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Complex Object Parametric Analyzer and Sorter (COPAS) PLUS Biosorter Instrument The COPAS platform is designed for the in-flow measurement of objects ranging in size from 20 – 1500 microns. Each model features a specially engineered fluidic path and flow cell optimized for a specific subset of that size range to provide maximum speed, accuracy, and throughput depending on application. Most instruments can dispense objects either in bulk receptacles or multiwell plates.
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Metabolic Modular Treadmill The Modular Treadmill encloses each animal within an isolated space. An exercise belt, associated pulleys, a fan to promote air movement and electric stimuli are enclosed in a compartment which is made air-tight. The addition of an indirect open circuit calorimeter to the compartment creates a complete system for the measurement of respiratory metabolic performance during animal exercise. The system is constructed of master and slave units. A master unit incorporates an electric motor and speed controller to which one to seven additional slave units can be connected for exercising multiple animals. The incline of each animal compartment is individually adjustable in 5 degree increments. Electrical stimulus grids in each exercise lane can be activated manually by the operator. Intensity of electrical shock is also operator adjustable from 0.35mA to 1.5mA. LED lamps indicate which electrical stimulus grid is active.
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EcoOxymax Small Animal Calorimeter This is an indirect open circuit calorimeter designed to measure the metabolic performance of a single subject. The system monitors oxygen and carbon dioxide concentrations by volume at the inlet and outlet ports of a chamber, canopy, tent, or mask through which a known flow of air is being forcibly ventilated. The difference in gas concentrations along with flow information is employed to calculate oxygen consumption, carbon dioxide production, respiratory exchange ratio and heat. All data provided by the Oxymax Eco is corrected to an STP of 0° and 760 mmHg. The system presents data in normalized forms that are user-defined. The Oxymax Eco can be configured for positive or negative ventilation of a single subject. Flows between 100 mL/Min and 15,000 LPM are supported. The instrument supports all of the facilities of the Oxymax Equal Flow System with the limitation of working with only a single subject. The Oxymax Eco can be upgraded to support multiple subjects and provides a low cost entry into calorimetric measurements while providing the possibility of adding features to meet increasing demand.
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MPVS-400 Pressure-Volume Unit The MPVS-400 (910-1054) pressure-volume signal conditioning hardware has a four-channel PowerLab data acquisition system integrated in the single unit. The MPVS-400 is supplied with LabChart software for pressure and volume data acquisition and analysis and comes with adjustable gain settings for use in ex vivo studies involving solutions with varying conductivity values. |
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Millar Pressure-Volume catheter Millar Mikro-Tip Pressure-Volume catheters have revolutionized cardiovascular research in small animals. These ultra-miniature catheters are capable of measuring both ventricular pressure and volume simultaneously and continuously from the intact beating hearts of rats and mice. The SPR-838 is an ultra-miniature Pressure-Volume Catheter (2.0F Polyimide Nylon) suitable for use in rats with an effective length of 12.5cm. The pairs of platinum electrodes are separated by 0.5mm with the distance between each pair of 9.0mm. The pressure sensor is located in the center, between the two pairs of electrodes. The catheter uses a low-profile connector for the pressure sensor and redel for the volume conductance. It requires a PEC-4D Catheter Interface Cable for pressure measurement and CEC-4B Connection Cable for Conductance Catheter for connection to the MPVS-300 or MPVS-400 Pressure-Volume Unit. |
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Animal Bio Amp The Animal Bio Amp (ML136) is a galvanically isolated, high performance, software-controlled differential amplifier suitable for the measurement of a wide variety of biological signals in animals and isolated tissues. Three 2mm input sockets allow the direct connection of electrodes to this amplifier. Included with the Animal Bio Amp are MLA1215 Animal Bio Lead Wires however the unit can also be used with MLA1210 Spring Clip Electrodes or MLA1204 Needle Electrodes. Applications: Biopotential measurements, animal ECG, EEG, and EMG as well as cardiac electrical activity in isolated heart experiments. |
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2-D Protein Electrophoresis The Ettan IPGphor II Isoelecrtic Focusing System performs first dimension isoelectric focusing (IEF) in 2-dimensional (2-D) electrophoresis. The system comprises Immobiline DryStrip gel strips, which contain an immobilized pH gradient (IPG); strip holders, which serve as both and IEF chambers for the IPG strips; and the Ettan IGPphor II unit, which includes a high-voltage DC power supply, solid state temperature control, and can be programmed with up to ten user-defined IEF protocols.
