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30th Annual Meeting of the American Society for Photobiology
Fairmont Le Chateau Frontenac
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TUESDAY, JULY 16 |
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| 7:00-9:00am Place D'Armes/ Jacques Cartier |
Continental Breakfast/Exhibits/Poster Viewing 2 | |
| 8:00am-9:00am Salle de Bal |
Photobiology School 3 Light-induced Reactions in Photosynthesis |
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| 9:00am-12:00pm Frontenac |
A5 Photocarcinogenesis Chairs: Hasan Mukhtar, University of Wisconsin, Madison, WI and H. Anathaswamy, Anderson Cancer Center, Houston, TX |
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9:00am
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Non-melanoma Skin Cancer: Current
Incidence Rates and Risk Factors from a Population-based Case-control Study
in New Hampshire M. Karagas, Dartmouth Medical School, Lebanon, NH |
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9:25am
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Late Detection of DNA Damage
and Enhanced UV Carcinogenesis in XP-C 1H. Rebel, 1R. Berg, 1M. van Oosten, 2A.Westerman, 2N. Kram, 1L. Mullenders, 2H. van Kranen, 1F. de Gruijl, 1Leiden University Medical Center, Leiden, Netherlands, 2National Institute of Public Health and the Environment, Bilthoven, Netherlands |
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9:50am
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Cutaneous Cytokine Expression
During Chronic Solar-simulated UV (SSUV) Irradiation of Mouse Skin - Relationship
with Photocarcinogenesis V. Reeve, S. Widyarini, University of Sydney, Sydney, NSW |
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10:15am
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Break | |
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10:45am
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Melanoma in Neonatally UV Irradiated
HGF/SF Transgenic Mice- A Model for Human Disease 1F. Noonan, 2J. Recio, 3M. Anver, 4P.Duray, 1E. De Fabo, 2G. Merlino, 1The George Washington School of Medicine, Washington, DC, 2NIH, Bethesda, MD, 3,4National Cancer Institute, Frederick, MD |
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11:10am
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Green Tea Constituent -epigallocatechin-3-gallate
Inhibits Ultraviolet B-mediated Activation of Nuclear Factor kappa B Signaling
Pathway in Normal Human Epidermal Keratinocytes 1Afaq, 1Adhami, 1Ahmad, 1Mukhtar, University of Wisconsin, Madison, WI |
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11:35am
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Loss of the Unusual Antigenic
Properties in UV-induced Skin Tumors from Mice with no Functional p53 W. Jiang, H. Ananthaswamy, S. Ullrich, M.Kripke, MD Anderson Cancer Center, Houston, TX |
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| 9:00am-12:00pm Salle de Bal |
B5 PDT-elicited Immune Responses Chairs: Mladen Korbelik, B.C. Cancer Agency and Barbara Henderson, Roswell Park Cancer Institute, Buffalo, NY |
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9:00am
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Role of Inflammation in HPPH-PDT B. Henderson, S. Gollnick, Roswell Park Cancer Institute, Buffalo, NY |
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9:25am
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Neutrophil-mediated Oxidative-
and Non-oxidative Stress in Tumors Treated by Photodynamic Therapy 1W. Sluiter, 2M. Korbelik, 2I. Cecic, 1E.de Wit, 1Erasmus, Rotterdam, The Netherlands, 2British Columbia Cancer Agency, Vancouver, B.C., Canada |
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9:50am
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Addressing the Problem of Photodynamic
Therapy-induced Immunosuppression in Cancer Treatment M. Korbelik, British Columbia Cancer Agency, Vancouver, B.C., Canada |
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10:15am
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Break | |
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10:45am
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Dendritic Cell Activation by
PDT Vaccines S. Gollnick, B. Henderson, Roswell Park Cancer Institute, Buffalo, NY |
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11:15am
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Photodynamic Therapy Enhances
both Effector and Regulatory Functions of the Complement System in Murine
Tumor Models I. Cecic, M. Korbelik, British Columbia Cancer Agency, Vancouver, B.C., Canada |
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11:30am
