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30th Annual Meeting of the American Society for Photobiology
Fairmont Le Chateau Frontenac
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| MONDAY, JULY 15 | ||
| 7:00-9:00am Place D'Armes/ Jacques Cartier |
Continental Breakfast/Exhibits/Poster Viewing I | |
| 8:00-9:00am Salle de Bal |
Photobiology School Lecture 2 The Determination of Immune Protection
Factors of Sunscreens |
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| 9:00-12:00pm Frontenac |
A3 Photoimmunology Chairs: Paul Bergestrasser, UT Southwestern Medical Center, Dallas, TX and, Margaret Kripke, UT M.D.Anderson Cancer Center, Houston, TX |
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9:00am
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Photoimmunology--Where have
we been? Where are we going? M. Kripke, Department of Immunology, M. D. Anderson Cancer Center, Houston, TX |
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9:15am
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Photoimmunology in Quebec City:
Where are we Going Today? P. Bergestrasser, UT Southwest Medical Center, Dallas, TX |
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9:30am
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Comparing the Effects of T4
liposomes, RNA fragments, and Photoprotective Lotion on UV-induced Immune
Suppression in Human Subjects. 1,2E. Baron, 1F. Swain, 3M. Matsui, 3T.Mammone, 3K. Marenus, 3D. Maes, 1K. Cooper, 1,2S. Stevens, 1Case Western Reserve, Cleveland, OH, 2D Louis Stokes Veterns Affairs Medical Center, Cleveland, OH, 3Estee Lauder Companies, Melville, NY |
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10:00am
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An Integral Role of CD80/CD86-CD152
Co-stimulation in Murine Photocarcinogenesis 1S. Beissert, 2J. Bluestone, 3A. Sharpe, 1T.Schwarz, 1A. Scherer, 1University of Muenster, Muenster, Germany, 2UCSF, San Francisco, CA, 3HarvardUniversity, Boston, MA |
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10:15am
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Cis-urocanic Acid Acts as a
5-HT Receptor Agonist 1Walterscheid, D. Nghiem, S. Ullrich, M.D. Anderson Cancer Center, Houston, TX |
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10:30am
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Cis-urocanic Acid Causes Immunosuppression
Through 5-HT Receptor Signaling D. Nghiem, J. Walterscheid, S. Ullrich, M.D. Anderson Cancer Center, Houston, TX |
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10:45am
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Immune Function in the Hepatocyte
Growth Factor/Scatter Factor (HGF/SF) Transgenic Mouse Model of Ultraviolet
(UV) Irradiation-induced Melanoma 1,3H. Poetschke Klug, 2F. Noonan, 3G. Merlino, 1National Cancer Institute, Bethesda MD, 2George Washington University Medical Center, Washington, D.C., 3National Cancer Institute, Bethesda, MD |
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11:00am
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UV Fingerprint and Oxygen Radical
Mediated Genetic Damage Occur at Different Depths in the p53 Gene of Solar
Keratosis and Squamous Cell Carcinoma of the Skin in Humans 1N. Agar, 1G. Halliday, 1R. Barnetson, 3M.Wheeler, 2A. Jones, 1University of Sydney, Sydney, NSW, 2Royal Prince Alfred Hospital, Sydney, NSW, 3Westmead Hospital, Sydney, NSW |
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11:15am
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Telomerase Reactivation and
p53 Mutation in Solar Keratosis 1,2A. Jones, 1,2N. Agar, 1,2A. Nikolic, 1,2R.Barnetson, 1,2G. Halliday, 1University of Sydney, Sydney, NSW, 2Royal Prince Alfred Hospital, Sydney, NSW |
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11:30am
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Influence of Adaptation to UVB
on UVB-induced Immunosuppression 1,2A. Sleijffers, 1J. Garssen, 3F. De Gruijl, 4G.Boland, 4J. Van Hattum, 1H. Van Loveren, 1National Institute of Public Health and the Environment, Bilthoven, The Netherlands, 2University Medical Center, Utrecht, The Netherlands, 3Leiden University Medical Center, The Netherlands, 4University Medical Center, Utrecht, The Netherlands |
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11:45am
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UV pre-exposure Increaseses
the Severity of Buruli Ulcer Disease (BUD) 1R. Cope, 1J. Hartman, 1C. Morrow, 1W.Haschek, 2P. Small, 1University of Illinois, Urbana, IL, 2Walters Life Sciences, Knoxville, TN |
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| 9:00am-12:00pm Salle de Bal |
B3 PDT: Oxidative Interactions Chairs: Albert Girotti, Medical College of Wisconsin, Milwaukee, WI and Giulio Jori, University of Padova, Padova, Italy |
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9:00am
