[List of Publications]                         [Professional Data]
Cristian Saez, PhD
Assistant Lab Director
Heritage Labs, LLC
111 West Old 56 Hwy.
Olathe, Kansas 66061
(913) 764-1045
csaez@heritagelabs.com cs@diagnomedica.com
















PUBLICATIONS

  1. Burzio, L.O., Gutierrez, E., De la Fuente, E., Saez, C., Brito, M., Pardo, J., Burzio, L.A., Burzio, V.A. & Weiss, R. (1989) Marine Bioadhesives: Projections in Medicine and Industry. In: Current Topics in Marine Biotechnology. (Edited by Miyachi, S., Karube, I. and Ishida, Y.) pp. 353-356. The Japanese Soc. Marine Biotechnology, Tokyo.

  2. Burzio, L.O., Gutierrez, E., Pardo, J., De la Fuente, E., Brito, M. & Saez, C. (1990) Bioadhesives: A Biotechnological Opportunity. Ach.Biol.Med.Exp. 23, 173-178. Abstract

  3. Pardo, J., Gutierrez, E., Saez, C., Brito, M. & Burzio, L.O. (1990) Purification of Adhesive Proteins from Mussels. Protein Expression and Purification 1, 147-150. Abstract

  4. Saez, C., Gutierrez, E., Brito, M. & Burzio, L.O. (1991) Immunological Studies of Polyphenolic Proteins of Mussels. Comp. Biochem. Physiol II 98, 569-572. PDF reprint

  5. Saez, C., Jensen, G., Smith, A. & Morgan, W.T. (1995) Interaction of Histidine-Proline-Rich Glycoprotein with Plasminogen: Effect of Ligands, pH, ionic strength and Chemical Modification. Biochemistry 34, 2496-2503.
    Abstract

  6. Henzl, M.T., Zhao, H. & Saez, C. (1995) Self-Association of CPV3, an Avian Thymic Parvalbumin. FEBS Letters 375, 37-142. Abstract

  7. Saez, C., Thielens, N.M., Bjes, E.S. & Esser, A.F. (1999) Association of Terminal Complement Proteins in Solution and Modulation by Suramin. Biochemistry 38, 6807-6816. Abstract

  8. Burzio, L.A., Saez, C., Pardo, J., Waite, J.H. & Burzio, L.O. (2000) The adhesive protein of Choromytilus chorus (Molina, 1782) and Aulacomya ater (Molina, 1782): a proline-rich and a glycine-rich polyphenolic protein. Biochim Biophys Acta 1479, 315-320.Abstract

  9. Mukherjee A, Saez, C., Lutkenhaus J. (2001) Assembly of an FtsZ mutant deficient in GTPase activity has implications for FtsZ assembly and the role of the Z ring in cell division. J Bacteriol 183, 7190-7197. Abstract

  10. Hu, Z., Saez, C., Lutkenhaus J. (2003) Recruitment of MinC, an inhibitor of Z-ring formation, to the membrane in Escherichia coli: role of MinD and MinE.J Bacteriol 185, 196-203. Abstract
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PROFESSIONAL DATA
    - EDUCATION

    - POSITIONS

    Industrial Positions:
  • Bioanalytical Chemist
    Department of Quality Control
    Sterling-Winthrop, Inc.
    Santiago, Chile
    1987
    - PROFESSIONAL SOCIETIES

    - SPECIALIZED SKILLS

    Chemical/Biochemical Instrumentation

    Several analytical techniques, including IEF, and continuous FF electrophoresis; HPLC/EC of polymers and low molecular weight compounds; conventional techniques of chromatography (Column, TLC,GLC); UV-Vis, CD, IR, and fluorescence spectroscopy. Experienced with most analytical chemistry instrumentation such as Karl Fisher, viscosimetry, densitometry and mass spectrometry.