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SE 600 Ruby (dual-cooled gel electrophoresis unit) The SE 600 Ruby vertical slab gel electrophoresis unit is intended for protein and nucleic acid electrophoresis under commonly used denaturing and non-denaturing conditions. Up to 28 samples can be compared on a single slab gel. Applications include protein separations, nucleic acid fractionation, and the second-dimension separation of 2-D electrophoresis. First-dimension separation of 2-D protein electrophoresis is performed on Immobiline DryStrip Immobilized pH Gradient Gels using the IPGphor Isoelectric Focusing System. The focused strips are easily transferred to the second-dimension slab gel for size separation. The gel plates are 18 cm wide by 16 cm long. Up to four gels can be run at one time if sandwiches are paired into "club sandwiches." The heat exchanger allows buffer temperature control in the lower chamber. |
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Bio-Rad Trans-Blot Cell (tank transfer system) The Trans-Blot cell is a truly versatile tank transfer system. Flexible electrode placement and variable power conditions allow standard or high-intensity transfers of up to three 16 x 20 cm gels or up to twelve mini format gels simultaneously. |
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FluoView 300 Confocal Microscope The Olympus FluoViewTM 300 is a point-scanning, point-detection, confocal laser scanning microscope designed for biology research applications. Excellent resolution, efficiency of excitation, intuitive user interface and affordability are key characteristics of the Olympus FluoView 300. The FluoView 300 configured permits simultaneous collection of up to 3 detection channels. The FV300 may be configured on either the IX2 inverted research microscope platform or the BX2 upright research microscope platform.
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NuAire Laminar Flow Hood – Class II, Type A2 A Class II ventilated cabinet provides personnel, product and environmental protection. It is characterized by a limited fixed inward Air Flow access opening that provides personnel protection, a vertical downward HEPA filtered work zone that provides product protection and HEPA filtered exhaust providing environmental protection. A Type A2 cabinet maintains a minimum of 100 FPM inflow velocity, self-exhausts approximately 30 percent back into the laboratory, and recirculates the remainder.
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MRXII Microplate Reader
The MRXII is a stand-alone microplate photometer. The on-board software provides comprehensive data handling, and easy data transfer to Excel. It can be upgraded by interfacing it with a computer and using Revelation software to control the instrument and data processing. The MRX family of filter-based absorbance readers provide excellent linearity, accuracy, and precision, supporting endpoint, kinetic, and tissue culture/agglutination assays. With quick read time (less than four seconds for a 96-well plate), single or multiple wavelength reading (340-850 nm), optional temperature control (ambient to 63 degrees C), and built-in self diagnostic routines, the MRXII microplate reader is ideal for a range of clinical and research applications. |
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Nalgene caging Activity Wheel with Mini Mitter magnetic switch Nalgene animal caging provides running wheels that are high quality and durable. They will resist discoloration and maintain their smooth rotation for years of use. They may be autoclaved. Running wheel turns may be monitored manually using a combination of a Mini Mitter Magnetic Switch and a digital switch counter or automatically using the magnetic switch and the VitalView Data Acquisition System. Rat and mouse size wheels are available. The wheel forms a portion of the lid of the cage, the other portion is formed by a food hopper and water bottle holder. Either size wheel may be configured as the lid for a standard domicile cage or as the lid of a cage with a cut-away bottom which allows for easier cleaning.
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Rodent Treadmill Exer 3/6 Exer-3/6 is a general purpose three (rats) or six (mice) lane animal exerciser utilizing single belt construction with dividing walls suspended over the tread surface. Exer-3/6 can be supplied with or without a stimulus assembly. An electrical stimulus system option is composed of three or six shock grids, each with individual on/off switches. Stimulus intensity is adjustable and LED lamps indicate which stimulus grid is active. Design of electrical stimulus grid reflects special attention to avoid injuries to animals. Animals are exercised in three or six compartments made of durable plastic (clear Lexan or opaque PVC). For some applications, users may choose the Exer-3/6 with a single large compartment. An included drive motor controller provides smooth and continuous adjustment of speed in the range 6-100 m/m. The exercising belt is made with special material that facilitates the animals' grip and is easy to clean.
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