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Photosensitized Lipid Peroxidation
and Apoptotic Killing in 5-aminolevulinate-treated COH-BR1 Cells: Protective
Effects of Mitochondrial GPX4 Overexpression 1A. Girotti, 1T. Kriska, 1,2W. Korytowski, 1Medical College of Wisconsin, Milwaukee, WI, 2Jagiellonian University, Krakow, Poland |
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9:25am
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Photodynamic Properties of a
Series of Zinc Tetrasubstituted Phthalocyanines S. Brown, University of Leeds |
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9:50am
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Phthalocyanines as Phototherapeutic
Agents for the Treatment of Microbial Infections G. Jori, Department of Biology, University of Padova, Padova, Italy |
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10:15am
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Break | |
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10:40am
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Dendritic Cells and PDT 1Hunt, S. Wang, D. King, H.Jiang, R. Salmon, QLT, Inc., Vancouver, B.C. |
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11:05am
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Monitoring Real-time Tumor Response
in the Rat During PDT Using Positron Emission Tomography van Lier, R. Lecomte, M. Bentourkia, University of Sherbrooke, Quebec City, Quebec, Canada |
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11:30am
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Analysis of Cellular Respiration
Changes In the RIF-1 Tumor in response to Photodynamic Therapy with Verteporfin 1X. Zhou, 1B. Pogue, 2J. O'Hara, 2C.Wilmot, 2H. Swartz, 1Dartmouth College, Hanover, NH, 2Department Medical School, Hanover, NH |
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11:45am
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Photodynamic Therapy with Toluidine
Blue in K562 Leukemic Cells S. Dussault, G. Viau, R. Bissonnette, Hopital Notre-Dame, Montreal, Quebec, Canada |
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| 9:00am-12:00pm Laval |
C3 DNA Repair: Cellular Signaling
and Tumour Suppressors Chairs: Elliott Drobetsky, University of Montreal, Montreal, Quebec, Canada and Alain Sarasin, CNRF, Villejuif, France |
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9:00am
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Activation of Some Signaling
Pathways in Skin Tumours from DNA Repair Deficient Xeroderma Pigmentosum
Patients 1A. Sarasin, 1L.ljhn Day-a-Grosjean, 1S. Queille, 2N.Soufir, 2N. Basset-Seguin, 1J. Ehrhart, 1Laboratory of Genetic Instability and Cancer, Villejuif, France, 2Hopital Saint-Louis, Paris, France |
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9:25am
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Modulation of the DNA Damage
Response in UV-exposed Human Cells Through Genetic- vs. Functional-inactivation
of the p53 Tumor Suppressor 1E. Drobetsky, 1C. Leger, 1G. Mathonnet, 1J.Therrien, 2R. Drouin, 3M. Alaoui-Jamali, 1University of Montreal, Montreal, Quebec, Canada, 2Laval University, Quebec City, Quebec, Canada, 3McGill University, Montreal, Quebec, Canada |
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9:50am
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Recombination Functions of BRCA1 R. Scully, N. Puget, I. Shim, 1Beth Israel Deaconess Medical Center, Boston, MA |
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10:15am
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Break | |
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10:45am
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Mechanism of p53 and BRCA1 Tumor
Suppressor Genes in Regulating Nucleotide Excision Repair J. Ford, S. Adimoolam, M. Fitch-Bruhns, A.Hartman, Stanford University School of Medicine and Genetics, Stanford, CA |
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11:10am
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P53 and ING1: Enhancing the
Repair of UV-damaged DNA to Suppress Skin Cancer Development G. Li, K. Cheung, University of British Columbia, Vancouver, BC |
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11:35am
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The Role of a Yeast Homologue
of the Human Phosphatase Activator hPTPA in the Cellular Response to Oxidative
DNA Damage 1J. David, 1X. Yang, 1D. Ramotar, 2L.Gaudreau, 1Universite de Montreal, Montreal, Quebec, Canada, 2University of Sherbrooke, Sherbrooke, Quebec, Canada |
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| 9:00am-12:00pm Bellevue |
D3 Contributed Papers Platform
Session Chairs: Rebecca Goyan, Royal Military College of Canada, Toronto, Ontario, Canada and John Simon, Duke University, Durham, NC |
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9:00am
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Inter-domain Crosstalks within
