Female Reproductive System

Copyright 1996 The University of Kansas Medical Center

Department of Anatomy and Cell Biology

Primordial Follicle
(Primary oocyte with 1 layer of follicular cells)

Primary Follicle
(Oocyte enlarged, follicular cells cuboidal and now called 'granulosa cells', zona granulosa present)

Secondary Follicle
(Follicular antrum appears in the zona granulosa, theca interna & externa develops)

Graafian Follicle
(Antrum greatly enlarged, secondary oocyte surrounded by corona radiata)