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Ciprofloxacin (Cipro), a fluoroquinolone antibiotic that can cause photosensitivity and phototoxicity reactions. Patients taking Cipro should avoid excessive exposure to sunlight.The current issue of Photochemistry and Photobiology is a Symposium-in-Print devoted to "Pharmaceutical Photochemistry". The editor is Guilherme L. Indig (University of Wisconsin, Milwaukee), long-time ASP member who has previously published four articles in Photochemistry and Photobiology.
One of the major articles in this issue is a review by Virginie Lhiaubet-Vallet and colleagues, entitled "Photosensitized DNA Damage: the Case of Fluoroquinolones". Fluoroquinolone (FQ) antibiotics, such as Ciprofloxacin, Levofloxacin, and Moxifloxacin, are well-known photosensitizers of DNA damage. This article reviews the in vivo evidence for photocarcinogenesis mediated by FQs, the methods used to detect FQ-mediated DNA photodamage, and additional topics.
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