the Phytochrome A Protein: Functional Implications 1P. Song, 2J. Kim, 1G. Choi, 1C.Park, 1University of Nebraska - Lincoln, Kwangju, Korea, 2University of Nebraska - Lincoln, Lincoln, NE |
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9:15am
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Chloroplast Movement in Alocasia
Does Not Shorten Gas Diffusion Pathlength as Measured by Photoacoustics 1T. Vogelmann, 2H. Gorton, 3S. Herbert, 1University of Vermont, Burlington, VT, 2St. Mary's College of Maryland, MD, 3University of Wyoming, Laramie, WY |
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9:30am
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Atomic Force Microscopy Studies
of the Structural Morphology of Sepia Eumelanin Y. Liu, C. Clancy, J. Simon, Duke University, Durham, NC |
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9:45am
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Subcellular Photodynamics of
Porphyrins Using Two-photon Excitation 1R. Goyan, 2D. Cramb, 2K. Samkoe, 2J.Bogle, 1R. Watering, 1R. Pottier, 1E. Gudgin Dickson, 1Royal Military College of Canada, Kingston, Ontario, Canada, 2University of Calgary, Calgary, Alberta, Canada |
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10:00am
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Structural Requirements for
Efficient Cellular Photoprotection by Carotenoid Derivatives. 1,2J. Kanofsky, 1P. Sima, 1Edward Hines, Jr. VA Hospital, Hines, IL |
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10:15am
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Triplet vs. Singlet and Energy-Transfer
vs. Charge-Transfer Interactions of Metallo-Phthalocyanines with (Hydro)Peroxides T. Gantchev, J. Van Lier, University of Sherbrooke, Quebec, Canada |
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10:30am
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Role of Secondary ROS in Transducing
Membrane Photosensitization to Nuclear Damage G. Ouedraogo, R. Redmond, H. Lilber, Massachusetts General Hospital, Boston, MA |
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10:45am
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Photodegradation Rates of Bacteriorhodopsin D. Sammeth, J. McIntyre, New Mexico Highlands University, Las Vegas, NM |
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11:00am
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Targeted Photodynamic Therapy
for Staphylococcus aureus Soft Tissue Infections in vivo Monitored
by Bioluminescence Imaging 1,2M. Hamblin, 1,2T. Zahra, 3K. Francis, 1,2T.Hasan, 1Massachusetts General Hospital, Boston, MA, 2Harvard Medical School, Boston, MA, 3Xenogen Corporation, Alameda, CA |
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11:15am
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Primary Photophysics Following
UV-A Photoexcitation of Pheomelanin J. Simon, T. Ye, Duke University, Durham, NC |
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11:30am
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Writing on the Genome - Focused
Induction of UV Photoproducts in Cell nuclear DNA by Three-Photon Infra-red
Laser Radiation. 1R. Meldrum, 2S. Botchway, 2G. Hirst, 1University of Birmingham, Birmingham, UK, 2Rutherford Appleton Laboratory, Oxfordshire, UK |
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11:45am
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Interaction of Plasmenylcholine
with Singlet Oxygen and Free Radicals 1J. Kalinowska-Tluscik, 1,2M. Norek, 2D. Thompson, 1T.Sarna, 1Jagiellonian University, Krakow, Poland, 2Purdue University, W. Lafayette, IN |
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| 12:00-1:30pm Le Champlain, Library Room |
Past President's Lunch | |
| 1:30-2:30pm Salle de Bal |
ASP Presidential Lecture Microbial Rhodopsins: Genome-mining
and Structure/Function Relationships in Transport and Signal Transduction |
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| 2:30-5:30pm Frontenac |
A4 Contributed
Papers Platform Session Chairs: Joseph Zuclich, Northrop Grumman Information Technology, San Antonio, TX and Holly Gorton, St. Mary's College of Maryland, St. Mary's, MD |
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2:30pm
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Varying Levels of Dietary Vitamins
E and C Does Not Ameliorate - Carotene Exacerbation of UV-carcinogenesis H. Black, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX |
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2:45pm
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Effects of Solar Radiation
on Photosynthesis in Macroalgae D. Häder, M. Lebert, Friedrich-Alexander Universitat Staudtstr, Erlangen, Germany |
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3:00pm
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UV Radiation and the Snow Alga
Chlamydomonas nivalis 1H. Gorton, 2T. Vogelmann, 1St. Mary's College of Maryland, MD, 2University of Vermont, Burlington, VT |