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Endogeneous Expression of Interlerkin 8, Interleukin 10
and Granulocyte Macrophage Colony Stimulating Factor in Nasopharyngeal Carcinoma
Cells and the Effect of Hypericin-mediated PDT 1H. Du, 2M. Olivo, 3R. Mahendran, 1B.Bay, 1National University of Singpore, Singapore, 2National University of Singapore, Singapore, 3National Cancer Center, Singapore |
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11:45am
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Immune-mediatated Regression
of Tumors after Photodynamic Therapy C. Dees, J. Harkins, T. Scott, E.Wachter, Provectus Pharmaceuticals, Inc., Knoxville, TN |
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| 9:00am-12:00pm Laval |
C5 Contributed Papers Platform
Session Chairs: David Mitchell, University of Texas, Smithville, TX and Donna Kusewitt, The Ohio State University, Columbus, OH |
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9:00am
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UVA-Induced Cyclobutane Pyrimidine
Dimers are Predominantly Formed at Thymine-Thymine Dipyrimidine Sites 1P. Rochette, 1R. Drouin, 1J. Therrien, 1N.Bastien, 2E. Drobetsky, 3E. Sage, 1Hopital Saint-Francois d'Assise, Quebec City, Quebec, Canada, 2Hopital Maisonneuve-Rosemont, Montreal, Quebec, Canada, 3Centre Universitaire, Orsay, France |
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9:15am
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UVA Radiation Enhances Metastasis
of Melanoma Cells: A Mouse Model Study D. Leszczynski, R. Pastila, STUK Radiation and Nuclear Safety Authority, Helsinki, Finland |
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9:30am
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Racial/ethnic Origin, Constitutive
Melanin, and UV-induced DNA Damage 1B. Zmudzka, 2T. Tadokoro, 1H. Bushar, 1S.Miller, 1N. Lao, 2V. Hearing, 1J. Beer, 1FDA, Rockville, MD, 2National Institutes of Health, Bethesda, MD |
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9:45am
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DNA Damage Distribution and
Tumorigenesis is the Xiphophorus Platyfish-Swordtail Melanoma Model D. Mitchell, D. Trono, M. Lowery, R.Nairn, M.D. Anderson Cancer Center, Smithville, TX |
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10:00am
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Protoporphyrin IX accumulation
in Basal Cell Carcinoma and Normal Skin after Topical Application of Methyl
Aminolevulinate (M-ALA) E. Angell-Petersen, K. Giercksky, J. Moan, Q.Peng, A. Soler, H. Steen, R. Sørensen, T. Warloe, The Norwegian Radium Hospital, Oslo, Norway |
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10:15am
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Enhancement of Porphyrin Accumulation
Using ALA Prodrug Peptide Derivatives 1H. Nakanishi, 2L. Rogers, 3I. Eggleston, 2T.Butler, 1S. MacRobert, 1University College, London, UK, 2University of St. Andrews, 3University of Dundee |
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10:30am
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Potential Efficacy of a Delta
5-aminolevulinic Acid Thermosetting Gel Formulation for Using in Photodynamic
Therapy of Lesions of the Gastrointestinal Tract L. BourrT, S. Thibaut, Y. Lajat, T.Patrice, Hopital Laennec, Nantes, France |
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10:45am
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Photonuclease Activity of Naphthalene
Imide and Diimide Derivatives S. McMasters, B. Abraham, V. Szalai, L.Kelly, University of Maryland, Baltimore County, Baltimore, MD |
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11:00am
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Bladder Cancer Detection with
Hypericin Using Macroscopic Fluorescence Cystoscopy and Laser Confocal Microscopy 1M. Olivo, 2W. Lau, 2P. Tan, 1V.Manivasager, 1K. Soo, 2C. Cheng, 1National Cancer Centre, 2Singapore General Hospital, Singapore |
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11:15am
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The Slug Transcription Factor
Mediates Epithelial-Mesenchymal Transformation in Keratinocytes 1D. Kusewitt, 2P. Savagner, 3L. Hudson, 1The Ohio State University, Columbus, OH, 2Centre de Recherche en Cancerologie, Montpellier, France, 3University of New Mexico, Albuquerque, NM |
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11:30am
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Effects of Photodynamic Therapy
with Aluminum Phthalocyanine on Apoptosis Linked Proteins in Hepatic Carcinoma
