D.
Maciej Czerwinski, Ph.D.
Andrea Gaedigk, Ph.D.
Grace Guo, Ph.D.
Gregory Kearns, PharmD, Ph.D.
Curtis Klaassen, Ph.D.
Steven Leeder, PharmD, Ph.D.
Hong Lu, Ph.D.
Andrew Parkinson, Ph.D.
Gregory Reed, Ph.D.
Jeff Staudinger, Ph.D.
Carrie Vyhlidal, Ph.D.
Yvonne Wan, Ph.D.
Xiaobo Zhong, Ph.D.
Bao Ting Zhu, Ph.D.

 

David Buckley, Ph.D.
Bruno Hagenbuch, Ph.D.

Curtis Klaassen, Ph.D.
Partha Krishnamurthy, Ph.D.
Hong Lu, Ph.D.

Kevin Lyon, Ph.D.
Jeff Staudinger

Andrea Gaedigk, Ph.D.
Gregory Kearns, PharmD, Ph.D.
Curtis Klaassen, Ph.D.
Steven Leeder, PharmD, Ph.D.
Carrie Vyhlidal, Ph.D.
Yvonne Wan, Ph.D.
Xiaobo Zhong, Ph.D.

Clinical Research & Support

Liver Regeneration

Bile Acids

Metabolomics

Bashar Abdulkarim, M.D.
Ivan Damjanov, M.D., Ph.D.

James Daniel, M.D.
Jameson Forster, M.D.
Richard Gilroy, M.D.
Gregory Kearns, PharmD, Ph.D.

Ding-You Li, M.D.
Atta Nawabi, M.D.

Mojtaba Olyaee, M.D.
Prashant Pandya. D.O.

Prabhu Parimi, M.D.
Gregory Reed, Ph.D.
G. Sitta Sittampalam, Ph.D.
Ossama Tawfik, M.D., Ph.D.
Ryan Taylor, M.D.

Steven Weinman, M.D., Ph.D.
Scott Weir, PharmD, Ph.D.
Stephen Williamson, M.D.

Bashar Abdulkarim, M.D.
Udayan Apte, Ph.D.
Richard Gilroy, M.D.
Hartmut Jaeschke, Ph.D.
Curtis Klaassen, Ph.D.
Jennifer Laurence, Ph.D.
Mojtaba Olyaee, M.D.
Ryan Taylor, M.D.
Gregory Vanden Heuvel, Ph.D.
Yvonne Wan, Ph.D.

Bryan Copple, Ph.D.
Grace Guo, Ph.D.
Bruno Hagenbuch, Ph.D.
Curtis Klaassen, Ph.D.

Xiaochao Ma, Ph.D.

 


When we try to pick out anything by itself, we find it is tied to everything else in the universe.

John Muir (1838-1914)