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3:15 PM
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Visual Significance of Yellow
Optical Filters S. Zigman, Boston University School of Medicine, Woods Hole, MA |
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3:30pm
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Near-UV/Blue Light - induced
Fluorescence in the Human Lens: Potential Veiling Glare Interference with
Visual Function. J. Zuclich, F. Previc, B. Novar, P.Edsall, Northrop Grumman, San Antonio, TX |
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3:45pm
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UV Visible Radiation Hazards
To Lens And Aqueous Humour Protein of the Rabbits' Eye F. El Refaei, Cairo, Egypt |
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4:00pm
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Childhood UV Doses: Reality
versus Myth 1D. Godar, 2F. Urbach, 3F. Gasparro, 4J.van der Leun, 1US Food and Drug Administration, Rockville, MD, 2Temple University School of Medicine, Philadelphia, PA, 3Thomas Jefferson University, Philadelphia, PA, 4Ecofys Utrecht, The Netherlands |
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4:15pm
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Does an Environmental PCB/PCDF
Mixture Enhance Ultraviolet Radiation-Induced Skin Cancer? C. Morrow, K. Imsilp, L. Hanse, University of Illinois, Urbana, IL |
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4:30pm
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Monitoring Tissue Oxygenation
and Viability by Non-invasive Spectrally Resolved Reflectance Imaging as
Applied to Chlorin e6-based Photodynamic Therapy 1,2S. Kimel, 2G. Kostenich, 2A. Orenstein, 1Technion-Israel Institute of Technology, Haifa, Israel, 2Sheba Medical Center, Tel Hashomer, Israel |
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4:45pm
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Photodynamic Therapy with Verteporfin
Increases Tumor pO2 and Enhances the Effect of Radiation Therapy in the
RIF-1 Tumor 1B. Pogue, 2J. O'Hara, 1X. Zhou, 2C.Wilmot, 2H. Swartz, 1Dartmouth College, Hanover, NH, 2Dartmouth Medical School, Hanover, NH |
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5:00pm
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Mycosporine Like Amino Acids
as Potential Cosmetic UV Agents? K. Berg, Roche Vitamins, Ltd., Basel, Switzerland |
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5:15pm
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Effects of Combined PDT and
Ionising Radiation or Hyperthermia on Human Glioma Spheroids 1,2H. Hirschberg, 2,3S. Madsen, 2B. Thromberg, 1Rikshospitalet, Oslo, Norway, 2University of California, Irvine, CA, 3University of Nevada, Las Vegas, NV |
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| 2:30pm-5:30pm Salle de Bal |
B4 ALA-mediated PDT Chairs: Roy Pottier, Royal Military College of Canada, Kingston, Ontario, Canada and Johan Moan, Norwegian Radium Hospital, Oslo, Norway |
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| This syposium is sponsored in part by DUSA Pharmaceuticals, Inc. | ||
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2:30pm
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In vivo Generation of PpIX from
ALA and ALA Derivatives J. Moan, P. Juzenas, A. Juzeniene, S. Stakland, L. Ma, V. Iani, The Norwegian Radium Hospital, Oslo, Norway |
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3:00pm
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Regulation of Porphyrin Synthesis
and the Roles of Cytosolic and Nuclear Porphobilinogen Deaminase (PBGD). Z. Malik, L. Greenbaum, Y. Gozlan, D.Schwartz, D. Katcoff, Bar Ilan University, Ramat Gan, Israel |
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3:30pm
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Current Status of DUSA's Development
of Photodynamic Therapy (PDT) Using Levulan (aminolevulinic acid HCl) S. Marcus, DUSA Pharmaceuticals, Inc., Valhalla, NY |
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4:00pm
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BREAK | |
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4:15pm
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Dermatologic Applications of
PDT A. Oseroff, Roswell Park Cancer Institute, Buffalo, NY |
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4:45pm
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The in vivo Monitoring
of ALA-induced Fluorescence R. Pottier, The Royal Military College of Canada, Kingston, Ontario, Canada |
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5:15pm
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Photodynamic Therapy with both
Topical or Systemic Aminolevulinic Acid Delays the Appearance of UV-induced
