The Institutional Biosafety Committee (IBC) works closely with the Human Subjects Committee (HSC) who acts as KUMC's Institutional Review Board (IRB) in regards to research involving humans. The committee also works closely with the Institutional Animal Care & Use Committee (IACUC) in regards to research involving research. Diligently fostering an open line of communication between all the above mentioned parties is vital to ensure that research is conducted in a manner consistent with the biosafety practices outlined within both accepted industry standards and mandatory regulations.
The committee meets monthly and welcomes public citizens to attend. The meeting dates for 2016 are found below. If you are interested in attending a meeting, please contact Charles Cherrito at firstname.lastname@example.org or 913-588-5206.
IBC Policy & IBC Procedures
The IBC policy establishes the University of Kansas Medical Center ("KUMC") Institutional Biosafety Committee and sets forth requirements for the safe and secure use of recombinant or synthetic nucleic acid molecules and other biohazardous agents, materials and toxins in compliance with relevant laws, regulations and guidelines. The policy can be found here.
The IBC procedure sets forth the requirements for review, approval and oversight of the use of recombinant or synthetic nucleic acid molecules in teaching, research or testing activities conducted by KUMC facilities or research personnel. All such activity, regardless of funding source, must be conducted in accordance with the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines). The policy can be found here.
Below are the most current definitions regarding each topic pertinent for review from the IBC. The definitions are directly from each federally governing body.
Recombinant DNA (rDNA) & Synthetic DNA
In the context of the NIH Guidelines, recombinant and synthetic nucleic acids are defined as:
1. molecules that are constructed by joining nucleic acid molecules and can replicate in a living cell
2. nucleic acid molecules that are chemically or by other means synthesized or amplified, including those that are chemically or otherwise modified but can base pair with naturally occurring nucleic acid molecules
3. molecules that result from the replication of those described in 1 or 2 above
Select Pathogenic Agents and/or Toxins (BSAT)
Biological select agents and toxins are a subset of agents that the United States Departments of Health and Human Services (HHS) and Agriculture (USDA) have determined to have the potential to pose a severe threat to public health and safety, to animal or plant health, or to animal or plant products.
An etiologic agent is defined as being any kind of microorganism that can cause a human to develop a disease. The definition includes microorganism like bacteria and viruses. Etiologic agents are also referred to as toxins.