Cells E. Haseroth, N. Akgün, A. Rück, Institute for Lasertechnologies in Medicine and Metrology, Ulm, Germany |
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11:45am
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High Frequency of UV Type Mutations
at the INK4a-ARF Locus in Squamous Cell Carcinomas from PUVA-treated Psoriasis
Patients H. Kreimer-Erlacher, H. Seidl, B. BSck, L.Cerroni, H. Kerl, P. Wolf, Karl Franzens University, Graz, Austria |
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| 9:00am-12:00pm Bellevue |
D5 Photo-Control in Biological
Systems Chair: Bulent Mutus, University of Windsor, Windsor, Ontario, Canada |
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| This symposium jointly supported in part by Empix Imaging, Varian Canada, Inc., Applied Photopysics | ||
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9:00am
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Introductory Remarks B. Mutus |
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9:05am
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Photo-control of Helix Content
in Peptides 1A. Woolley, 1J. Kumita, 2D. Flint, 2O.Smart, 1University of Toronto, Toronto, ON, 2University of Birmingham, Edgbaston |
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9:35am
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Separation of Spliceosome Assembly
from Catalysis Using Caged Pre-mRNA Substrates A. MacMillan, University of Alberta, Edmonton, Alberta, Canada |
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10:05am
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Isoform Specific Control of
Nitric Oxide Synthase Activity Using a Caged Inhibitor 1G. Guillemette, 1H. Montgomery, 2B. Perdicakis, 1D.Fishlock, 3G. Lajoie, 2E. Jervis, 1University of Waterloo, Waterloo, Ontario, Canada, 2University of Waterloo, Waterloo, Ontario, Canada, 3University of Western Ontario, Ontario, Canada |
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10:35am
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Break | |
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11:00am
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Photocontrol of Liposome-Mediated
Drug Delivery 1P. Shum, 1Z. Zhang, 2J. Kim, 1D.Thompson, 1Purdue University, West Lafayette, IN, 2Janus Biosystems, West Lafayette, IN |
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11:30am
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Photoregulation of S-nitrosothiol
Formation S. Akhter, B. Mutus, University of Windsor, Windsor, Ontario |
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| 12:10pm-1:30pm | Lunch - On Your Own | |
| 1:30pm-2:30pm Salle de Bal |
ASP New Investigator Award Lecture Pinopsin and Pineal Phototransduction
Pathway to the Circadian Oscillator |
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| 2:30pm-5:30pm Frontenac |
A6 UV effects in the Aquatic
Environment Chairs: Patrick Neale, Smithsonian Environmental Research Center, Edgewater, MD and Warwick Vincent, Laval University, Quebec City, Quebec, Canada |
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2:30pm
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UV Effects in the Aquatic
Environment: An Overview P. Neale, Smithsonian Environmental Research Center Edgewater MD |
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2:45pm
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UV Optics of Ice-Covered Ecosystems
in a Changing Climate. W. Vincent, C. Belzile, Laval University, Quebec City, Quebec, Canada |
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3:00pm
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Photochemical Reactivity of
Chromophoric Dissolved Organic Matter in Lakes and the Coastal Atlantic
Ocean 1C. Osburn, 2D. Morris, 2B. Hargreaves, 3R.Coffin, 3T. Boyd, 1National Research Council, Washington DC, 2Lehigh University, Bethlehem PA, 3Naval Research Laboratory, Washington DC |
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3:15pm
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Spatial and Temporal Variation
in Bacterioplankton Response to Ultraviolet Radiation W. Jeffrey, University of West Florida Pensacola FL |
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3:30pm
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Simple Functions Describing
the Effects of UV on Daily Water Column Photosynthesis J. Cullen, R. Davis, Y. Huot, M.Lehmann, Dalhousie University, Halifax Nova Scotia, Canada |
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3:45pm
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Does Exposure to UV Radiation
