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Reference #: YOU-1018-446711
Submit Date: 04/10/2002 08:23:55-0500
Presentation Type: platform
CONTACT: Antony Young
Department of Environmental Dermatology St John[:apos:]s Institute of Dermatology
King[:apos:]s College London London, UK SE1 7EH
The determination of immune protection
factors of sunscreens
AUTHOR GROUP:
Antony Young 1
Department of Environmental Dermatology St John[:apos:]s Institute of Dermatology King[:apos:]s College London London, UK SE1 7EH 1
Anny Fourtanier 2
L[:apos:]Or[:eacute:]al Recherche Clichy, France 92583 2
ABSTRACT:
Recent human studies show that low dose solar simulated UVR is immunosuppressive and it is suspected that such immunosuppression may play a role in skin cancer and immunity to pathogens. The use of sunscreens is widely advocated to reduce skin cancer risk. Assuming that UVR induced immunosuppression plays a role in human skin cancer, it is therefore important to establish the immunoprotective properties of sunscreens and to determine if a product's immune protection factor (IPF) is comparable to its sun protection factor (SPF). The assessment of IPF has proved to be much more difficult than one might have predicted. This school will review the many problems of IPF assessment and propose suggestions for their solution.
Keywords: Immune protection factor, IPF
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