    Chemical/Biochemical Methods

    Experienced in traditional protein chemistry methods such as SDS-PAGE, Western blot, moderate scale protein purification, antisera production, immunochemical techniques and enzyme assays and implementation of novel methods. Relevant experience in methods to analyze macromolecular interactions such as analytical ultracentrifugation, multiangle laser light scattering (MALLS) photometry, microcalorimetry (ITC/DSC) and optical biosensors.

    Molecular Biology Methods

    Familiar with most recombinant DNA techniques such as PCR, northern blot, expression libraries, site directed mutagenesis. Experienced with most microbiological techniques.

    Industrial Experience

    Background in QC/QA of pharmaceuticals. Experience in statistical methods, computer-based analysis of data and abstracting for technical publications. Familiar with basic GLP/GMP and safety regulations.

    Computer Skills

    Proficient in many software applications including data-bases, editors, graphics and image processing using any computer platform. Working knowledge of HTML and internet related applications.

    - TECHNICAL TRAINING

  • Training in Laser Light Scattering. Wyatt Technology Corporation. Santa Barbara, California, April 1998.

  • Training in Molecular Cloning. Walther Cancer Institute, University of Notre Dame, Notre Dame, Indiana,
    October 1997 - February 1998.

  • Training in Microcalorimetry. Biocalorimetry Center, The Johns Hopkins University, Baltimore, Maryland,
    June 1997.

  • Training in Analytical Ultracentrifugation. Department of Research and Applications, Spinco Division,
    Beckman Coulter, Inc. Palo Alto, California, October 1993.

  • Training in Glycobiology. W. Colli & R. Lederkremer. Institute of Chemistry, University of Sao Paulo,
    Brazil. November 1992.

  • Training in Bacterial Genetics.Department of Molecular Genetics and Microbiology , Pontificial Catholic
    University of Chile.     September 1990.

  • Training in Statistical Methods: Computer Oriented Analysis, Department of Statistics. Pontificial Catholic
    University of Chile. January 1986.
    - FELLOWSHIPS AND AWARDS

  • Postdoctoral Fellowship. Walther Cancer Foundation. Indiana 1997.

  • National Science Foundation Travel Award. November 1997.

  • Training Fellowship. UNESCO and Latin American Network for Biological Sciences (RELAB). Brazil, 1992.

  • Predoctoral Fellowship. National Commission of Science and TechnologyCHILE. 1989-1992.
    - MEETINGS
  • -42th Annual Meeting of the Biophysical Society. Kansas City, Missouri, February 1998. Biophys. J. 74 (2), A365. Contributed paper.

  • -First Beckman Symposium on Solution Interaction of Macromolecules. Galveston, Texas, November 1997. Contributed paper.

  • -Joint Meeting of the American Society for Biochemistry and Molecular Biology (ASBMB)-DBC of the American Chemical Society. San Francisco, California, May 1995. FASEB J. 9(6), A1465. Contributed paper.

  • -85th Annual Meeting of the American Society for Biochemistry and Molecular Biology (ASBMB). Washington, D.C., May 1994. FASEB J. 8(7), A1295. Contributed paper.

  • -Second Aging Symposium of the Scientific Education Partnership (SEP) Foundation. Kansas City, Missouri, May 1994. Program book pp. 58. Contributed paper.

  • -Second National Meeting of Biotechnology; CNB, CONICYT-CHILE Viņa del Mar, April 1991. Program book pp. R87. Contributed paper.

  • -32th Annual Meeting of the Chilean Society for Biology. Viņa del Mar, November 1989. Arch. Biol. Med. Exp. 22, R300. Contributed paper.

  • -First International Conference of Marine Biotechnology. Tokyo-Japan. September 1989. Conference book, pp. 353. Contributed paper.

  • -First National Meeting of Biotechnology; CNB, CONICYT-CHILE Talca, January 1989. Program book, pp. R28. Contributed paper.

  • -31th Annual Meeting of the Chilean Society for Biology La Serena, November 1988. Arch. Biol. Med. Exp. 21, R329. Contributed paper.

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