Affect the Productivity and Fatty Acid Composition of Aquatic Biofilms? 1M. Arts, 2R. Robarts, 3R. Sommaruga, 4J.Frenette, 5A. Quesada, 6T. Zohary, 7P. Bossard, 8K. Huggins, 1National Water Research Institute, Burlington Ontario, 2National Water Research Institute, Saskatoon Saskatchewan, Canada, 3University of Innsbruck, Institute of Zoology and Limnology Innsbruck Austria, 4University of Quebec, Quebec, Canada, 5Universidad Autonoma de Madrid, Madrid Spain, 6Y. Allon Kinneret Limnological Laboratory , Tiberia Israel, 7Limnological Research Centre Kastanienbaum, Switzerland |
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4:00pm
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Temperature Dependent UV Responses
in Zooplankton: Implications of Climate Change 1C. Williamson, 1G. Grad, 1E. MacFadyen, 2H.De Lange, 3D. Mitchell 1Lehigh University, Bethlehem PA, 2Wageningen University, The Netherlands, 3The University of Texas, Smithfield, TX |
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4:15pm
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Photic Control and Physiological
Consequences of Accumulating Mycosporine-like Amino Acids (MAAs) in Corals
and Other Marine Invertebrates 1. Shick, University of Maine, School of Marine Sciences Orono ME |
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4:30pm
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UV-B Effects in Mesocosms :
Minimal Response of Algal Biomass and Growth S. Roy, Institut des Sciences de la Mer de Rimouski, Rimouski Quebec |
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4:45pm
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Mesocosm Studies of UV-B Effects
on the First Level of the Microbial Food Web: A 10-Year Retrospective 1S. Demers, 1C. Nozais, 2B. Mostajir, 3G.Ferreyra, 1S. Roy, 1M. Gosselin, 1J. Chanut, 1E. Pelletier, 1Institut des Sciences de la Mer de Rimouski (ISMER), Rimouski Canada, 2Ecosystemes lagunaires, CNRS, Universite Montpellier II, Montpellier France, 3 |
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5:00pm
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Bio-optical heterogeneity in
a large fluvial lake (Lac Saint-Pierre, Quebec). 1J. Frenette, 2M. Arts, 3B. Daoust, 4J.Morin, 5C. Martin, 101J. Frenette 1Département de Chimie-biologieTrois-Rivières, Quebec, 2 National Water Research InstituteBurlington, Ontario, 3 Service de métérologie, Ste-Foy, Quebec, 101Département de Chimie-biologieTrois-Rivières QC. |
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| 2:30pm-5:30pm Salle de Bal |
B6 Phototoxicity mechanisms:
Cellular and molecular approaches Chairs: Pascale Reinhardt, Health Canada, Ottawa, Ontario, Canada and Donald Forbes, Argus Research, Horsham, PA |
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| This symposium is sponsored by Argus Research | ||
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2:30pm
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New Aspects of Phototoxicity
Mechanisms in Saccharomyces cerevisiae, a Useful Eukaryotic Model
System D. Averbeck, Y. Cohen, M. Dardalhon, Institut Curie-Recherche, Orsay France |
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3:00pm
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Molecular Responses to Drug-Induced
Photo-Genotoxicity: from DNA Damage to Apoptosis. L. Marrot, J. Belaïdi, C. Jones, P.Perez, J. Meunier, Aulnay sous bois, France |
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3:30pm
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In Vitro Studies of Drug Phototoxicity
Using HaCaT Keratinocytes C. Chignell, National Instiutes of Health, Triangle Park, NC |
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4:00pm
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Break | |
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4:15pm
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Measurement of Dimeric Lesions
and Oxidized Bases in Cellular DNA for the Evaluation of Drug Photogenotoxicity J. Cadet, T. Douki, J. Ravanat, S.Sauvaigo, SCIB/LAN & UMR, Grenoble France |
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4:45pm
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New Horizons in Photo-Genotoxicity
Testing. 1S. Brendler-Schwaab, 2L. Müller, 3P. Kasper, 1Bayer AG, Wuppertal, Germany, 2Novartis AG, Basel, Switzerland, 3Federal Institute for Drugs and Medical Devices (BfArM) Bonn Germany |
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5:15pm
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Effects of Topical Application
of Creams Containing Alpha- or Beta-Hydroxy Acids on the Carcinogenesis