Squamous Cell Carcinoma in Hairless Mice Y. Liu, G. Viau, R. Bissonnette, University of Montreal, Montreal, Quebec |
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| 2:30pm- 5:30pm Laval |
C4 DNA Repair Enzymology Chairs: Darel Hunting and Eric Moon-Shong Tang, M.D. Anderson Cancer Center, Smithville, TX |
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2:30pm
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Base Excision Repair of Oxidative
DNA Damage in Mammalian Cells: The Early Steps S. Boiteux, Fontenay aux Roses, France |
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3:00pm
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An Interesting Region within
the Putative Nuclease Domain of E. coli Endonuclease V 1Y. Kow, 2M. Hashimoto, 1B. Imhoff, 3L.Bazaar, 1Emory University, Atlanta, GA, 2NYU Medical School, Tuxedo, NY, 3Trevigen, Inc., Gaithersburg, MD |
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3:30pm
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Transcription-coupled DNA Repair
is Genomic Context Dependent 1Z. Feng, 1W. Hu, 1E. Komissarova, 2A.Pao, 2M. Hung, 2G. Adair, 1M. Tang, 1New York University School of Medicine, Tuxedo, NY, 2University of Texas M.D. Anderson Cancer Center, Smithville, Texas |
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4:00pm
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Break | |
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4:30pm
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Transcription-coupled and Global
Genome Repair Differentially Influence Ultraviolet-B Induced Acute Skin
Effects, Langerhans Cell Migration, Local and Systemic Immunosuppression 1J. Garssen, 2W. Igen, 1H. Van Steeg, 3B.Van Der Horst, 1H. Van Loveren, 1H. Van Kranen, 4F. De Gruijl, 3J. Hoeijmakers, 1National Institute of Public Health and the Environment, Bilthoven, The Netherlands, 2University Medical Center, Utrecht, The Netherlands, 3Erasmus University, Rotterdam, The Netherlands, 4Leiden University Medical Center, Leiden, The Netherlands |
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4:45pm
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Efficient Repair of UV-induced
DNA Damage in Terminally Differentiated Human Keratinocytes 1,2D. Oh, 2K. Yeh, 1University of California - San Francisco, San Francisco, CA, 2VA Medical Center, San Francisco, CA |
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5:00pm
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DNA Repair and Signal Transduction D. Yarosh, AGI Dermatics, Freeport, NY |
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| 2:30pm-5:30pm Bellevue |
D4 Blue Light Receptors in
Plants and Bacteria Chairs: Goldgang Gartner, Max-Planck-Inst. For Radiation Chemistry, Mulheim, Germany |
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2:30pm
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Cryptochromes - Not Cryptic
Any Longer A. Batschauer, O. Kleiner, M. Mueller, O.Panajotow, Phillips University, Marburg, Germany |
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3:00pm
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Phototropins: Light-driven Molecular
Switches in Plants 1R. Bogomolni, 2T. Swartz, 1S. Corchnoy, 1P.Wenzel, 2J. Christie, 2W. Briggs, 1University of California, Santa Cruz, CA, 2Carnegie Institution of Washington, Stanford, CA |
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3:30pm
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Phototropin Function in Fern
and Arabidopsis M. Wada, Tokyo Metropolitan University, Tokyo, Japan |
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4:00pm
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Break | |
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4:30pm
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Photophysics, Photochemistry
and Structural Modeling of Phototropin-related Prokaryotic Proteins: A New
Family of Bacterial Blue-light Receptors A. Losi, Max-Planck Institut for Strahlenchemie, Mnlheim an der Ruhr, Germany and Instituto Nazionale per la Fisica della Materia, Parma, Italy |
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5:00pm
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Photoactivated Adenylyl Cyclase
(PAC): A Novel Blue-light Receptor Flavoenzyme Mediating Euglena
Photomovement 1M. Iseki, 2S. Matsunaga, 3A. Murakami, 4K.Shiga, 5M. Sugai, 6T. Takahashi, 7D. Hader, 1,8M. Watanabe, 1National Institute for Basic Biology, Okazaki, Japan, 2University of Tsukuba, Tsukuba, Japan, 3Kobe University Research Center for Inland Seas, Iwaya, Japan, 4Kumamoto University School of Medicine, Kumamoto, Japan, 5Toyam University, Toyam, Japan, 6Toho University, Funabashi, Japan, 7Friedrich-Alexander University, Erlangen, Germany, 8Graduate University for Advanced Studies, Hayama, Japan |
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| 5:30pm-6:00pm | President's Member Reception | |
| 6:00pm-6:40pm Salle de Bal |
Business Meeting | |
