Employees of the Department enjoy benefits provided to all faculty and unclassified employees by the Kansas Board of Regents. Details about employment at KUMC can be found at the KUMC Human Resources website.

All applications, unless noted otherwise, should be submitted online only via http://jobs.kumc.edu, referring to the respective position number.

NEW: Postdoctoral Fellow (Gudima Laboratory) – J0040060

The laboratory of Dr. Severin Gudima at University of Kansas Medical Center (KUMC) studies pathogenesis and mechanism of infection of human hepatitis B virus (HBV) and human hepatitis delta virus (HDV). One position in Dr. Gudima’s lab is available for highly motivated and goal-oriented scientist to study molecular aspects of HDV pathogenesis and interference between HBV and HDV during the infection of human hepatocytes. Areas of expertise include virology, molecular biology, microbiology, cell culture, cloning, protein expression and purification. Experience in RNA virology, infection of primary hepatocytes, viral assembly and replication, expression of viral proteins in mammalian cells will be a plus. The position requires active participation in writing manuscripts and grants and ability to conduct mostly independent research. Required Qualifications: Ph.D. in Virology, Molecular Biology, Microbiology, or other related discipline. Preferred Qualifications: Peer-reviewed publications demonstrating significant accomplishments in biomedical research. Estimated Start Date: July 2009.

Postdoctoral Fellow (Mir Laboratory) – J00200850

The laboratory of Dr. Mohammad Ayoub Mir at Kansas University Medical Center studies virus-host interaction with a focus on transcription and translation initiation of viral mRNA. We have recently found that hantavirus nucleocapsid protein (N) prevents the degradation of mRNA 5’ caps by cellular decapping machinery. Rescued capped oligoes are stored in cellular P-bodies and are later used as primers by viral RNA dependent RNA polymerase for the synthesis of viral mRNA (Mir MA, et al Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19294-9). N is also a multifunctional translation initiation factor that recruits small ribosomal subunit at mRNA 5’ caps and preferentially facilitates translation of capped mRNAs. N functionally supplants cellular eIF4F cap binding complex (Mir MA et al, EMBO J. 2008 Dec 3;27(23):3129-39). Two positions in Dr. Mir’s lab are available for highly motivated and creative scientists to study transcription and translation initiation of Hantaviral mRNA. One project focuses on the molecular mechanism for the generation of capped RNA primers during “cap-snatching”. Another project studies how N mediated translation initiation benefits virus replication in infected cells. Areas of expertise include molecular biology, microbiology, tissue culture, cloning, protein expression and purification. Experience in virology, transcription, translation and RNA polymerases will be preferred. Thse positions also require self-motivated participation in activities such as grant and manuscript writing and general laboratory upkeep. Required Qualifications: Ph.D. in Molecular Biology, Biochemistry, Cell Biology, Microbiology, Virology or other related life science discipline. Preferred Qualifications: Peer-reviewed publications demonstrating high achievement in biomedical research. Experience with recombinant DNA technology, virology, transcription, translation and RNA polymerases. Estimated Start Date: August 2009.

The University of Kansas Medical Center is an equal opportunity/affirmative action employer. Applications are sought from all qualified people regardless of sex, race, color, religion, sexual orientation, disability, national origin, veteran status, ancestry or age. To request accommodation in the application process, contact 913/588-1206. Persons with speech or hearing impairments may access the Kansas State Relay at 800/766-3777.

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