of Simulated Solar Light in Male and Female SKH-1 Hairless Mice 1P. Howard, 1B. Miller, 1L. Couch, 1D.Molefe, 1R. Kodell, 2J. Beer, 3 W. Wamer, 1 U.S. Food and Drug Administration, Jefferson, AR, 2 U.S. Food and Drug Administration, Rockville MD, 3U.S. Food and Drug Administration, Washington DC |
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| 2:30pm-5:30pm Laval |
C6 UV-induced cell death Chairs: Girish Shah, Laval University, Quebec City, Quebec, Canada, Douglas Brash, Yale University, New Haven, CT |
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2:30pm
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Signal Transduction by JNK R. Davis, Howard Hughes Medical Institute, Worcester, MA |
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3:00pm
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Jun, JNK, and the Mammalian
UV Response M. Karin, University of California, San Diego, CA |
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3:30pm
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ATF2-Driven Peptide Sensitizes
Melanoma to Apoptosis and Inhibits its Growth and Metastasis Z. Ronai, V. Ivanov, A. Bhoumik, Ruttenberg Cancer Center New York NY |
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4:00pm
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Break | |
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4:15pm
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Inactivating E2F1 Restores
Apoptosis Sensitivity and Cancer Resistance to Trp53-Deficient Mice 1,2N. Wikonkal, 1,2E. Remenyik, 1D. Knezevic, 1W.Zhang, 1M. Liu, 3D. Johnson, 1D. Brash, 1Yale School of Medicine New Haven CT, 2University Medical School of Debrecen Debrecen Hungary, 3M.D. Anderson Cancer Center Smithville TX |
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4:45pm
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Role of Poly(ADP-ribose) Polymerase
in UV-induced Cell Death* 1Shah, Y. Le Rhun, M. Vodenicharov, 4E.Affar, Laval University, Quebec City,Quebec, Canada |
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5:15pm
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Cells Lacking Poly(ADP-ribose)
Polymerase-1 are Resistant to UVB-induced Apoptosis.* M. Vodenicharov, G. Shah, Laval University, Quebec City, Quebec, Canada |
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| 2:30pm-5:30pm Bellevue |
D6 Molecular Sensors in Photobiology Chair: David Lawrence, The Johns Hopkins University Applied Physics Laboratory, Baltimore, MD |
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2:30pm
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Introductory Remarks | |
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2:35pm
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Crystalline Colloidal Self
Assembly: A Motif for Fabricating Smart Materials and Chemical Sensing Devices. S. Asher, University of Pittsburgh, Pittsburgh, PA |
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3:05pm
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Multi-Sensory Fiber Optic Probes
for PDT Dosimetry: Construction, Performance and Error Analysis L. Lilge, N. Pomerleau, University of Toronto, Toronto Ontario, Canada |
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3:35pm
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De Novo Designed Electron Transfer
Proteins G. McLendon, M. Case, Princeton University, Princeton, NJ |
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4:05pm
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Break | |
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4:30pm
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Cortisol/DHEA Sensors for Stress
Measurement in Soldiers J. Sample, D. Lawrence, Johns Hopkins University Applied Physics Laboratory Laurel MD |
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5:00pm
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Fluorescence-Based Biosensors
of Metal Ions at Low Concentrations in vitro R. Thompson, University of Maryland, Baltimore Baltimore MD |
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| 5:30pm-7:00pm Place D'Armes/ Jacques Cartier |
Poster Session II and Exhibits | |
| Photosynthesis, Bio- & Chemiluminescence | ||
| Transition-state Inhibitors
of Coelenterazine Bioluminescence: Probing the Chiral Enviroment of Active
Site in Renilla Luciferase 1C. Wu, 1H. Nakamura, 2A. Murai, 3S.Inouye, 1Nagoya University, Nagoya, Japan, 2Hokkaido University, Sapporo, Japan, 3Yokohama Research Center, Yokohama, Japan |
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| Cloning and Expression
of cDNA for the Luciferase from the Marine Ostracod Cypridina noctiluca 1K. Kobayashi, 2Y. Nakajima, 3H. Kubota, 1,2Y.Ohmiya, 1University of Shizuoka, Shizuoka, 2National Institute of AIST, Ikeda, Osaka, 3ATTO Corp., Bunkyo, Tokyo |
