Researcher Resource Request

Helping investigators do innovative research is a central function of the KU ADC. We provide consultation, services, or research materials to investigators.

Available Resources

The KU ADC can support the following research requests:

Access to well characterized AD, mild cognitive impairment and aging control populations and banked AD and control subject biospecimens, including:

• Brain Tissue
• Buffy Coat
• Cell-free Plasma
• Cybrid Cell Lines
• DNA
• RNA
• Muscle
• Plasma
• Platelets
• Serum
• Whole Blood

Access to and assistance with existing datasets, including:

• Alzheimer's Disease Neuroimaging Initiative
• National Alzheimer's Coordinating Committee Database
• University of Kansas Brain Aging Project

The KU ADC specializes in metabolism and mitochondrial function and has expertise in:

• Physical fitness, glucose tolerance, metabolic rate, and body composition testing
• Structural brain neuroimaging of humans and animals
• Metabolic neuroimaging of humans and animals, including FDG PET, AV-45 and MRS
• Biochemical assays
• Platelet mitochondria enzyme activities, mitochondria O₂ consumption, mitochondrial DNA heteroplasmy detection
• Production and characterization of transmitochondrial hybrid cell lines
• Brain protein aggregation assessments
• WBC gene expression and gene sequencing
• Cytoplasmic hybrid cell line creation and characterization