DNA Model and Protein Synthesis

Teacher: Christine Petit
Subject: Genetics
Grade Level(s): 9 10 11 12
Target Audience: Biology I & II
Materials Needed: wide tip markers, computer paper tear strips, 16 ga. wire, adhesive tape, white glue, toothpicks, paper, post-it note sheets
Class Time: 2-3 55 minute class periods
Brief Summary: Students build a 3-dimensional model of DNA coding for the hormone oxytocin.
Student Objective(s): Realize the three-dimensional double helix structure of DNA. (Optional exercise for transcription and translation.)
Integration (tying it all together): The deoxyribose-phosphate molecules alternate to form the backbones of the molecule and are constant in each DNA molecule. Base pairing of AT and CG is specific, but will vary in order to provide variety and specificity for proteins. Compare DNA structure to that of mRNA and tRNA commenting on transcription and translation.
Description of Activities: Review DNA structure and function. Hand out and describe DNA construction instructions. Question students on DNA structure and function with the completed models. Optional transcription and translation activity.
Further Information and References: The Biotechnology Education Project, St. Louis Mathematics and Science Education Center, 1990, 8001 Natural Bridge Rd., St. Louis, MO 63121

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