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| Chloroplast Movement
Significantly Alters Light Distribution but has Little Effect on Photosynthesis
in Leaves of Alocasia 1W. Williams, 1H. Gorton, 2T. Vogelmann, 1A.Merritt, 1Saint Mary's College of Maryland, MD, 2University of Vermont, Burlington, VT |
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| Sequences and Structures
of Luciferases from Different Dinoflagellate Species L. Liu, J. Hastings, Harvard University, Cambridge, MA |
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| Photochemistry and Photophysics | ||
| Effects of Benzo and
Naphtho Substitution on Spectroscopic Properties of meso -Tetraphenylmetalloporphyrins 1J. Rogers, 1W. Su, 2S. Vinogradov, 2P.Fleitz, 1D. McLean, 1Air Force Research Laboratory, WPAFB, OH, 2University of Pennsylvania, Philadelphia, PA |
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| A Spectroscopic Investigation
of the Singlet and Triplet States of Synthetic Chlorins H. Frank, R. Ilagan, Z. Pendon, J.McCarthy, C. Brückner, University of Connecticut, Storrs, CT |
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| Degradation of Alginate
by Photosensitized Riboflavin S. Baldursdottir, H. Tonnesen, J. Karlsen, University of Oslo, Oslo, Norway |
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| A Photochemical Study
of Keratinocytes Loaded with 2'7'-dichlorofluorescin: Implications for the
Detection of Reactive Oxygen Species Generated by UVA Irradiation C. Chignell, R. Sik, NIEHS, NIH, Research Triangle Park, NC |
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| Singlet Oxygen Does
Not Oxidize 2'7'-dichlorofluorescin to the Fluorescent 2'7'-dichlorofluorescein P. Bilski, A. Belanger, C. Chignell, NIEHS/NIH, Research Triangle Park, NC |
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| Development of Novel
Photocrosslinked Poly(ethylene glycol) Hydrogels R. Leblanc, Y. Zheng, University of Miami, Coral Gables, FL |
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| Synthesis of Alcohols
Derived from Chlorophyll a. Regioselectivity in the Reduction of
Carbonyl Functions with Hydrides 1,2D. Berezin, 3R. Bonnett, 1E. Achraf El Merouani, 1Josep R. Garabatos, 1A.Virginia Pérez, 1Francesc Pont, 1,4F. Postigo, 1,3A. Salgado, 1N. Tovar, 1M. Vallés, 1University of Barcelona, Barcelona, Spain, 2Ivanovo State University of Chemistry and Technology (ISUCT), Ivanovo, Russia, 3University of London, London, UK, 4University of Barcelona, Barcelona, Spain |
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| Substitution Effect
on the Promazine Photophysical Properties C. Garcia, R. Oyola, L. Piñero, R.Arce, University of Puerto Rico, Humacao, PR |
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| Menadione Photosensitized
Oxidation of DNA F. Bergeron, D. Hunting, R. Wagner, Universite de Sherbrooke, Sherbrooke, Quebec, Canada |
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| Novel Amphiphilic Photosensitizers:
Their Synthesis and Properties W. Sharman, J. van Lier, Universite de Sherbrooke, Sherbrooke, Quebec, Canada |
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| Photosensory & Circadian Biology | ||
| Photosensitized Structural
Modifications in [:agr:]-crystallin. Are They Always Impairing the Chaperone-like
Activity of [:agr:]-crystallin? 1A. Sgarbossa, 1,2T. Youssef, 1F. Lenci, 1CNR Istituto BioFisica, Pisa, Italy, 2RIO Res. Inst. Ophthalmology, Giza, Egypt |
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| Effect of Pupil Constriction
on Monochromatic Light Induced Melatonin Suppression in Humans 1G. Glickman, 1J. Hanifin, 1R. Fucci, 1,2M.Rollag, 1E. Gerner, 1B. Byrne, 1G. Brainard, 1Thomas Jefferson University, Philadelphia, PA, 2University of Health Sciences, Bethesda, MD |
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| 460 nm vs. 555 nm
Monochromatic Light in the Suppression of Melatonin in Healthy Humans: A
Within-subjects Design 1S. Jasser, 1J. Gardner, 1J. Hanifin, 1G.Glickman, 1B. Byrne, 2M. Rollag, 1G. Brainard, 1Thomas Jefferson University, Philadelphia, PA, 2University of Health Sciences, Bethesda, MD |
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| Mammalian Clocks
Reset Daily by Dawn and Dusk Zeitgebers H. Kern, Inter-Tech, Bethlehem, PA |
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| Optical dosimetry, Imaging | ||
| Spectrally-Resolved Confocal
Microscopy Studies of the Emission Properties of Individual Human Ocular
Lipofuscin Granules 1N. Haralampus-Grynaviski, 1L. Lamb, 1J. Simon, 2T.Sarna, 1Duke University, Durham, NC, 2Jagiellonian University, Krakow Poland |
