A major area of interest to the Liver Center is metabolic syndrome. Metabolic
syndrome is a combination of medical disorders that increase the risk
of heart disease, stroke, and diabetes. The prevalence of metabolic syndrome
in the United States is calculated as encompassing up to 25 percent of
the population. A compromise in liver metabolism plays a crucial role
in the development of metabolic syndrome. Other areas of focus are
to define the mechanism for progression of fatty liver to liver cancer;
examine the genetic and epigenetic factors that contribute to liver cancer
and metabolic diseases; investigate individual differences in liver (drug)
metabolism (pharmacogenomics); study the mechanism of alcoholic liver
disease and factors for alcohol abuse, and discover new drugs and diagnostic
methods to prevent and treat liver cancer and metabolic diseases. The
Liver Center also includes research on gastrointestinal disorders and
treatment.
Our researchers fall into several categories of liver and GI investigations:
Metabolic
Syndrome |
Infectious, Alcohol and Drug Induced Liver Injury |
Liver and
GI
Inflammation |
Medicinal Chemistry Drug Metabolism |
Winston Dunn, M.D.
Grace
Guo, Ph.D.
Curtis
Klaassen, Ph.D.
Prashant Pandya, D.O.
Jeff
Staudinger, Ph.D.
Yu-Jui Yvonne
Wan, Ph.D.
WenFang Wang, Ph.D.
Hao Zhu, Ph.D.
|
Udayan Apte. Ph.D.
Bryan
Copple, Ph.D.
Wen-Xing Ding, Ph.D.
Winston Dunn, M.D.
Severin Gudima, Ph.D.
Curtis
Klaassen, Ph.D.
Jim
Luyendyk, Ph.D.
Prashant Pandya, D.O.
Yu-Jui Yvonne
Wan, Ph.D.
Steven Weinman, M.D./Ph.D.
|
Bashar Abdulkarim, M.D.
Mostafa Badr, Ph.D.
Bryan Copple, Ph.D.
Jameson Forster, M.D.
Richard Gilroy, M.D.
Hartmut
Jaeschke, Ph.D.
Curtis
Klaassen, Ph.D.
Jim Luyendyk, Ph.D.
Prashant Pandya, D.O.
Michael Parmely, Ph.D.
Amit Rastogi, M.D.
Yu-Jui Yvonne
Wan, Ph.D.
Steven Weinman, M.D., Ph.D. |
Jeff Aube, Ph.D.Robert Hanzlik, Ph.D. Blake Peterson, Ph.D.
|
Liver and
GI Cancer |
Endobiotic/Xenobiotic
Metabolism |
Transporters |
Pharmacogenomics |
Joaquina Baranda, M.D.
Kun Cheng, Ph.D.
Grace Guo, Ph.D.
Bruno Hagenbuch, Ph.D.
Prashant Pandya, D.O.
Emily E. Scott, Ph.D.
Yu-Jui Yvonne
Wan, Ph.D.
Steven Weinman, M.D., Ph.D.
Stephen Williamson, M.D.
Bao Ting Zhu, Ph.D.
|
Maciej Czerwinski, Ph.D.
Grace
Guo, Ph.D.
Gregory Kearns, PharmD, Ph.D.
Curtis
Klaassen, Ph.D.
Steven Leeder, PharmD, Ph.D.
Hong Lu, Ph.D.
Andrew Parkinson, Ph.D.
Gregory Reed, Ph.D.
Jeff
Staudinger, Ph.D.
Carrie Vyhlidal, Ph.D.
Yu-Jui Yvonne Wan, Ph.D.
Xiaobo
Zhong, Ph.D.
Bao
Ting Zhu, Ph.D.
Xiaochao Ma, Ph.D.
|
Bruno
Hagenbuch, Ph.D.
Curtis
Klaassen, Ph.D.
Partha Krishnamurthy, Ph.D.
Jed Lampe, Ph.D.
Hong Lu, Ph.D.
|
Andrea Gaedigk, Ph.D.
Gregory Kearns, PharmD, Ph.D.
Curtis Klaassen, Ph.D.
Steven Leeder, PharmD, Ph.D.
Carrie Vyhlidal, Ph.D.
Yu-Jui Yvonne
Wan, Ph.D.
Xiaobo Zhong, Ph.D. |
Clinical
Research & Support |
Liver Regeneration |
Bile Acids |
Metabolomics |
Bashar
Abdulkarim, M.D.
Ivan Damjanov, M.D., Ph.D.
James Daniel, M.D.
Winston Dunn, M.D.
Jameson Forster, M.D.
Richard Gilroy, M.D.
Gregory Kearns, PharmD, Ph.D.
Ding-You Li, M.D.
Atta Nawabi, M.D.
Mojtaba Olyaee, M.D.
Prashant Pandya. D.O.
Prabhu Parimi, M.D.
Gregory
Reed, Ph.D.
G.
Sitta Sittampalam, Ph.D.
Ossama Tawfik, M.D., Ph.D.
Ryan Taylor, M.D.
Steven Weinman, M.D., Ph.D.
Scott Weir, PharmD, Ph.D.
Stephen
Williamson, M.D.
|
Bashar
Abdulkarim, M.D.
Udayan Apte, Ph.D.
Richard Gilroy, M.D.
Hartmut
Jaeschke, Ph.D.
Curtis
Klaassen, Ph.D.
Jennifer Laurence, Ph.D.
Mojtaba
Olyaee, M.D.
Ryan Taylor, M.D.
Gregory Vanden Heuvel, Ph.D.
Yu-Jui Yvonne
Wan, Ph.D. |
Bryan
Copple, Ph.D.
Grace
Guo, Ph.D.
Bruno Hagenbuch, Ph.D.
Curtis
Klaassen, Ph.D. |
Xiaochao Ma, Ph.D. |
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The University of Kansas Medical Center