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| A Custom Laser Scanning
Confocal Fluorescence Microscope with Simultaneous Multi-wavelength Imaging,
Spectroscopy and Anisotropy Capabilities C. Bigelow, D. Conover, T. Foster, University of Rochester, Rochester, NY |
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| Prediction of Sun Protection
Factors by Calculation of Transmissions with a Calibrated Step Film Model B. Herzog, Ciba Specialty Chemicals, Inc., Grenzach-Wyhlen, Germany |
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| Variations in the Spatial
Origin of Detected Fluorescence in Tissue due to Fiberoptic Probe Geometry T. Pfefer, M. Ediger, FDA, Rockville, Maryland |
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| Confocal Fluorescence
Imaging During Irradiation of Photosensitized Spheroids Enables Tests of
Photobleaching Mechanisms S.Mitra, C. Bigelow, T. Foster, University of Rochester, Rochester, NY |
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| PDT Light Sources Output
Assessment 1M. Bucking, 1E. Dickson, 2F. fischer, 1R.Pottier, 1The Royal Military College of Canada, Kingston, Ontario, Canada, 2Beirsdorf AG, Hamburg, Germany |
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| Spectral Bandwidth Used
to Determine UV Action Spectra E. Chaney, D. Sliney, USACHPPM Aberdeen Proving Ground, MD |
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| Photomedicine | ||
| Action Spectra for the
Photoconsumption of Oxygen by Human Ocular Lipofuscin, Lipofuscin Extracts,
and A2E 1A. Pawlak, 1M. Rozanowska, 1M. Zareba, 1T.Sarna, 2L. Lamb, 2J. Simon, 1Jagiellonian University, Krakow, Poland, 2Duke University, Durham, NC |
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| Variables associated
with the development of pigmentation in human skin S. Miller, B. Zmudzka, N. Lao, S.Coelho, J. Beer, Food and Drug Administration, Rockville, MD |
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| Measurement of Biophysical
Changes in Human Skin Caused by Ultraviolet Light Exposure I. Sadiq, T. Stoudemayer, A. Kligman, S.K.I.N., Inc., Conshohocken, PA |
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| Interleukins
IL-1and IL-6 Release in Human Keratinocytes Exposed to Ultraviolet Radiation P. Reinhardt, Y. Deslauriers, M. Cybulski, Consumer and Clinical Radiation Protection Bureau, Ottawa, Ontario, Canada |
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| Comparison Between the
UV-light of 311 nm Induced Down-regulation of 12(S)-hydroxyeicosatetraenoic
Acid Receptors in Normal Skin Keratinocytes and Keratinocytes from Vaginal
Mucosa 1P. Arenberger, 1I. Obstova, 2I. Kraus, 1B.Havlickova, 1E. Matouskova, 1Charles University School of Medicine, Prague, Czech Republic, 2Charles University School of Medicine, Prague, Czech Republic, 3Czech Academy of Sciences, Prague, Czech Republic |
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| Low Power Light Effects
on Cells 1R. Lavi, 2A. Shainberg, 1H. Fridmann, 2M.Sinyakov, 2H. Britbart, 1,3R. Lubart, 1Bar-Ilan University, Ramat-Gan, Israel, 2Bar-Ilan University, Ramat-Gan, Israel, 3Bar-Ilan University, Ramat-Gan, Israel |
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| DNA Damage and Repair | ||
| Human Cells Expressing the
Hepatitis B-virus X Protein are Deficient in Both Global - and Transcription
- Coupled Nucleotide Excision Repair of UV-induced DNA Damage 1G. Mathonnet, 1J. Therrien, 2M. Alaoui-Jamali, 1E.Drobetsky, 1University of Montreal, Quebec, Canada, 2McGill University, Montreal, Quebec, Canada |
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| Abrogation of p53 Unmasks
an S-phase Arrest Following Ultraviolet Radiation 1J. Spronck, 1,2,3B. McKay, 1Ottawa Regional Cancer Center, Ottawa, Ontario, Canada, 2Ottawa Regional Cancer Center, Ottawa, Ontario, Canada, 3University of Ottawa, Ottawa, Ontario, Canada |
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| An Oxoguanine Glycosylase
Knockout Mutant in Arabidopsis T. Murphy, Plant Biology, Davis, CA |
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| Deamination Kinetics of Cytosine
and 5-methylcytosine-Containing Photoproducts in Single and Double Strand
Oligodeoxynucleotides Y. Wang, M. Vairamani, M. Gross, J.Taylor, 1Washington University, St. Louis, MO |
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| UVB-induced Impairment of
Specific Cellular Immune Responses After Hepatitis B Vaccination of Humans
Correlates to Epidermal cis-urocanic Acid Levels 1A. Sleijffers, 2A. Kammeyer, 3F. De Gruijl, 4G.Boland, 5W. Van Vloten, 1H. Van Loveren, 1J. Garssen, 2M. Teunissen, 1National Institute of Public Health and the Environment, Bilthoven, The Netherlands, 2University of Amsterdam, Amsterdam, The Netherlands, 3Leiden University Medical Center, Leiden, The Netherlands, 4University Medical Center, Utrecht, The Netherlands, 5University Medical Center, Utrecht, The Netherlands |
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| UVB Radiation Induces Upregulation
of Calcitonin Gene-related Peptide (CGRP) Levels in Human Filter Skin Samples A. Sleijffers, M. Herreilers, H. Van Loveren, J.Garssen, National Institute of Public Health and the Environment, Bilthoven, The Netherlands |
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| Histological Evaluation of
the UVA-induced Metastatic Lung Melanomas in Mice: A Pilot Study R. Pastila, D. Leszczynski, STUK- Radiation and Nuclear Safety Authority, Helsinki, Finland |
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| Proteins From Rat Liver Nuclear
Extracts which Recognize DNA Damaged by UV and Chemical Carcinogens M. Pietrowska, P. Widlak, J. Rzeszowska-Wolny, Center of Oncology, Gliwice, Poland |
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| Decreased Expression of p48
DDB2 and XPC Cannot Account for the Increased Sensitivity of
p53-deficient Fibroblasts to UV- and Cisplatin-induced Apoptosis 1C. Becerril, 1J. Spronck, 1,2,3B. McKay, 1Ottawa Regional Cancer Center, Ottawa, Ontario, Canada, 2University of Ottawa, Ontario, Canada, 3University of Ottawa, Ontario, Canada |
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| Photodynamic Therapy 2 | ||
| Hypericin Effects on Aqueous
Humor and Rhodopsin of Rabbits' Eye 1F. El Refaei, M. Ibrahim, 1S. Ahmed, 1H.Taha, 1Research Institute of Ophthalmology, Egypt |
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| Treatment of Neoplasms by
Synchrotron Radiation and Mono-L-aspartyl Aurochlorin e6 1T. Tsuchida, 2K. Aizawa, 1T. Ishizumi, 1T.Okunaka, 1H. Shimatani, 3K. Kinoshita, 1H. Kato, 1Tokyo Medical University, Tokyo, Japan, 2Tokyo Medical University, Tokyo, Japan, 3Funabashi City Medical Center, Funabashi, Japan |
||
| Irradiance-Dependent Photobleaching
and Photoproduct Accumulation during Photofrin-, mTHPC- and ALA-PDT in vivo:
A Comparative Study J. Finlay, S. Mitra, T. Foster, University of Rochester Rochester NY |
||
| Evaluation of Brominated
Porphyrin Sensitizer for Photodynamic Therapy T. Patrice, L.Bourré, S. Thibaut, Y.Lajat, Hopital Laennec, Nantes France |
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| Photocytotoxicity, Cellular
Internalization and Metabolization of -Mannosylporphyrins in Retinoblastoma
Cells 1I. Laville, 1J. Blais, 2P. Maillard, 2B.Loock, 2D. Grierson, 3J. Blais, 2D. Carrez, 2A. Croisy, 1Laboratoire de Physicochimie BiomolTculaire et Cellulaire Paris France, 2CNRS UMR 176 et INSERM U350 Orsay France, 3LCSOB, Paris France, 101LPBC Paris France |
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| Photodynamic Activities of
Amphiphilic Trisulfonated Phthalocyanines Substituted with Alkynyl Side-chains. Cauchon, H. Tian, J. van Lier, Universite de Sherbrooke, QC, Canada |
||
| Sensitivity of Photodynamic
Therapy Resistant Human Colon Carcinoma HT29 Cells to UV and Cisplatin 1N. Zacal, 2,3H. Wang, 2,3G. Singh, 1A.Rainbow 1McMaster University, Hamilton, Ontario, Canada, McMaster University, Hamilton, Ontario, 3Hamilton Regional Cancer Centre Hamilton, Ontario, Canada |
||
| Spectral Characteristics
and Clinical Application of Mono-L-Asparatyl Aurochlorin e6 (Au-NPe6) T. Ishizumi, T. Tsuchida, K. Aizawa, T.Okunaka, H. Kato, Tokyo Medical University, Tokyo Japan |
||
| Enhancement of Epidermal
Growth Factor Receptor Targeted Treatment of Ovarian Cancer with Photodynamic
Therapy 1I. Rizvi, 1,2M. del Carmen, 1A. Moor, 1,2T.Dinh, 1T. Hasan, 1Wellman Laboratories of PhotomedicineBoston, MA, 2The Vincent Memorial Gynecologic Oncology Division, Boston, MA |
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| Targeted Photoimmunotherapy
of Epidermal Growth Factor Receptor: Mechanistic Parameters Governing Phototoxic
Efficiency I. Rizvi, W. Rice, D. Sharlin, T.Dinh, W. Yu, T. Hasan, Wellman Laboratories of Photomedicine, Boston, MA |
||
| Macro-micro Fluorescence
Imaging of Bladder Tumour Xenografts on Nude Mice Using 5-aminolevulinic
Acid and its Esterified Analogue Aminolevulinic Acid Methyl Ester 1V. Manivasager, 2P. Heng, 2H. Jinsong, 2Z.Wei, 1S. Khee Chee, 1M. Olivo 1National Cancer Center, Singapore, Singapore, 2National Cancer Centre Singapore, Singapore |
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| 5:30pm-6:30pm Laval |
Grantsmanship Lecture Strategies for Winning an NIH
Grant |
|
| 7:00pm-7:30pm Vercheres |
Reception | |
| 7:30pm-10:30pm Salle de Bal |
Banquet | |
